Discover and read the best of Twitter Threads about #ScienceTwitter

Most recents (24)

Sometime before 1565, an enormous deposit of graphite was discovered in Cumbria, England. The locals had been using the black powder to mark their sheep.
It was discovered that this #powder could be used as a refractory #materials to line molds for cannonballs, resulting in...1
...rounder smoother balls that fired farther because of better aerodynamics. This was so valuable to the English Navy that the mine came under the strict control of Queen Elizabeth I. The poor locals and miners began to smuggle chunks of graphite out of the mine. The French...2
...among others, paid a good amount. So the locals carried this material in their pockets, making their hands and clothes black and dirty. Thus, the dark black graphite opened up a secret and illegal #market. Over time, this came to be called the 'Black Market' #ScienceTwitter
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✨IT'S ASTROTIME✨
Stellar Nurseries
👶

That is the name for regions of space filled with gas and dust and bright young stars!

Active star formation is truly a thing of beauty 😍 just look at this. What can we you in this picture?

Look closer....

📸: prawn nebula/@ESO
Apart from the (gorgeous) blue stars, there are 2 main features:

1) Very bright areas:
That's where stars have just been born! 🤩 The most massive ones are so bright that they can heat the gas up to 10,000 degrees, making it glow! 😱

2) Dark areas: they look mysterious...
But they're really not 😉

These dark regions are dense "molecular clouds", that are roughly 1000 times colder than the bright areas!

They eventually fall in on themselves under their own weight, or get squished by the powerful winds of new stars. When they get dense enough...
Read 8 tweets
Lithium is the only metal to have been produced at the Big Bang. All other elements - except Hydrogen and Helium - were produced by stars - some in hot nuclear cores, others in fantastic explosions like a supernova.
The percentage of lithium in the Universe, however, is more ...
..or less the same today as it was at the beginning of time.
In other words, the lithium that powers your laptop is as old as the Universe itself! With only three protons and three electrons, lithium is a fragile element that is easily destroyed in the hot interior of stars...
The only exception to this rule is a class of Red Giant stars that are much heavier than the sun. These stars contain 1000 times more lithium than others. This result comes from a study of 200,000 stars observed with a host of large telescopes on earth and in space. These ...
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Working to become anti-racist requires that we research & acknowledge the persistence & gravity of structural racism, so we've created a series of 10 infographics about why racism is a public health problem. Here's the overview:
The full series with functional hyperlinks is on our website, & we'll be posting snippets throughout the coming days!
scipolucla.com/2020/07/30/rac…
Here are some myths we'll be disproving around race & public health!

#SciPol #scicomm #ScienceTwitter
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My day in the lab as a disabled person, a thread (feel free to RT).
I have cerebral palsy, autism (which I normally don't publicly admit), ADD and a learning disability. I'm also profoundly visually impaired. Those involved in #wormgate though it was ok to compare that joke to mocking the disabled.
This is just a form of tokenism from people who have NEVER in all their professional career, lifted so much as a finger to help this community.

Because some professors think it's ok to double down, I thought I'd do the sensible thing, and take you through my day in the lab.
Read 47 tweets
Just a thought: When we discuss #COVID19 severity varying in response to the dose of viral exposure, that likely also has a temporal component. 1/?
As in, clearing a virus from the body requires a coordinated response from multiple arms of the immune system, each of which takes different amounts of time to ramp up. Early innate response is quick, but largely incapable of responding to exponential growth. 2/?
So being exposed to a large dose of virus at once could lead to a hyperreactive innate response that causes exaggerated adaptive immune responses down the line. 3/?
Read 6 tweets
Dear Scientists: Is your research just?

Knowledge is power, and scientific research shapes and changes the world just as much as it describes the world. This thread is meant to help scientists reflect more critically on our own research and to mobilize science for justice. A graphic representation of this tweet with the title "
To review, Western science, which is built upon the exploitation and oppression of Black people and communities, is one part of institutionalized racism.
But we can build a more just science. B/c #ScienceIsPolitical, scientists must reflect on the values embedded in their research, and choose the systems that their research works to uphold or dismantle. How does your science perpetuate white supremacy? How does it combat racism?
Read 46 tweets
Got a lot of interest in my '30 days of @MATLAB tips I wish I had known in graduate school'. So I finished writing all 30+I'm posting them here. I hope these help people imagine and be creative, earn a living, and enjoy coding. Please share #ScienceTwitter #AcademicTwitter /30
I'm also conflicted about posting coding tips today. Much STEM research goes to support surveillance, militarization, and racist state violence. So please consider what you are doing today and what it means for someone else's tomorrow. Educate yourself. s/o @HellaBlackPod /30
First post on using "fun" operations in MATLAB (1/30)

medium.com/analytics-vidh…
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How do we quantify how much #virus is in a sample (titre). We use a plaque assay, which is why he most commonly used method. Below is a graphical version I've made (on @BioRender) of how it is done in the lab.

