Discover and read the best of Twitter Threads about #ScienceTwitter

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50 yo female with progressive eye redness and loss of visual acuity. She has a h/o hypertension. Thoughts? #MedEd
#MedTwitter #health #healthcare #FOAMed #ClinicalPearl #clinicaltips #neuroscience #neurotwitter
#sciencetwitter #brain #medstudenttwitter #medical Image
Neuro intact other than vision.
What is reason for redness, specifically?
Read 4 tweets
How wounds heal

#woundhealing #injury #homeostasis #angiogenesis #epidermal #skin #MedTwitter #meded #foamed #InnoMed

Timelapse Of A Wound Healing
#epidermal #medtwitter #meded #foamed #InnoMed #homeostasis #injuy #woundhealing #sciencetwitter

How does #aging affect #WoundHealing?
#scRNAseq identifies major changes in cell compositions, kinetics, and molecular profiles during #woundhealing in aged #skin @CellReports
bit.ly/3PZMies
#epidermal #MedTwitter #meded #foamed #InnoMed #bioinformatics #homeostasis
Read 4 tweets
Under Newton, we were free to explore the cosmos: 1686-1905.

Einstein then enforced house arrest to our solar system:1905-Now.

@elonmusk then said chemical rockets could get us 2 more spheres w Newtonian laws.

But survival hinges on going *beyond* Einstein, not back to Newton.
I’m not going to complicate the basic story with caveats. That’s the basic plot.

Either there is freedom to leave based on new ideas, like GU, or the Einsteinian restrictions will persist.

If they persist; we probably can mildly elongate survival here by decades via wisdom.
But if we can leave to explore the universe by going beyond Einstein, anyone else out there can visit.

This brings us to UFO/UAP. Assuming a distribution of life in the cosmos:: some life is behind us in science, with others ahead.

A (loose) argument then links UAP to survival:
Read 6 tweets
Do you feel confused over how to write a #LiteratureReview, clueless about why we write this or where to start? A lot of us started there!

Here's my idea to
Write a #LitRev in 5 definitive steps🧵

#LiteratureReview #AcWri #PhDtips #AcademicTwitter #ScienceTwitter #PhDlife
1️⃣ Start by identifying the 𝗴𝗼𝗮𝗹. These questions will guide your literature collection and writing of the review:
— Why this problem?
— What has been done before and where's the research gap?
— What other methods exist, and why could the chosen method fill the gap? 1. Identify the goal of the review Why am I solving this par
2️⃣𝗖𝗼𝗹𝗹𝗲𝗰𝘁 relevant literature to answer the above questions by starting from a root paper, branch out and then narrowing down to your theme.
I'd suggest @rsrchrabbit for this step. (I've already made a reel about this and you can find it in my recent story/highlights.) 2. Collect relevant articles to answer the above 4 questions
Read 9 tweets
Undergrads & new grad students - NOW is the time to start thinking about applying for the @nsf GRFP!
A thread of advice I've accumulated on how to write a successful application...🧵
#AcademicChatter #phdchat #NSFfunded #STEM #scicomm #sciencetwitter #NSFGRFP
1/20
I applied to the NSF GRFP twice, & was successful the 2nd time; I chalk up that success to my advisors at RGGS, Carthage, & Marquette, & so most of the advice below comes from them.
2/20
First, what is the GRFP? Put simply, it's a competitive fellowship funded by the @NSF that replaces or supplements your graduate stipend & provides some funding to your institution. It is open to US citizens who are, or will be, grad students (MS & PhD) in #STEM fields.
3/20
Read 20 tweets
It's a season of lab rotations for PhD students!! Students - Go to every lab with a broad, open outlook, interact & learn. Think about which topic drives the passion in you, see which lab environment you would fit best into! #AcademicTwitter #AcademicChatter
There are many factors to carefully ponder upon before you choose & make your decision. Think it through as grad school forms the basis & foundation of your career in science be it academia, industry, other allied careers!
#science #sciencetwitter
You spend a significant amount of time of the peak of your career in grad school in the lab hence choosing the right lab & the research that you are most passionate and driven about becomes highly important!
@VoicesofIndAcad @PhDVoice
Read 7 tweets
Important point I need to address. Ur prob right, @neurosutras. 😊

I def don’t want/intend to be a jerk.

