OAI5 attack again at bottom, kill two humans. 4-1. ~1k gold advantage. ~10k gold advantage is generally considered impossible to recover from in professional play.
OAI5 trash talk: Above 99%.
Entire human team is wiped out, OAI5 have lost a single hero. OAI5 having taken Tier 3 tower and barracks now backing off to regroup.
Human reaction time: "The average (median) reaction time is 215 milliseconds, according to the data collected so far"
I would argue the issue is not reaction time but ability to evaluate global information in detail.