But how do they work? - a thread
#SciComm #Virology #phdchat
1/n
Here is a photo of a #SARSCoV2 assay, the virus which causes #COVID19 ( Photo: Müller/Charité). The large areas which are clear are known as plaques which are caused by virus killing cells in a monolayer. More plaques = more virus titre

#virology #sciencetwitter

2/n SARS-COV2 plaque assay
The technique was originally developed for #Bacteriophages bit was adapted by Dulbecco in 1952 for animal #viruses. Viral stocks are dilutes 10 fold in series and placed onto a monolayer. After incubation a gel is placed on the layer, restricting infection to nearby cells

3/n Plaques produced by Western equine encephalitis virus on chick embryo fibroblasts and by poliovirus on HeLa cells (right).  R. Dulbecco, 1952
Read 6 tweets
What’s the difference between colon and lung? Not an easy question when it comes to #KRAS. Our work out today in @CD_AACR today describe a strategy to overcome resistance to KRAS G12C inhibition in CRC. @sloan_kettering @Albert0Bardelli @BardelliLab bit.ly/2ACWd7H👇👇👇
Molecular response to KRAS G12C inhibitors is different in CRC and NSCLC models. CRC models show quick MAPK pathway rebound
Receptor tyrosine kinases and EGFR dependency is stronger in CRC models
Read 5 tweets
This Plandemic video with Mitkovic makes me feel rage, bewilderment, and fear all at once. It's slick, and it's dangerous. I personally think it's important to engage laypeople about this without snark and disdain. Here's my experience #ScienceTwitter #AcademicChatter
A family member sent it to me 2 days ago and after reading up on it I started by respectfully suggesting they remember this is one side of a story, by a person that has been through some stuff and is very angry. I said in cases like this, when emotions and stakes are high..
that is exactly when you should go look for an alternate view because the truth often lies "somewhere in the middle". Maybe that was risky (not to say this is all lies) but I didn't want to lose her. I then asked, with genuine curiosity/ kindness what about this video struck her?
Read 10 tweets
We found unique breast immune cells in the duct walls – ductal macrophages. They remove dying cells, help remodelling + are key players in cancer.

How did we get from this first sighting to finding their identity and function? Follow this thread!
bit.ly/35o2XSj
1/n Discovery of mammary ductal macrophagesTissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
The breast contains mammary ducts surrounded by fat, blood vessels, immune + other cells.

We use 3D imaging to investigate the complex relationships b/w these cells to better understand disease.
#microscopy #mammarygland
2/n
The ducts form a tree that branches through the breast and blooms and recedes in pregnancy and weaning. These are precancerous mouse ducts, alveoli in lactation and a summary of development in mice.
3/n Precancerous mammary ductsMicroscopic breast alveoli in lactation
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Dear scientists: now would be an amazing time for you to tweet about why Black Studies and Women’s and Gender Studies (WGS) are important to you as scientists and humans. Use the hashtags #BlackStudiesMatters #WeNeedWGS! Lift up your voices for fields that make ours better!
Without Black studies and WGS, I might not know any history of Black women in science. Both fields help me make sense of my life as a scientist and have kept me in the scientific game. #BlackStudiesMatters #WeNeedWGS
#BlackStudiesMatters because it is one of the reasons I grew up believing in my own humanity, knowing I come from a community with history that runs deeper than what white supremacy likes to teach us.
Read 5 tweets
By now, everyone is all too familiar with COVID-19, but do you understand how it actually affects your body? I made this poster to try to summarize the main events that occur following infection. I hope you learn something!
#sciart #scicomm #coronavirus #covid19
Full image can be found here: azuravesta.com/covid-19-pande…
Special shout out for @mscbmc for teaching me how to do pathological illustration! And please #sciencetwitter and #scicomm-ers let me know if there are any glaring mistakes in the information. I will be posting the full list of references on my website in the coming week.
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Starting a thread for new #SARSCoV2 ideas that we have been brainstorming amongst friends. Calling for inputs, suggestions and help getting someone to try developing in the lab if it makes sense.

