Optionality- It is far better to have a massive supply of Actemra/RoActemra (tocilizumab) and not need it, than to need it and not have it. clinicaltrialsarena.com/news/roche-act…
"Optionality is the property of asymmetric upside (preferably unlimited) with correspondingly limited downside (preferably tiny).”
"If you have optionality your assessment doesn’t need to be made beforehand, only after the outcome." NNT
This optionality has massive value.
"If you have optionality your assessment doesn’t need to be made beforehand, only after the outcome." NNT
This optionality has massive value.
"An option [creates more] upside than downside...select among the results what fits and forget about the rest Payoffs from research are from Extremistan; they follow a power statistical distribution, with big, near-unlimited upside but, because of optionality, limited downside.”
