Discover and read the best of Twitter Threads about #leonardieffect
Most recents (15)
Seems like many are still unaware or downplaying the immune imbalance triggered by SARS infections š² We all have friends constantly battling respiratory issues, but remember, the plural of anecdote is not data.
So here is a mega thread of sick posts
So here is a mega thread of sick posts
Substantial evidence is mounting to corroborate the phenomenon commonly referred to as the #LeonardiEffect
~ SARS Epidemic ~
Situation update for China for week of: March 23
#ZeroCOVID #Azvudine #PASC #SAND #LongCOVID #LeonardiEffect #AirborneAIDS #Incurable
š§µ
chinacdc.cn/jkzt/crb/zl/szā¦
Situation update for China for week of: March 23
#ZeroCOVID #Azvudine #PASC #SAND #LongCOVID #LeonardiEffect #AirborneAIDS #Incurable
š§µ
chinacdc.cn/jkzt/crb/zl/szā¦
1 (1) - New cases have levelled off to 3,575/week
1 (2) China conducted a total of 40,000 tests the week of March 23, down from their peak of 1.9 million back in mid-December.
Use of the proper tests to analyze how immune t-cells (CD4+, CD8+) respond to SARS-CoV infection or vaccination, it's fairly clear SARS-CoV infection damages the CD8+ t-cells regardless of prior immunity.
Hybrid immunity is a false narrative.
Immunity debt is a false narrative
Hybrid immunity is a false narrative.
Immunity debt is a false narrative
Vaccination of patients induces robust CD4+ & CD8+ t-cell responses to the virusā spike protein. In addition, these t-cells produced multiple types of cell-signaling molecules (cytokines), which recruit other immune cellsāincluding antibody-producing B cellsāto fight pathogens.
However, patients who had been infected with SARS prior to vaccination produced spike-specific CD8+ T cells at considerably lower levelsāand with less functionalityāthan vaccinated people who had never been infected.
sciencedirect.com/science/articlā¦
sciencedirect.com/science/articlā¦
1. The art and craft of policy or the āthere is no carā problem, as roy scranton calls it
2. Even if we had a driver, thereās a bigger problem: no car.
No problem for our friends over at @Wankpanzer!
No problem for our friends over at @Wankpanzer!
3. If you canāt handle the road ahead, no biggie: just follow the flow š
1. Mechanics of SARS-acquired immune harm denial
FascinatingāI hope epidemiological sociologists are collecting all the data, so we may learn from it. This entire article describes the #LeonardiEffect - @fitterhappierAJ - without ever connecting the dots.
taz.de/Kranksein-in-pā¦
FascinatingāI hope epidemiological sociologists are collecting all the data, so we may learn from it. This entire article describes the #LeonardiEffect - @fitterhappierAJ - without ever connecting the dots.
taz.de/Kranksein-in-pā¦
@fitterhappierAJ 2. Who will tell audience and artists?
What needs to happen, i.e. what level of population-wide organ or immunological damage do we need per unit time, for people to realize that this isn't sustainable AND that states could stop it any time if they cared?
taz.de/Kranksein-in-pā¦
What needs to happen, i.e. what level of population-wide organ or immunological damage do we need per unit time, for people to realize that this isn't sustainable AND that states could stop it any time if they cared?
taz.de/Kranksein-in-pā¦
3. Poor bedside manners is to ask "how many idiots need to die before people focus". Sometimes poor beside manners are exactly what we need to help normal people understand what IS ahead if they don't change direction. This thread for problem and solution.
Viral persistence depletes lymphocytes & once depleted the patient's immune system starts destroying healthy tissue -> starting with the brain.
