(28-23) advantage over the Virginia Tech hokies who only started trying to compete in football in the 1980s. I couldn't believe what I found.
27 wins over Washington and Lee(D2)
21 wins against the Richmond Spiders(D1AA)
Here's the kicker, this doesn't even include their 200+ wins against teams recently moved to the Big East void such as S Florida, Cinci, and Temple.