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Madeline Sterling, MD

@mad_sters

, 5 tweets, 19 min read

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@boback

@boback

@boback @JDNewmanMD @CircOutcomes @iamritu @bnallamo @MikeTPhD @ADAlthousePhD @denniskomd @SVRaoMD @rallamee @rajkumar_chris @GreggWStone @KAlexanderMD @jspertus 22/ We are also seeing disparities by race, gender, age, and location... Women were likely to reach goals @drstaceyrosen @ErinMichos - why? Also non-whites more likely than white participants to achieve LDL-C goal at 1 year, converse to other studies.

@boback

@boback

@boback @JDNewmanMD @CircOutcomes @iamritu @bnallamo @MikeTPhD @ADAlthousePhD @denniskomd @SVRaoMD @rallamee @rajkumar_chris @GreggWStone @KAlexanderMD @jspertus @drstaceyrosen @ErinMichos 23/ Older adults had higher odds of attaining LDL goal, but lower odds SBP goal. North America had greater odds of reaching LDL and SBP goals compared to other regions.

@boback

@boback

@boback @JDNewmanMD @CircOutcomes @iamritu @bnallamo @MikeTPhD @ADAlthousePhD @denniskomd @SVRaoMD @rallamee @rajkumar_chris @GreggWStone @KAlexanderMD @jspertus @drstaceyrosen @ErinMichos 24/ Finally no association b/n medication adherence & treatment target. Adherence to lipid lowering or antihypertensive medication did not increase the likelihood of meeting LDL target (OR 0.97, 95% CI 0.83-1.14) or SBP target (OR 1.00, 95% CI 0.84-1.20) @venkmurthy @iamritu

@boback

@boback

@boback @JDNewmanMD @CircOutcomes @iamritu @bnallamo @MikeTPhD @ADAlthousePhD @denniskomd @SVRaoMD @rallamee @rajkumar_chris @GreggWStone @KAlexanderMD @jspertus @drstaceyrosen @ErinMichos @venkmurthy 25/ Must read accompanying editorial “The Goldilocks Guide to getting Medical Therapy “just right”: Insights from the ISCHEMIA trial” @rajkumar_chris
@rallamee @MikeFoley89 offer additional interpretation and guidance for Saturday, #AHA19 ahajournals.org/doi/10.1161/CI…

@boback

@boback

@boback @JDNewmanMD @CircOutcomes @iamritu @bnallamo @MikeTPhD @ADAlthousePhD @denniskomd @SVRaoMD @rallamee @rajkumar_chris @GreggWStone @KAlexanderMD @jspertus @drstaceyrosen @ErinMichos @venkmurthy @MikeFoley89 26/ Data show modest cardiovascular risk target attainment (52% of pts achieved LDL target & 75% reached SBP target at 1 yr). Efforts to do this though, seem like anything but 'modest' -- size and scope of trial tremendous. Achieving targets for OMT is v. hard in trial and IRL!

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