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Evan Allen @EAllen0417
, 6 tweets, 3 min read Read on Twitter
Next up we have the Baltimore Longitudinal Study of Aging. This looked exclusively at 501 men free of disease at the outset that were followed for 18 years. Seven day diet records were recorded at multiple (up to 7x) intervals in the study.
The BLSA took so long that the nutrition calculations method were changed over the course of the study, but the investigators were scrupulous and unified the methods before the final analysis. The most interesting choice they made was dividing dichotomous variables into binaries.
So someone who ate 4 servings of fruit and vegetables daily was grouped with someone who had none, but someone who had 5 was grouped with someone who had 10. SFA was cut at 12% because almost nobody ate <10% SFA. jn.nutrition.org/content/135/3/…
The findings are remarkable. Just as with the well-done study from yesterday, SFA was strongly and significantly associated not just with CVD mortality, but also all-cause mortality. For CVD, the most important variable was SFA, for overall mortality, it was F&V intake.
People are eager not to die. Sometimes proponents of SFA consumption will suggest that they can't even prevent heart disease if the risk is already high. I would argue this study suggests the opposite. The high, FV, low SFA group did amazingly well. eatingacademy.com/cholesterol-2/…
Next up will be the last of the SFA and CVD papers from S-T and K, the Strong Heart Study of native Americans done by Xu.
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