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While not often emphasized the first instance of economic globalization came into being after 1241 Mongol raid on Eastern Europe that devastated Russian principalities, Hungary, Serbia-Bosnia & Bulgaria but subsequently allowed & encouraged...

Genghis Khan
trade between China, Middle East & Europe. Marco Polo's remarkable journey was made possible by the Pax Mongolica that was reaching through tributaries from Baltic & Adriatic Sea to Sea of Japan & Indian Ocean.
Among the 1st Westerners to venture across the Mongol empire were the Franciscans tasked by the Pope to find "Prester John's country". They collected a wealth of info about Central Asia & China. most famous among them, Flemish William of Rubruck, got to W China in 1250s.
Genoese tradesmen supported them logistically but also availed of the trade opportunities & set up a great network of colonies connecting E & W.
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