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First completed systematic review on antimalarials (#hydrochloroquine #chloroquine) for #Covid_19
It is a rigorous SR conducted rapidly, NOT a rapid review (less rigour)
Submitted today to journal but preliminary report here to avoid delay in decision-making (1/4🧵)
For others to replicate, we share search strategy and downloadable files
Published and ongoing studies continuously updated here:
app.iloveevidence.com/loves/5e6fdb96…
Let's advocate for #replication not #duplication (waste) in evidence synthesis.
Also, collaboration more than welcome (2/4🧵)
It includes first RCT with reported data.
It has negative findings. Portrays different picture than questionable study hitting the news days ago (Gautret et al)
Thanks to @ConfucioUST for translation (Chinese to English). We are exploring copyright issues before sharing
(3/4🧵)
We identified almost 30 ongoing studies, so the evidence will be changing at a fast pace. We will maintain a web-based living systematic review (to be released after publication in the journal) and resubmit if changes are substantive
#livingsystematicreview #L·OVE
(4/4🧵)
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