#SAND==#HAND
Damage to immunity is #incurable
Damage to the brain is #incurable
Damage can be prevented IFF persistence was tested
#SAND==#HAND
Damage to immunity is #incurable
Damage to the brain is #incurable
Damage can be prevented IFF persistence was tested
RNA viral infections can give rise to a systemic decline in the number of lymphocytes in the blood, referred to as acquired lymphopenia. Lymphopenia may affect the patient's adaptive immune responses and impact the clinical course of chronic symptoms.
merckmanuals.com/professional/hā¦
merckmanuals.com/professional/hā¦
We have detailed scientific and medical knowledge on how viruses such as HIV & Ebola induce lymphopenia and have valuable information into the pathogenesis of viral infections and potential therapeutics targeting lymph node recovery that we aren't using for SARS-CoV
1. mpox: human monkeypox virus (hMPXV) doesn't enter the nucleus. Genetic recombination with SARS-CoV-2 in the cytoplasm is possible in co-infected patients, eg people living with uncontrolled HIV-1 (PLH). It's the real threat of Covid Denial or Let 'er RIP policy.
#SIDU 230206
#SIDU 230206
2. Covid can have the same effect, causing lymphopenia in perhaps 1 in 3 patients (severe #LongCOVID (#LongSARS) can be compared to HIV/AIDS).
Influenza, SARS, HIV, mpox Protein E8L follow shared evolutionary dynamics for electrostatic surface potential & co-receptor switching.
Influenza, SARS, HIV, mpox Protein E8L follow shared evolutionary dynamics for electrostatic surface potential & co-receptor switching.
3. Practical implication for clinicians: Test patients presenting with mpox symptoms for all three diseases.
Practical implications for all else: read science.
sciencedirect.com/science/articlā¦
mdpi.com/1999-4915/15/2ā¦
mdpi.com/1420-3049/27/1ā¦
mdpi.com/1999-4915/14/1ā¦
Practical implications for all else: read science.
sciencedirect.com/science/articlā¦
mdpi.com/1999-4915/15/2ā¦
mdpi.com/1420-3049/27/1ā¦
mdpi.com/1999-4915/14/1ā¦
1. You want freedom from COVID-19?
(1) Three community measures ended SARS 2003, H5N1 2009:
N95+eye protection,
test & trace,
isolation of the infected;
(2) Two at the international level:
travel surveillance & quarantine (never used 2020).
Itās a political science problem. š
(1) Three community measures ended SARS 2003, H5N1 2009:
N95+eye protection,
test & trace,
isolation of the infected;
(2) Two at the international level:
travel surveillance & quarantine (never used 2020).
Itās a political science problem. š
2. It doesn't matter if you 'believe in' human immune system (HIS) damage from SARS-CoV-2. It just IS.
Here a poetic Reality Check Marker thread. Read all; my shortcut for HIS question.
Political scientists and lawyers will need to learn to read science.
Here a poetic Reality Check Marker thread. Read all; my shortcut for HIS question.
Political scientists and lawyers will need to learn to read science.
3. It doesn't matter if you 'believe in' constitutional or human rights law. It just IS.
I translate because even highly educated people with a strong STEM or humanities background don't easily make the connection.
The hallmark of a true systems problem.
I translate because even highly educated people with a strong STEM or humanities background don't easily make the connection.
The hallmark of a true systems problem.
#DontLookUP and this syndemic of RSV/influenza/SARS is every indicator that society of Corporate Democracies can stare 5 million people dying and walk around the dead.
People are not motivated by equality because they donāt want to join the dying. We all have natural instincts for survival and we know that staying out of poverty is a means of not dying.
We could be at the threshold of the zombie apocalypse where a brain eating virus that requires 5 years to manifest encephalitis. But banks are still collecting mortgages so the zombies are still working and paying taxes!
1. Happy 2023 everyone! š„³š¤
2. Why donāt we have the manufacturing capacity and Health Care Workers to get everyone the care the deserve?
3. The family of Long COVID is growing at a rate of 100,000+ patients per day!
States are defying their legal obligations by not collecting data and not reporting to WHO as they should under IHR 2005.
States are defying their legal obligations by not collecting data and not reporting to WHO as they should under IHR 2005.
(1) How will states stop SARS?
