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After reviewing 'predictive modelling & radiomics' abstracts for #ESTRO202, I had quite a few thoughts. I've finally found time to organise them in a semi-coherent manner

To follow: Some common pitfalls in modelling & radiomics abstracts for clinical conferences #radonc #medphys
First of all, the basic stuff:
Get somebody who’s never seen your study before to read through the abstract - to ensure fundamental information isn't missing.
(And no, you won't notice yourself, because you’re too concerned with whether you can squeeze in another AUC value ...)
If you are submitting to a radiotherapy conference, maybe make clear what the relevance is for radiotherapy? Several image analysis / radiomics / AI abstracts were probably technically excellent, but I scored them low due to lack of radiotherapy relevance
For ESTRO, you are allowed figures. Use them! Really! Why would you write a whole abstract about dose-response relationships, radiomic features, image processing, etc, without illustrating even a small part of this?
For the nitty-gritty stuff:
If you report a prognostic model, make sure to actually define your outcome measure. Yes, some of you didn't ...

And if you are reporting on a late endpoint - survival, tumour control, late tox, etc - I want to know your follow-up (time)
State your statistical methods. Some of you forgot to note which regression model you used ... for a prognostic modelling abstract, I kind of need to know this!

Also: That you 'corrected for clinical factors' just make me wonder if you even know what clinical factors are
“We extracted imaging biomarkers / radiomic features / etc” is not a sufficient methods description for a radiomics abstract. Especially if you don’t tell us which volume you extracted features from. By now, I expect radiomics studies to conform to IBSI
Further on standardization and guidelines:
It takes >35 characters to state that you followed the TRIPOD guidelines.

(You all followed the TRIPOD guidelines, right? Right?? All the previous deficiencies notwithstanding??)

tripod-statement.org
Some of you also need reminding that
'univariate' -> 'multivariate'
still isn't a robust way to select your predictors.

And neither is forward / backward / stepwise variable selection.

Please.

towardsdatascience.com/stopping-stepw…
sciencedirect.com/science/articl…
However, to end on a positive note:
1) Some excellent model performance reporting this year (not just AUC, yay!)
2) And multiple studies with external validation cohorts (more yay!)
So all in all, we're getting better, as a field 😀
And I'm now definitely looking forward to seeing you all - and your posters and presentations - in Vienna in April! Image
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