I took a calculated risk with my boldness. It’s *mostly* for the trainees.

Mini 🧵

#AAIC #AAIC2022 #AAIC22 #sciencetwitter #AcademicTwitter #AcademicChatter #phdchat
1. Bad talks are a serious problem for all attendees, but esp. for trainees. Trainees often leave conferences feeling “stupid” because they didn’t understand most talks. Why wouldn’t they? The speakers are “experts”. Turns out trainees aren’t the problem. The talks were bad.
2. Trainees see “experts” give talks and copy their techniques. Bad habits perpetuate.
Read 7 tweets
I’m still surprised by the poor talks at scientific conferences, including from 99% of PIs (regardless of institution). Yes, it likely includes you. Sorry.

My goal is NOT to criticize, but to help.

🧵

#AAIC #AAIC2022 #AcademicChatter #AcademicTwitter #phdchat #ScienceTwitter
If you’ve ever been to a talk you didn’t understand, it’s probably because the talk was poorly done. It’s not because you’re “stupid”.

We need better presentation training. Conferences would be much more impactful.

Conferences should include regular trainings.
I’m not the greatest presenter, but I have learned some great techniques that really help your audience.

Some of these tips are adapted from things I learned in Writing in the Sciences by @KristinSainani.

Everyone should take her course (including/esp. senior PIs)
Read 30 tweets
Time for another #sciencetwitter journal club! Today's paper: #Microdosing with #psilocybin #mushrooms: a double-blind placebo-controlled study by Cavanna et al 2022! Hot off the presses!

nature.com/articles/s4139…
This study has:

34 participants, about half of which had previous experience with psychedelics

Randomized, double-blind placebo-controlled, within-subjects design

0.5. g psilocybin mushroom in capsule and edible, non-psychedelic mushroom as placebo
typical "microdose" is 0.1 - 0.5 g of dried mushrooms, which still can produce some type of altered consciousness, hallucination effect depending on the person.

most common regimen is 1 day on 2 days off, based on Fadiman's work.
Read 17 tweets
Right. It's not just Trump — the whole rightwing enterprise, from the billionaire donors, to the thinktanks, to the staffers is making plans to destroy the government.

And that's important: Gov't destruction and autocratic control will happen under ANY Republican president.
It's not just Trump.
Ron DeSantis will do exactly the same, backed by all these conservative organizations. /2
And this has enormous consequences for universities and scientists.

This rightwing effort to destroy and corrupt government will lead directly to science funding being corrupted. /3
Read 11 tweets
Hey #ScienceTwitter,

I'm using inclusive language when teaching the reproductive systems, eg: pregnant person.

I tripped up today talking about fetal circulation. What's a better term than maternal circulation? Parental implies either parent. I want something more specific
Oh, this blew up in the wrong way. So let's clarify for the haters.

Women are people.

Not all women can get pregnant

Some girls can get pregnant and are not women.

Some trans men can get pregnant and are not women.

Inclusive language is more precise and respectful.
Read 3 tweets
Some long weekend reflection as we work to build effective research infrastructure around #LongCovid and other infection-associated chronic illnesses like #MECFS and #Lyme. For those who don't know, I was born and raised in Perth, Western Australia, so here's a "local" story. 1/
Apologies if this is a familiar story to many, but I think there is much wisdom to be gained. For the longest time, gastric ulcers were thought to be related to excess acid in the stomach and worsened by stress/lifestyle. People were treated for peptic ulcers with antacids and 2/
the recommendation to reduce stress in their lives. This went on for decades until a Perth-based physician/scientist, Dr Barry Marshall, made an accidental discovery that led him to believe that gastric ulcers may not be stress-related at all: in fact they might be a result of 3/
Read 13 tweets
Ok #AcademicTwitter. This month, I'm entering my 3rd year of PhD! yayy🎉

I was looking through my 1st research journal and found these "tips" I had written for myself. I thought I'll share them here.

So, here's a 🧵of #PhDtips for those starting their PhD!

#PhDlife #PhDchat Image
1. Maintain a #PhDjournal📒
Experiments, results, failures, meetings w/ guide, seminars, weekly plans, proposal brainstorming, talk prep - everything related to your PhD in one notebook.

