Discover and read the best of Twitter Threads about #colitis

Most recents (7)

In our project, we want to find a definitive cure for #IBD 🏥 using an innovative strategy🧬🔬 We explain this in our latest infographic and in this tweetorial. Get on board! 👇🏻 Image
We are researching #IBD because it affects millions of people worldwide, especially young adults 👦🏻👧🏻 Moreover, we target two of the most frequent IBD subtypes: #Crohns disease and ulcerative #colitis 👇🏻
We focus on the main issue of #IBD: inflammation 🔥 In this condition, the patient’s immune system attacks their #intestine as if it were an external agent. Image
Read 9 tweets
My first piece on #multiomics #IBD as part of my thesis is out as a preprint!

I'll summarize it on this thread…
First, we check how the many parameters of RGCCA #rstats influence and work in their original dataset. We check that different designs select different variables, we discard the superblock design.

2/x ImageImageImage
Then we look our own dataset of #IBD samples undergoing a treatment and some controls. We use a method to find good models of the data. The method is available as #rstats package, with its own #pkgdown website
3/x Image
Read 9 tweets
Virophages are small #viruses w/ double-stranded DNA genomes that replicate along with giant viruses + co-infect eukaryotic cells 👉@DaviPaez @kyrpides + team just published this study which increased the number of known virophage genomes by 10-fold!:… ImageImage
2/ It’s the first study to identify HQ virophage genomes in diverse habitats including #plant-associated, thermal #springs, deep-subsurface and #cow rumen...
3/’s also the first study ever to identify virophages in human #gut samples! 👉 4/5 human-associated HQ virophage genomes were identified in #fecal samples recovered from individuals with a rural lifestyle, the other was found in a patient w/ ulcerative #colitis Image
Read 3 tweets
The UCP does NOT understand how devastating removing brand name biologics from the list of covered drugs could be. Let me…
Biological drugs are very expensive. They are genetically engineered antibodies that target specific molecules in our bodies that contribute to a disease process (like cancer, inflammation). They do not always just block the molecule from engaging it’s receptor.
Sometimes they have other actions (like inducing apoptosis/cell death) or activating receptors, or signaling other cells to eat the molecule/cell that the antibody binds to. That means that depending on how the antibody was originally designed, the therapeutic effect is different
Read 10 tweets

Remarkable @bmj_latest @BMJCaseReports report documenting the extreme lengths a bedbound patient went through to get a diagnosis of #POTS, #MCAS, #SIBO and #tachycardia

read her story here

#MedEd #MedTwitter @MayoClinic…
2. After suffering for 16 years, seeing 19 docs with repeated misdiagnosis:

Her cardiologist couldnt diagnose #POTS

Her gastroenterologist couldnt diagnose #SIBO

Her immunologist couldnt diagnose #MCAS

Her neurologist referred her to a #psychiatrist!…
3. Patient: the "neurologist was out of ideas and suggested I get a psych evaluation, which I declined"

the patient <referred herself> to @MayoClinic

#SickNotWeak #chronicillness #chronicpain #MedEd #medtwitter…
Read 10 tweets
7 September 2018  #BeatCancer
@Bradleysfight May Bradley Rest In Peace and his family and friends always be comforted by his memory. I hope the #HelenRollasonAward 2017 from BBC
Sport will have helped them.
7 September 2018  #BeatCancer
@harry_moseley @Jack_Marshall_ May they
Rest In Peace and may their families and friends always be comforted by their memory.
7 September 2018  #BeatCancer
@Rachael_Hodges @steveevans51 @_StephensStory May Rachael
Bland, Steve Evans and Stephen Sutton Rest In Peace and their family and friends always be comforted.
Read 18 tweets
Dr L in the buzzfeed article says humans make alpha-gal sugar, But, here’s a podcast & transcript w/Dr Commins, Prof at UNC Allergy & Immunology who was part of the discovery team in 2009 & is an expert on AG. He says humans don’t make alpha-gal sugar./1…
Dr Commins also clarified that the 2009 discovery involved the lone star tick but that it can be caused by other ticks. His research is ongoing. I disagree w/him on 2 things:
1) I Do think anyone w/a tick bite should be tested for the allergy apprx 6 weeks after the bite.
2) The reaction does not always cause itching. I’ve found the random palm itching to be more common than torso hives, but, even more common than that is no hives. And, I agree that the allergy response, unlike other food allergies, is delayed. Dr C say apprx 4 hrs after/3
Read 9 tweets

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