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A number of media reports this week on potential treatments for #COVIDー19. @WHO is tracking these developments and will update our treatment guidelines if any evidence emerges. Right now, what is needed are high quality #RCTs@JeremyFarrar @ICMRDELHI @Chikwe_I @jarottingen @MRCza
The @WHO #Solidarity trial will test chloroquine or HCQ, lopinavir/ritonavir with and without interferon beta, remdesivir versus Standard of care in many countries round the world, in order to generate robust evidence on mortality and hospitalization of #COVIDー19 patients
The #Solidarity protocol is an adaptive clinical trial - so more arms can be added later, arms can be dropped for futility. A global data safety monitoring committee and steering committee (of international experts) will oversee the trial @WHO.
We are grateful to the companies who have agreed to donate drugs for this trial - Gilead, Merck, Cipla, Mylan and AbbVie - it has been a pleasure working with them. With global #solidarity, we can overcome this new threat to humanity
As of now, there are no specific anti #COVIDー19 compounds that have proven efficacy. Many in vitro studies, patient case series, small RCTs; but none that clearly establishes efficacy & safety of any of the proposed drugs. High quality research is the need of the hour @DrTedros
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