(coursework & journal notes can be separate, but I used the same note. 1 note/year for me)
2. Read a lot of journal articles. A lot.
It is the best way to take your research forward!

(I wanted to try the #365papersChallenge, but couldn't keep up. I read way fewer papers than I want myself to. This could be my sign from the universe to step up!)
#journalclub
Read 9 tweets
Have you ever searched for "How to do a #LiteratureReview quickly/in 1 day/3 hours"?
And then spend the entire time getting lost in searching/ wallowing in tangential directions?

Here is a🧵on Quick #LitRev technique...

#AcWri #AcademicTwitter #PhDtips #phdlife #ScienceTwitter Image
From my fair share of struggle with literature reviews, I devised a technique that helped me do *quick* literature surveys, especially when I needed to
- write a #grant #proposal
- improve a half-written #manuscript
- learn a new method/theory

So, here you go...
1️⃣Collecting literature: Research Rabbit App

My go-to tool for literature discovery+visualize connection b/w them. (very essential for writing your LitRev, as you will need to draw connections between different works.) Image
Read 14 tweets
13 months since I reported an obvious case of plagiarism. The paper is still online. Journal gone silent and no longer replying to emails.

Ready to name and shame both authors and the journal.

@OpenAcademics @AcademicChatter #academictwitter #sciencetwitter
@OpenAcademics @AcademicChatter First author on the paper that plagarised ours: orcid.org/0000-0002-0805… as you can see he has a v large number of papers across multiple research topics.
@OpenAcademics @AcademicChatter I picked a paper of his at random, copy and pasted the first few lines of the abstract and oh look, its copied from another article as well.
Read 32 tweets
New episode out today! Join us for a conversation with @LesinskiLab where we chat about his professional journey and his career as a translational researcher. Listen in and hear some #sciencebehindthescenes. #behindthemicroscope apple.co/34z7OUS
@LesinskiLab @WinshipAtEmory @EmoryMedicine @EmoryUniversity @A_P_S_A @sitcancer @CancerBioEmory @laneygradschool @LaneyEDGE @emoryhealthcare Dr. Lesinski (@LesinskiLab) completed his undergraduate studies at @bgsu before continuing on to Medical College of Ohio (now @UToledoMed) to complete his PhD in biomedical sciences.
He then continued on to @OhioState to complete a postdoctoral fellowship and an MPH in clinical investigation, eventually joining the faculty at @OhioStateMed.
Read 11 tweets
As always, context matters! This only applies to Australian Humpback whales. Other populations are still listed as #endangered by the USA & all are in @CITES Appendix I. The @IUCNRedList assessed Humpback whales as a Least Concern species for #conservation abc.net.au/news/2022-02-2…
I also find this interesting because I often see people who study #conservation & #WildlifeTrade argue that CITES and US Endangered Species Act listings should all mirror the IUCN Red List assessments. But I doubt the same people would agree when it means removing protections...
Necessary Reminder: Each of these 3 systems are independent processes because each serves a unique purpose. They can overlap & feed into one another, but to assume they should always agree is to misunderstand the policies & processes they represent #WildlifeTrade #ScienceTwitter
Read 5 tweets
Today I gave my first peer-review rejection. For a lot of reasons, it didn't feel good. It's exhausting to prevent science misinformation from spreading, especially when a paper can be resubmitted elsewhere & slip by different peer-reviewers #AcademicChatter #ScienceTwitter
And just to add context, I've rejected a lot of papers during peer-review before, but with the option of resubmission if minor or major revisions were made. But this time, it couldn't be fixed.
Is it weird I feel bad? I empathize with how much time & effort the authors must have invested, which made it hard for me to not to keep giving more chances to re-submit, especially after I volunteered so much of my own time into the review process as well. But this is science.
Read 4 tweets
Many times when susceptibility testing is done for P. aeroginosa, a scenario similar to shown in the picture is encountered.
We see that TZP has produced a D shape on the IPM side. This might look very similar to the phenomenon seen in gram positive ICR strains. So what is it?
Published data says that this result is most likely due to
inducible expression of the P. aeruginosa AmpC beta-lactamase.
Certain enteric
(Serratia, Providencia, Citrobacter, Enterobacter, Morganella) and non-enteric organisms (P. aeruginosa, Aeromonas) can up-regulate expression of
their chromosomally-encoded ampC genes in response to sub-inhbitory concentrations of certain
b-lactam antibiotics
Read 10 tweets
Episode 1 of the @HCTriage special series on the relationship between science culture and reproducibility: What IS the reproducibility crisis? healthcaretriage.info/reproducibilit…
In episode 1, we talk to @jamesheathers about his metascience work and related perspectives. We dig into his work on the Brian Wansink case, and we speak to @stephaniemlee about her extensive work breaking the stories on this major example of scientific misconduct.
We talk to @MicrobiomDigest about her incredible work in science integrity and image forensics, and what happens when she tries to report her findings to journals. Tidbit: 2/3 of the issues she's identified in papers have not been corrected over the course of FIVE years
Read 9 tweets
BIG PODCAST NEWS!!!

