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La competencia entre países del Golfo por alcanzar mayores cuotas de influencia a través de la diplomacia religiosa ha sido feroz en las últimas décadas.
Durante el #MundialQatar2022 profundizaré en el papel de #Qatar con especial atención a sus actividades en #España (Hilo...)
Durante el #MundialQatar2022 profundizaré en el papel de #Qatar con especial atención a sus actividades en #España (Hilo...)
La ONG #qatar|í @qcharity lanzó en 2015 un ambicioso programa de financiación con fines proselitistas denominado #Ghaith con el objetivo de «introducir la cultura islámica y fortalecer su presencia entre las comunidades occidentales».
gulf-times.com/story/450457/Q…
gulf-times.com/story/450457/Q…
El paso del tiempo es el mejor aliado de los teóricos de la conspiración pero hasta que llega ese momento se nos insulta, se nos difama y se nos silencia.
11-m
11-m
Masonería militar de la OTAN y La Gran Logia Nacional de Francia: El despliegue de los servicios secretos hispano-franco-marroquíes.
To the Zapatista Army of National Liberation
To the National Indigenous Congress
To the Indigenous Governing Council
To the Sexta National and International
To Slumil K'ajxemk'op
To national and international human rights organizations
To the National Indigenous Congress
To the Indigenous Governing Council
To the Sexta National and International
To Slumil K'ajxemk'op
To national and international human rights organizations
Today, April 2, on the twelfth day of the Caravan for Water and Life, in the community of Alcozacán, Chilapa, Guerrero, our colleagues from CIPOG-EZ, after finishing the day's activities, reported the presence of 50 vans and 20 motorcycles ...
... from the organised crime group "Los Ardillos" in the community of Colotepec, Chilapa, one of the points through which the caravan would travel to continue its journey.
Ces enfants ne brandissent pas le drapeau français mais celui du Koweït. Depuis Strasbourg, ils ne célèbrent pas le 14 juillet mais le 25 février: la fête nationale du Koweït. Des islamistes reçoivent le pétrodollar koweïtien. Ces enfants sont instrumentalisés pour dire: merci !
Ces enfants apprennent l'arabe, le Coran et l'islam, selon la lecture islamiste des Frères musulmans, à l'Institut Al-Andalous (Andalousie) que finance le #Koweït. Son recteur, le frère musulman Messaoud Boumaza, a rejoint le Conseil national des imams, voulu par @EmmanuelMacron.
Dans cette vidéo, publiée par la chaîne des Frères musulmans @MF_Musulmans (ex-UOIF), l'islamiste Messaoud Boumaza, raconte au frère musulman Anas Saghrouni son parcours militant et idéologique, depuis sa formation à l'#IESH à Château-Chinon en 1992:⤵️
#Fotosdelasemana Fotos del 14 al 19 de septiembre de 2020. Esta semana #ConfinamientoSelectivo, #DER20Madrid, entrevista con @DGobiernoMadrid @conJoseMFranco, @QuimTorraiPla en el #supremo, el colegio privado SEK Ciudalcampo en tiempo de pandemia y la directora del #CNI
1/
Another #immunosuppression #tweetorial...spotlight today on #belatacept today
How do you say it? @Babybel @MedTweetorials
Another #immunosuppression #tweetorial...spotlight today on #belatacept today
How do you say it? @Babybel @MedTweetorials
2/
Belatacept is the FUSION protein that has been the @NKOTB in #kidneytransplant - having been approved for use in 2011.
What's fused?
1. Human IgG1 Fc fragment
2. Extracellular domain of cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4)
pubmed.ncbi.nlm.nih.gov/25416857/
Belatacept is the FUSION protein that has been the @NKOTB in #kidneytransplant - having been approved for use in 2011.
What's fused?
1. Human IgG1 Fc fragment
2. Extracellular domain of cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4)
pubmed.ncbi.nlm.nih.gov/25416857/
3/
The goal of this fusion protein? Disrupt Signal 2⃣ of the 3⃣-Signal T-cell activation pathway
Signal 2 = Binding of CD28 (on T-cell) to B7-1/B7-2 (on APC)
This important step is called co-stimulation and is necessary for T-cell activation
nejm.org/doi/full/10.10…
The goal of this fusion protein? Disrupt Signal 2⃣ of the 3⃣-Signal T-cell activation pathway
Signal 2 = Binding of CD28 (on T-cell) to B7-1/B7-2 (on APC)
This important step is called co-stimulation and is necessary for T-cell activation
nejm.org/doi/full/10.10…
Richard Burt seems interesting.
