Raj Rajnarayanan Profile picture
May 1 18 tweets 16 min read Twitter logo Read on Twitter
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

49.7% XBB.1.5
8.3% XBB.1.16
8.3% XBB.1.9.1
2.3% XBB.1.9.2
2.1% XBB.1.16.1
1.6% XBB.1.5.1
1.4% XBB.2.3

>> Low Sequence Count <<
#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/30/23

1/n
#COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.1%)
XBB.1.9.1 (8.0%)
XBB.1.16 (3.5%)
FL.2 (1.7%)
XBB.1.5.1 (1.7%)
XBB.1.5.17 (1.7%)
XBB.1.9.2 (1.4%)
XBB.1.5.15 (1.2%)

2/n Image
Airport sequences constitute a significant proportion of sequences (~27%; #15DayTrends)

Its going to be a three way race to outcompete XBB.1.5*: XBB.1.9* vs XBB.1.16* vs XBB.2.3*

As of now, XBB.1.16* family looks to over take everything else!

3/n Image
Sequence count by US States

#NewYork and #California have submitted a big share of sequences with specimen collection dates on or after 04/15/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

4/n Image
.@CDCgov updated variant proportions estimates on 04/28/2023 (updated every Friday)

Prudent to start tracking EG.1*, XBB.1.16.1 & XBB.2.3* as well



5/n
XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

6/n
XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/03/3…

7/n
Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already!
public.tableau.com/app/profile/ra…

8/n
.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults


9/n
#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19

public.tableau.com/app/profile/ra…

10/n
#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group):public.tableau.com/app/profile/ra…

11/n
Status of the latest #COVID19 Wave in #NewYork #Bellwether #State

XBB.1.5 is still the top circulating lineages in NY

[includes airport surveillance seqs]

12/n ImageImage
Status of the latest #COVID19 Wave in #California

XBB.1.5 is still the top circulating lineage in CA (#15DayTrends)

[includes airport surveillance sequences]

13/n ImageImage
USA Airport surveillance update #15DayTrends

155 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

14/n Image
As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?

"Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD
webmd.com/covid/news/202…

15/n Image
The next pandemic could be ‘as infectious as this one but far more lethal’—and make COVID look like a cakewalk, expert warns

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/04/2…

16/n
Observational data recorded by the LACDPH suggests those who have been infected with the rapidly spreading Omicron strain XBB.1.16 — better known as Arcturus — have shown symptoms of conjunctivitis.

nypost.com/2023/04/30/new…
"Given limited data, it is too early to know with certainty if XBB.1.16 is truly associated with higher rates of conjunctivitis, amid an already active allergy season in Southern California"

ph.lacounty.gov/phcommon/publi…

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More from @RajlabN

May 2
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

56.2% XBB.1.5
6.1% XBB.1.9.1
4.5% XBB.1.16
2.2% XBB.1.5.1
2.1% XBB.1.9.2
1.4% XBB.1.5.13
1.4% XBB.1.5.15
1.4% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 05/01/23

1/n Image
#COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.7%)
XBB.1.9.1 (5.5%)
XBB.1.16 (2.4%)
XBB.1.5.1 (2.3%)
XBB.1.5.13 (1.6%)
XBB.1.5.17 (1.6%)
XBB.1.9.2 (1.6%)
XBB.1.5.15 (1.3%)
FD.2 (1%)

2/n Image
Airport sequences constitute ~12.4% of sequences with sample collection dates in the last 15 days (#15DayTrends)

Its going to be a three way race to outcompete XBB.1.5*: XBB.1.9* vs XBB.1.16* vs XBB.2.3*

As of now, XBB.1.16* family looks to over take everything else!

3/n Image
Read 17 tweets
May 1
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 8,182 (circulating in 43 countries)

Tracker:public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated:05/01/23 Image
Tracker now includes all the designated XBB.1.16* sub-lineages

Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally Image
Read 4 tweets
Apr 30
Tracking #SARSCoV2 #Lineages - Globally

Top lineages -#20DayTrends (#G20):

XBB.1.5 (36.6%)⬇️
XBB.1.9.1 (11.5%)⬆️
EG.1 (4.7%)⬆️
XBB.1.16 (4.4%)⬆️
XBB.1.9.2 (3.1%)
XBB.2.3 (1.8%)
XBB.1.5.13 (1.6%)
XBB.1.16.1 (1.5%)

public.tableau.com/app/profile/ra…

Updated 04/29/23 Image
Granular details #Global #20DayTrends

This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 04/09/2023 (14,137 sequences) Image
#USA, #Austria, #France & #Canada have submitted a lion's share of sequences with sample collection dates on or after 04/09/2023 ...followed by #UnitedKingdom, #Australia, #Germany, #Sweden, #SouthKorea, #Singapore, #China, #Spain Image
Read 8 tweets
Apr 21
#SARSCoV2 #VariantProportions - #USA |04/21/23

New @CDCgov #Nowcast estimates:

Top circulating lineages:

XBB.1.5 (73.6%)⬇️
XBB.1.16 (9.6%) ⬆️
XBB.1.9.1 (7.9%)
XBB.1.9.2 (2.9%)
XBB.1.5.1 (2.2%)
FD.2 (1.6%)
XBB (1%)

covid.cdc.gov/covid-data-tra…

1/n Image
Over all trends are consistent with #15DayTrends (based on sequences uploaded in the public databases)

XBB.1.5 is still at the top; followed by XBB.1.16 & XBB.1.9.1

Expect XBB.2.3 to feature in the @CDCgov dashboard soon!



2/n
XBB.1.16* hotspots per CDC #Nowcast

>5% spread in almost all regions

Region 6 estimate reads 14.4% (looks more reasonable than the previous week's estimate of 21.3% spread which looked suspect; )

3/n Image
Read 4 tweets
Apr 21
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

52.8% XBB.1.5
9.5% XBB.1.16👀
4.7% XBB.1.9.1
2.6% XBB.1.16.1👀
2.3% XBB.1.9.2
1.3% EG.1
1.2% XBB.2.3
1.2% XBB.1.5.15

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/20/23

1/n Image
Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (64%),
XBB.1.9.1 (3.8%),
XBB.1.16 (3%),
XBB.1.5.19 (1.6%),
XBB.1.9.2 (1.4%)

2/n Image
Sequence count by US States

#NewYork & #California have submitted a big share of sequences with specimen collection dates on or after 04/05/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

3/n Image
Read 17 tweets
Apr 20
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 4,837 (circulating in 37 countries)

Tracker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance
Updated:04/20/23 Image
New entrant: #Bulgaria Image
Tracking #SARSCoV2 lineage XBB.1.16.1 over time - Globally

Total Sequences : 1003

racker: public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated: 04/20/23 Image
Read 4 tweets

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