1/ #Sleep & #Dementia: @NatureComms
 
Study of ~8,000 people followed for 25 years! Look at the figures. Sleeping <7 hrs per night chronically increases risk of dementia by 30%.  Get your sleep!

go.nature.com/3tjRxJB

#MedTwitter #MedEd #Geriatrics
2/ Sleep and Dementia Risk: @nytimes

@PamBelluck wrote a great article on this NatureComm paper showing heightened risk of #dementia for “short-sleepers,” defined as <7 hrs of sleep a night.

nyti.ms/3h7KZeV

#Aging #Delirium
3/ What’s the Mechanism?

Our brain’s “trash” clearance (like the body’s Lymphatic system but by brain’s “glial” cells & called Glymphatics) kicks into ⬆️ gear in sleep. So less sleep is like your waste management system going on strike. Kapische??

REF: bit.ly/3eQxtte
4/fin
As a physician & scientist, I lived ~25 years on 4-5 hrs of sleep/night. Just because I could doesn’t mean I should. We didn’t know all this then. Now I get >=7 hrs/night & feel a LOT better. Maybe, just maybe, I won’t get #dementia early & be ⬇️ of a burden to my wife!
People like @sleepdiplomat & @davideagleman are revolutionizing our knowledge in areas of #sleep & #neuroplasticity. Maybe Dr. Walker or Dr. Eagleman can chime in on this 🧵??

#ScienceTwitter #MedTwitter #AcademicTwitter #NurseTwitter

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More from @WesElyMD

3 May
1/ 🧵A picture is worth 1,000 words 👁 #COVID19:

This 🎥 shows a clear example of what can happen to a person’s body w #COVID. His wife asked me to show it on twitter & urges everyone to get #vaccinate

(w/ consent of pt & wife)

#MedTwitter #NurseTwitter #CriticalCare
2/ You’ll notice his eyes are swollen shut. (Written perm to show). This is not fluid. It’s AIR from inside his chest leaking out his lungs 🫁 through muscles & skin to his neck & into his face. He is AWAKE & communicating but had ICU #delirium earlier.

#MedStudentTwitter #Nurse
3/ Look at his chest CT. See the “L” lungs w #Covid pneumonia/#ARDS & also AIR leaking out under his skin. Now go back to 1st tweet & watch 🎥 again. This is called “barotrauma” & happens when the 🫁s get too stiff and pop. Difficult situation. We’re hoping he can heal!

#MedEd
Read 5 tweets
29 Apr
1/ End of Life in #COVID19...
yesterday I was removing life support from a patient, according to his wishes as stated by his wife, to convert the goals of care to comfort measures only. I took some time in the room alone with him & considered...
@pallipulm #palliativecare
2/ just for a moment all the very difficult & also excellent things that happened in my own life that no one else understood. Then I looked at my patient & realized he had just as many highs & lows that only he knew. Here was an infinite treasure of a person...
#MedTwitter #Nurse
3/ and the actions I was about to take would allow his life to come to a peaceful natural end. I committed to do everything I could for him to make sure he didn’t suffer as he sauntered out of life. What a privilege & honor to be allowed to enter into the miracle of him...
Read 7 tweets
28 Apr
Extra-Bad Blood🩸Vessel Dz in #COVID19:

1. Immunogenic HITT (heparin-ind thrombocytopenia & thrombosis) NOT from heparin but #Covid itself. Bilateral arterial clots.

2. TSS (toxic shock synd) + #COVID - nightmarish clotting in legs/arms = like burns

#MedTwitter #Nurse #Vaxx
1/ Since others asked, our diagnosis of “spontaneous immunogenic HITT” was made by positive HIT ELISA (an immunoassay) showing the presence of anti-PF4 IgG antibodies even though he had not been (past or present) on heparin. This in setting of #COVID19.
2/ He also had an abnormal functional assay of platelet-activating capacity of PF4/heparin-Ab complexes, though there are slight differences in results of his assay vs. typical HIT. He now has 2 problems (#COVID & HIT) causing potentially life-threatening arterial thrombosis.
Read 4 tweets
19 Apr
1/ #Mentorship 🧵

This woman is my #mentor (pic w perm). Joan W Bennett. She’s in @theNASciences as geneticist & mycologist. Today we are at the Parthenon in Nashville TN where after 35 YEARS, she still provides me council…

bit.ly/3mWqDWN

#MedTwitter #Sciencetwitter
2/ Dr. Bennett taught me that mentorship is not a job w an endpoint. She assumed this role IN my life FOR life. Today we talked as much about parenting as science. We are in each other’s front row. This is the depth of a true mentor-mentee relationship.
 
#MedEd @theNAMedicine
3/ Like any relationship, there must be chemistry & connection. If you don’t have that w a “mentor,” maybe you have the wrong person. Build a relationship not a business arrangement. It’s also NOT just a trajectory to promotion. #Mentorship is “whole” person care & development.
Read 11 tweets
14 Mar
1/ Do data support pt trial off sedation for “SAT” when pt is comfortable on current dose? Yes
 
Shared w permission:
“Dr. Ely, yesterday our ICU #nurses went over #A2Fbundle in Epic for implementation. Do you recommend SAT at RASS Goal of RASS -1 to +1?
#medtwitter #criticalcare
2/ Excellent #Nurse added:

“We are currently not doing SAT (Spontaneous Awakening Trial) but keeping pt’s RASS -1 to +1.  Just want to make sure we are interpreting #A2Fbundle correctly.”
 
#TipsForNewDocs
#medstudenttwitter #COVID19 #pandemic
3/ my Answers:

Great questions. I don’t think +1 (anxiety) is ever a good goal but 0 to -1 is a 👍 default target RASS if we acknowledge there are times when sedation target should acceptably be set as deep as -3/-4 in bad #ARDS or -5 transiently when pt requires paralytics.
Read 8 tweets
11 Mar
1/ Home w my 84 y/o Mom for 1st time since 2019 because of #COVID19…She raised 3 of us alone on $17k/yr as a lit teacher after dad left. A few things she’s said that are hilarious... Image
2/ Today we saw an classmate from my grade school & Mom didn’t remember her.

Me: “Mom, she’s really smart, wise, kind, & gentle of heart.”

Mom: “So I guess that’s why you didn’t hang out with her much.”

😳 Zing!
3/ Mom thinking 🤔 ...“Wes, remember when I got us a tent to take you kids camping? I had you set it up in the backyard to make sure we knew how. Then I thought, ‘Hmm, this is good...why don’t you 3 just live out here from now on!’”
Read 6 tweets

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