#Diligence #Deripaska #Rothschild #Kissinger #Gazprom #Fridman #Alfa #CNI #Simes #Mayflower
en.wikipedia.org/wiki/Richard_B…
#Diligence #Deripaska #Rothschild #Kissinger #Gazprom #Fridman #Alfa #CNI #Simes #Mayflower
en.wikipedia.org/wiki/Richard_B…
HILO.⤵
"Atentados del 11 de marzo de 2004"
«El origen de los servicios secretos hispano-franco-marroquíes del 11-M.»
#SocialismoRadicalEspañol
#DinastíaAlauí
#PSOE
#GranOrienteEspañol
#GranLogiaNacionalDeFrancia
#OTAN
#CNI
@PeonesNegros
"Atentados del 11 de marzo de 2004"
«El origen de los servicios secretos hispano-franco-marroquíes del 11-M.»
#SocialismoRadicalEspañol
#DinastíaAlauí
#PSOE
#GranOrienteEspañol
#GranLogiaNacionalDeFrancia
#OTAN
#CNI
@PeonesNegros
@PeonesNegros Índice
I. Gran Oriente Español en Marruecos (1905)
II. Introducción de la monarquía marroquí en la francmasonería (1920-1927)
III. Fundación de la Gran Logia de Marruecos por masones españoles residentes en el norte de África (1923)
I. Gran Oriente Español en Marruecos (1905)
II. Introducción de la monarquía marroquí en la francmasonería (1920-1927)
III. Fundación de la Gran Logia de Marruecos por masones españoles residentes en el norte de África (1923)
@PeonesNegros IV. Masones y militares españoles en el Norte de África (1923-1936)
V. Gran Oriente Español: Distrito de Marruecos durante la II República Española (1931-1936)
VI. Logias del Gran Oriente Español durente la Guerra Civil Española (1936-1939)
V. Gran Oriente Español: Distrito de Marruecos durante la II República Española (1931-1936)
VI. Logias del Gran Oriente Español durente la Guerra Civil Española (1936-1939)
1/ Continuing the #immunosuppression #tweetorial series...@MedTweetorials
Today's player: #mTORi, mammalian/mechanistic target of rapamcyin inhibitors
Rapamcyin was @US_FDA approved for #kidneytransplant in 2003.
It was isolated from a soil sample from which island in 1975?
Today's player: #mTORi, mammalian/mechanistic target of rapamcyin inhibitors
Rapamcyin was @US_FDA approved for #kidneytransplant in 2003.
It was isolated from a soil sample from which island in 1975?
2/ Meet mTOR, a phosphatidylinositol 3-kinase (PI3)-related kinase (adds a phos). mTOR adds a phosphoryl group to serine/threonine residues.
It is a key component of the complexes mTORC1 and mTORC 2 - which regulate processes including cell growth, proliferation, and survival.
It is a key component of the complexes mTORC1 and mTORC 2 - which regulate processes including cell growth, proliferation, and survival.
3/ mTOR inhibition blocks "Signal 3" of #TCell activation - reducing cytokine dependent cell proliferation and activation.
Take a look at all 3 signals below 👇🏽
nejm.org/doi/full/10.10…
Take a look at all 3 signals below 👇🏽
nejm.org/doi/full/10.10…
Ministry of Truth
@JosepBorrellF asks #Spain's Superior Court of Justice to close #Catalan delegations in London, Geneva & Berlin for "damaging Spain's image" based on documents intercepted by his toytown spy network and social media posts.
#BorrellGate
1
catalannews.com/politics/item/…
@JosepBorrellF asks #Spain's Superior Court of Justice to close #Catalan delegations in London, Geneva & Berlin for "damaging Spain's image" based on documents intercepted by his toytown spy network and social media posts.
#BorrellGate
1
catalannews.com/politics/item/…
London
The delegation is accused of ''retweeting messages in favour of Gibraltar" and criticising Borrell's comment on us history: "they only had to kill a handful of Indians".
In this case, surely it was Borrell was "harming #Spain's image"?
#BorrellGate
2
The delegation is accused of ''retweeting messages in favour of Gibraltar" and criticising Borrell's comment on us history: "they only had to kill a handful of Indians".
In this case, surely it was Borrell was "harming #Spain's image"?