Thanks to funding from @NIH, a group of incredible experts, & the @HCTriage crew @crashcoursestan @olsenvideo @DrTiff_PhD, I’m excited to announce that the first 3 episodes of our podcast on science culture & reproducibility are live! healthcaretriage.info/reproducibilit…
@NIH @HCTriage @crashcoursestan @olsenvideo @DrTiff_PhD In this 8-episode series, we dig into questions about academic incentives, publishing and funding practices, training and mentorship, how the media plays into the problem, and finally, what we can do to fix things.
@NIH @HCTriage @crashcoursestan @olsenvideo @DrTiff_PhD The remaining episodes will release once per week for the next five weeks, and we will tag our experts as we roll this out! We want this to be a resource and conversation starter for the science community. Come listen!! #academictwitter#academicchatter #sciencetwitter #science
Read 4 tweets
Are There Hidden Genes in DNA/RNA Vaccines? (2022)🔔🆕

frontiersin.org/articles/10.33…

🧬Some ORFs on SARS-CoV-2 DNA/RNA vaccines, could lead to the translation of undesired proteins during vaccination

🧬Pfizer and Moderna vaccines were analyzed

#sciencetwitter
(1/3) Image
(2/3)

Translation of overlapping ORFs within larger ORFs can result in harmful effects on host tissues, such as interfering with organelle membrane protein activity or perturbing signaling pathways

The protein-coding potential of DNA/RNA vaccines should be investigated further Image
(3/3)

Notably, the Moderna mRNA-1273 vaccine sequence is predicted to contain no frameshifted ORFs on the positive sense strand, which highlights the utility of codon optimization in DNA/RNA vaccine design to remove undesired overlapping ORFs 👍
Read 3 tweets
On behalf of @USCViterbi Dean's Office, I'm organizing a free (virtual) 2-day workshop + "grad program fair" for UGs interested in pursuing grad degrees in STEM this summer. W/ 2days, we can cover many topics. What should we discuss? Who should I invite as speakers/panelists?
🧵
I did this previously and discussed the below in a series of panels (w/ lots of time for Q&A). I was thinking a similar format this time, along with a pair of a "plenaries" (but short talks w/ Q&A).

(Also, the below are on my group's YouTube channel.)
2/N
Also, I want to have a "grad fair" - like a career fair, but a place where grad schools from across the country can have "rooms" to answer Q's about their programs, applications, ..

@USC did a virtual career fair in the fall that worked, so I'm building on that framework. 3/N
Read 4 tweets
1/

New research shows that only 10% #Omicron cases are in ppl who have gotten #COVID19 #Booster.

This may be MISINTERPRETED as:

"Only 10% of people w/ #BoosterDose get #OmicronVariant"

OR

#BoosterShots are 90% effective"

Not that simple! READ ON!

medrxiv.org/content/10.110…
2/

First, this is NOT a critique of the study (currently a pre-print).

Researchers at @MethodistHosp who did this provided a VERY valuable piece of info and are not making any inappropriate claims. Great work!

It's just that it's easy for public/media to misinterpret results!
3/

Paper reports on a total of 1313 #OmicronVariant cases in the Houston, TX area.

See table below:
~49% of cases in those not vaccinated (0 or 1 does)
~51% are #BREAKTHROUGHS.

Of those #Breakthrough cases,

535 cases w/ 2 #vaccine doses
140 cases w/ 3 doses (i.e., booster) Image
Read 18 tweets

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