We covered the problem; let's explain the solution next year to help people
These elements sustain the pandemic:
(a) Airborne transmission
(b) Immunodeficiency
(c) Lack of leadership
Walensky speaks the truth. CDC can't control (c). #SIDU 221231
We covered the problem; let's explain the solution next year to help people
These elements sustain the pandemic:
(a) Airborne transmission
(b) Immunodeficiency
(c) Lack of leadership
Walensky speaks the truth. CDC can't control (c). #SIDU 221231
(a) airborne spread is known and we have solutions: Check ā
(b) immunodeficiency/#LeonardiEffect are deniable. Read @RealCheckMarker @fitterhappierAJ
It's dynamic: no solutions but (a) will work. Check ā
(c) Unaccountable leadership is the problem. āļø
(b) immunodeficiency/#LeonardiEffect are deniable. Read @RealCheckMarker @fitterhappierAJ
It's dynamic: no solutions but (a) will work. Check ā
(c) Unaccountable leadership is the problem. āļø
@RealCheckMarker @fitterhappierAJ (3) Now reframe the question
How can states stop (a) airborne spread and (b) individual and population-level immunodeficiency to end the pandemic with the tools available (WHO IHR 2005)?
What is the alternative (BATNA) if they don't?
Here the solution:
How can states stop (a) airborne spread and (b) individual and population-level immunodeficiency to end the pandemic with the tools available (WHO IHR 2005)?
What is the alternative (BATNA) if they don't?
Here the solution:
Brutal. Important update. Thanks you three:
Complete mystery to me how this was ever even a question.
I think this is important to emphasize. Children - infantsā lives! - are at stake here. Harsh, criminal justice questions are in order for authorities who purposely and systematically, for years, infected an entire generation. We have no idea how these children will grow up.
Kids with RSV were more likely to have had Covid!
Evidence of the #leonardiEffect at work, @DavidJoffe64!!
Thanks @ariccio
People like Rasmussen said it wouldnāt exist!!
Evidence of the #leonardiEffect at work, @DavidJoffe64!!
Thanks @ariccio
People like Rasmussen said it wouldnāt exist!!
Earlier I presented the elaboration of the hypothesis to include the hit to plasmacytoid dendritic cells and their interferon alpha production following mild covid, which would reduce resistance to infection with rsv
It looks like I was right! Hits to the immune system from covid are opening the door to outbreaks from and susceptibility to other viruses! This is me taking a bow! š
@NjbBari3 @farid__jalali All three of you are partially correct. I find it fascinating everyone here is batting around theories of autoimmune disorder when political forces have opened up a population level experiment but nobody is collecting data.
@NjbBari3 @farid__jalali Prior to this SARS outbreak the most common infection that lead to lymphopenia was HIV. Now we are seeing varying degrees of autoimmune disease but nobody is applying the simple AIDS tests of t-cell depletion!
@NjbBari3 @farid__jalali The trigger for cytokine response and cause of lymphopenia are more likely a result of prion creation of persistent viral infection which damages all systems including immunity.
Dr. @fitterhappierAJās warning is going viral. Congrats. States start to admit COVID harms the immune system, making OTHER viruses severe to children, adults & the aged. #LeonardiEffect
He was silenced for warning.
So so many will die for the insane policy of ālet āer R.I.Pā š¢
He was silenced for warning.
So so many will die for the insane policy of ālet āer R.I.Pā š¢
German health minister @Karl_Lauterbach here admits the #LeonardiEffect. Most others donāt. @rki_de
States could implement existing, binding law to end (!) the pandemic any day (WHO IHR 2005), but refuse to. Thus COVID is fast becoming humanityās worst public health disaster. š¤¦š»āāļø
States could implement existing, binding law to end (!) the pandemic any day (WHO IHR 2005), but refuse to. Thus COVID is fast becoming humanityās worst public health disaster. š¤¦š»āāļø
āNo one could have knownā
No, we knew and have been warning you all for more than two years. You knew
Policymakers and journalists chose to ignore us and ridiculed us as zero SARS āzealotsā
You support ZeroAIDS, but not ZeroCOVID
This makes no sense.
No, we knew and have been warning you all for more than two years. You knew
Policymakers and journalists chose to ignore us and ridiculed us as zero SARS āzealotsā
You support ZeroAIDS, but not ZeroCOVID
This makes no sense.
