Thread by @RajlabN

#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

56.2% XBB.1.5
6.1% XBB.1.9.1
4.5% XBB.1.16
2.2% XBB.1.5.1
2.1% XBB.1.9.2
1.4% XBB.1.5.13
1.4% XBB.1.5.15
1.4% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 05/01/23

1/n

#COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.7%)
XBB.1.9.1 (5.5%)
XBB.1.16 (2.4%)
XBB.1.5.1 (2.3%)
XBB.1.5.13 (1.6%)
XBB.1.5.17 (1.6%)
XBB.1.9.2 (1.6%)
XBB.1.5.15 (1.3%)
FD.2 (1%)

2/n

Airport sequences constitute ~12.4% of sequences with sample collection dates in the last 15 days (#15DayTrends)

Its going to be a three way race to outcompete XBB.1.5*: XBB.1.9* vs XBB.1.16* vs XBB.2.3*

As of now, XBB.1.16* family looks to over take everything else!

3/n

Sequence count by US States

#California, #NewYork and #Arizona have submitted a big share of sequences with specimen collection dates on or after 04/16/2023

XBB.1.5 is still at the top spot; followed by XBB.1.9.1 and XBB.1.16

4/n

.@CDCgov updated variant proportions estimates on 04/28/2023 (updated every Friday)

Prudent to start tracking EG.1*, XBB.1.16.1 & XBB.2.3* as well

https://twitter.com/RajlabN/status/1651967457064628228

5/n

XBB.1.16 has the potential to outcompete all other circulating lineages.

Everyone is closely watching XBB.1.16 hotspots for clues

Tracker: public.tableau.com/app/profile/ra…

6/n

#SARSCoV2 lineage XBB.1.16* (#Arcturus) is spreading in #UnitedStates

https://twitter.com/RajlabN/status/1653150354538901504

7/n

XBB.1.16 is one of the fittest variant in circulation right now.. and is picking up additional mutations... "its the one to watch"

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/03/3…

8/n

Predicted Immune Escape and ACE2 binding of top lineages in USA (relative to BA.2)

Bivalent boosters (OG/Omicron.BA.5) will potentially protect the boosted from getting severe disease/ hospitalizations.

Get updated if you haven't already!
public.tableau.com/app/profile/ra…

9/n

.@CDCgov has authorized a second dose of the bivalent Omicron-BA.5 vaccine for older adults and immunocompromised adults

https://twitter.com/RajlabN/status/1648819491378192384

10/n

#Hospital #Capacity - (by State/Division)

All hospitalizations not just COVID-19
public.tableau.com/app/profile/ra…

11/n

#COVID19 #Hospitalizations in the #UnitedStates

>60 yr old & immunocompromised Have a good look at @CDCgov info on #Boosters!

#Ventilate Indoor spaces

Sick? --> Wear a good quality #Mask!

Hospital Tracker (by States, by age group):public.tableau.com/app/profile/ra…

12/n

Status of the latest #COVID19 Wave in #NewYork #Bellwether #State

XBB.1.5 is still the top circulating lineages in NY

[includes airport surveillance seqs]

13/n

Status of the latest #COVID19 Wave in #California

XBB.1.5 is still the top circulating lineage in CA (#15DayTrends)

includes airport surveillance sequences

14/n

USA Airport surveillance update #15DayTrends

118 sequences from 6 US States (#California, #NewYork, #Washington, #NewJersey, #Georgia and #Virginia) from @CDCgov's Traveler-Based Genomic Surveillance Program.

*Includes pooled swabs & Many bad QC seqs

15/n

As COVID Tracking Wanes, Are We Letting Our Guard Down Too Soon?

"Closing up shop too early could mean we are blindsided" “You have to maintain a base level of sequencing for new variants"

H/T @DohenyKathleen @WebMD
webmd.com/covid/news/202…

16/n

The next pandemic could be ‘as infectious as this one but far more lethal’—and make COVID look like a cakewalk, expert warns

H/T @ErinMPrater @WellatFortune
@FortuneMagazine
fortune.com/well/2023/04/2…

17/n