Discover and read the best of Twitter Threads about #MicroRounds

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🤔 📖 📱

Is Twitter The New ID Textbook?

Bugs, Drugs, and Social Media – Twitter as a Tool for Advancing the Field of Infectious Diseases

My #ECCMID2022 slides as a 🧵 1/n
Many ingredients in the kitchen of social media can be combined to create different products which supports advancing ID through SM.

Each activity can support one or multiple domains of 🧠 Blooms Taxonomy.

Get creative with your recipes to create new fun stuff! 2/n
One of the best accounts out there on SM @DGlaucomflecken - huge reach in short period, recent ASP skit in vertical video, very entertaining & original, uses several SM platforms.

REMEMBERING domain: ⚠️ beware inappropriate meropenem prescribing.

3/n
Read 11 tweets
Many times when susceptibility testing is done for P. aeroginosa, a scenario similar to shown in the picture is encountered.
We see that TZP has produced a D shape on the IPM side. This might look very similar to the phenomenon seen in gram positive ICR strains. So what is it?
Published data says that this result is most likely due to
inducible expression of the P. aeruginosa AmpC beta-lactamase.
Certain enteric
(Serratia, Providencia, Citrobacter, Enterobacter, Morganella) and non-enteric organisms (P. aeruginosa, Aeromonas) can up-regulate expression of
their chromosomally-encoded ampC genes in response to sub-inhbitory concentrations of certain
b-lactam antibiotics
Read 10 tweets
#MicroRounds (Day 733): Hypothetical case: a parent hears their child use the toilet but not flush (typical behavior!).

But upon entering the bathroom they're horrified to see this worm in the bowl with their kid's poop! How freaked out should they be?? #ASMClinMicro #IDTwitter A split picture: a tangled skinny worm (thinner than a stran
Cont.: Here's some additional information (from your friendly neighborhood parasitology lab).
1) Yes, it's actually a worm.
2) You zoom in close and see this on one of the ends of the worm... A split, three pronged brown worm.
#MicroRounds: If you see this worm in your toilet: relax. It didn't come from a person!

A horsehair worm. Nematomorpha (i.e. "looks like a nematode") is a phylum that infects grasshoppers, crickets & drives them to water. A common false human parasite #ASMClinMicro #IDTwitter A tangled brown worm (skinnier than spaghetti). Caption read
Read 6 tweets
Thoughts on upcoming #COVID19 #serology tests:
This is actually quite a challenge! (#Diagnostics often involve a lot of complexities). There is a lot of pressure to roll these tests out, but they need to perform well, or we do more harm than good. #MicroRounds (A thread)
WHY we need these soon:
1. Contact tracing.
2. Can be used to test if a vaccine is working during a clinical trial (70 of them ongoing right now, I believe)
3. Inform public policy makers about rate of asymptomatic cases + previous infections/exposures =informed decision making
How is developing a #PCR different than developing a #serology test?
1. #PCR tests detect viral RNA/DNA (in this case RNA) and can be pretty straight-forward in terms of development
2. #Serology relies on knowing about the #SARSCoV2 structure and how the human body responds.
Read 13 tweets
1/ Yday on micro rounds we discussed Group A streptococcus (GAS). We briefly touched on the rationale behind using adjunctive clindamycin for severe forms of invasive GAS. So here is a short tweetorial on the topic. @CarlosdelRio7 @Dr_AmyKacin @colleenkraftmd
2/ GAS is an aerobic GPC. GAS invasive disease (iGAS) is defined by isolation of GAS from a normally sterile body site. The most severe of these invasive disease entities are generally thought to be necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS).
3/ Currently, the addition of clindamycin therapy to B-lactams and surgical debridement is recommended by the IDSA for Necrotizing fasciitis and used routinely in management of STSS, despite low rates of PCN resistance . What is the rationale?

doi.org/10.1093/cid/ci…
Read 11 tweets

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