#BorrellGate
2
London
Borrell's toytown diplomats found it "damaging to #Spain's image" that "there were barely 20 people" at an event with Parliament VP, @josepcosta: an Estelada on a table "looked like a coffin" and "people mocked it on social media"
#BorrellGate
3
ccma.cat/324/lespionatg…
Borrell's toytown diplomats found it "damaging to #Spain's image" that "there were barely 20 people" at an event with Parliament VP, @josepcosta: an Estelada on a table "looked like a coffin" and "people mocked it on social media"
#BorrellGate
3
ccma.cat/324/lespionatg…
No-show of #Spanish police and intelligence officials - Trapote, Gonzalo, Pérez de los Cobos - before commission investigating terror attacks #Catalonia, Aug '17. Disrespect of #Catalan institutions and still no news of what they knew.
#ThisIsTheRealSpain
elmon.cat/politica/el-cn…
#ThisIsTheRealSpain
elmon.cat/politica/el-cn…
Absentees:
Ex-chief of CNP Cat, Sebastián Trapote
Dir. CNI, Félix Sanz Roldán
Ex-chief of Civil Guard Cat, Ángel Gonzalo
Interior Ministry rep. to Security Commission Cat, Diego Pérez de los Cobos
Dir. of CITCO, José Luis Olivera Serrano
Ex-DG of CNP, Germán López Iglesias
2
Ex-chief of CNP Cat, Sebastián Trapote
Dir. CNI, Félix Sanz Roldán
Ex-chief of Civil Guard Cat, Ángel Gonzalo
Interior Ministry rep. to Security Commission Cat, Diego Pérez de los Cobos
Dir. of CITCO, José Luis Olivera Serrano
Ex-DG of CNP, Germán López Iglesias
2
#Spain’s secret service (#CNI) admitted “contacts” with Abdelbaki Es Satty, the mastermind behind the terror cell but didn't clarify their frequency, duration or remuneration, only that they were within the “protocol established for convicts” 17/11/2017
3
elpais.com/elpais/2017/11…
3
elpais.com/elpais/2017/11…
1/
A brief #tweetorial on the calcineurin inhibitors #CNI and their toxicities. Let's start with a quick poll.
Which of the following describes the main mechanism of action of #CNI?
A brief #tweetorial on the calcineurin inhibitors #CNI and their toxicities. Let's start with a quick poll.
Which of the following describes the main mechanism of action of #CNI?
2/
On to the mechanism of #CNI. Calcineurin inhibitors bind to the "immunophiliins" for which they are named. Cyclosporine (CsA) binds cyclophilin and tacrolimius(FK506) binds FK binding protein.
The CNI-immunophilin complex is the superhero which then inhibits calcineurin
On to the mechanism of #CNI. Calcineurin inhibitors bind to the "immunophiliins" for which they are named. Cyclosporine (CsA) binds cyclophilin and tacrolimius(FK506) binds FK binding protein.
The CNI-immunophilin complex is the superhero which then inhibits calcineurin
3/
Meet calcineurin, whose superpower is a calcium-dependent PHOSPHATASE: enzyme that uses H2O to cleave phosphoric acid into a phosphate ion and an alcohol (read: removes phos)
Normally, calcineurin dephosphorylates NFAT - allowing it to freely swim into the nucleus.
Meet calcineurin, whose superpower is a calcium-dependent PHOSPHATASE: enzyme that uses H2O to cleave phosphoric acid into a phosphate ion and an alcohol (read: removes phos)
Normally, calcineurin dephosphorylates NFAT - allowing it to freely swim into the nucleus.
This thread contains images with passages from the Mueller Report. I will add new ones as I create them.
If you want, share them on Facebook, Instagram, print on fliers or t-shirts or postcards.
I want to show America what's in that report.
If you want, share them on Facebook, Instagram, print on fliers or t-shirts or postcards.
I want to show America what's in that report.
If you can, don't try managing your own @kubernetesio clusters. It can become a huge engineering effort in itself very quickly. If the core business product is not around providing infrastructure to others, using #kubernetes solutions provided by cloud providers is not a bad idea
There are exceptions of course, but most of the times you wouldn't require switching out components in the control plane, or installing custom #CNI plugins out of the plethora, these would be taken off your plate and then you can focus on solving other things in your plate.
If someone on a small team brings #Kubernetes expertise to the table, it is worth considering. Otherwise, if you're at the stage where your team is focusing on building the product, then #k8s is probably going to end up being a distraction.
Anyone who gives Senator My Dad Is Putin's Bitch and I'm Named After Ayn Rand airtime deserves a deep dive.
cc: @thespybrief @gametheorytoday
h/t @fire_resign
cc: @thespybrief @gametheorytoday
h/t @fire_resign
boop.
Simes.
of course.
Simes.
of course.
Yuri Ushakov and Dimitri K. Simes sitting in a spy dacha.
C-O-L-L-U-D-I-N-G
C-O-L-L-U-D-I-N-G