First one now is a yeast/bacteria based diagnostic test

#sciencetwitter
One main constraint in current RTPCR/serology tests is supply of physical materials (RNA extraction reagents etc) and trained personnel. Need POC quick tests. What about a microbe that gives a colorimetric readout? Interested? Read on..
The virus uses both ACE2 (receptor) and TMPRSS2 (protease) to enter human cells. Presumably, and this I dont know for sure, the virus is bound to both simultaneously (atleast for some fraction of time). Critical to the idea Image
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My PhD defense was #zoombombed yesterday, so here are some suggestions for protecting your @zoom_us meetings. #virtualdefense #phdchat #ScienceTwitter 1/
Background: trolls attempted to disrupt my defense yesterday. The interruptions were harmless at first, but they became increasingly vile and threatened me. It was scary for me and all participants. 2/
Thankfully, my epic response team @jen_mckey and Shannon shut it down after like ~10min of disruption! Here's what we/they did. 3/
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For #brainawarenessweek2020 @TIMBREgroup organised to have a public event called 'Music and Consciousness'

In the following series of tweets I'm going to highlight the cognitive processes involved in how music can be used for #painmanagement

#ScienceTwitter @ME_LabTweets
New sounds in our environment can grab our attention through the orienting response so listening to any music will help to distract your attention away from your immediate environment.
However, we know that music interventions are most effective WHEN PEOPLE CHOOSE THE MUSIC THEMSELVES. Choosing a piece of music is important because you will have specific reasons for choosing the music, which makes it easier to actively listen to and engage with.
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Best software and suggestions to prepare a #poster presentation

my summary of the 80 answers received from @AcademicChatter community for the #sciencetwitter

Prepare popcorn, it's detailed but long 1/9, you can also just read the doc attached
#scicomm #STEM #phdchat
@AcademicChatter Tips 1/2
Set up a slide w/ dimensions you plan print
Keep things simpler than you first imagine
Make sure all writing can be read from no less 3-4 feet away
Use projector to test and final proofread before printing
Best posters can be digested in 2-3 minutes
Add QR code to share
@AcademicChatter Tips 2/2
Ask students for feedback
Ask someone from outside ur field for feedback
Add Twitter handle
Use online template and start adding your stuff
Start from a template that senior members of your lab have used
Submit a week before conference
Give yourself 2-3 days to print
Read 9 tweets
(1/n) Delighted to share our work using #scRNAseq to explore the intersection between regeneration, development and #immune recognition in #cancer #metastasis online @NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague
nature.com/articles/s4159…
@NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague (2/n) human primary #lungcancer is characterized by the emergence of regenerative cell types, typically seen in response to lung injury, but showing striking lineage promiscuity (identity confused!)
@NatureMedicine @sloan_kettering @WeillCornell @scell_papers @dana_peer @LabMassague (3/n) #metastasis exhibits a continuum of more primitive stem to epithelial progenitor states – driven in large part by key embryonic and lung-specifying transcription factors, SOX2 and SOX9.
Read 11 tweets
Tonight we have a special installment of #MitoMonday as @ClaireBensard hosts a #Tweetorial on her recent paper in @CellMetabolism #LateNightWithTheRutterLab
Can a specific metabolic program provoke a cell to become a cancer cell? Focusing mainly on glucose, with some thoughts on fatty acids, and glutamine, we tested the uncoupling of glycolysis and glucose oxidation to induce the transformation from stem cell to cancer cell. 2/
Long ago, Otto Warburg observed that cancer cells perform aerobic glycolysis, but we didn’t know how a cell could control flux from cytosolic glycolysis to mitochondrial glucose oxidation until the transporter was identified…bit.ly/2RDELqe #MPC 3/
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A thread about snake marks on leaves:
You must have seen marks like these 👇on leaves. I spotted this today. There is an interesting story about these marks. It was believed that the marks are left by snakes. #scicomm #sciencetwitter (1/n) ImageImage
I didn't remember the full story so I showed the image of the leaf to my mother. She immediately recognised and told me that is was believed that those leaves are cursed by snakes n should not be eaten. #scicomm #sciencetwitter (2/n)
I had heard similar story in a video on HSTP program. Farmers/sellers could not sell their vegitables if it had such marks as no one would buy it. We as kids would go search such marks on various leaves n show it 2 elders. Nobody knew what actually it was #scicomm #science (3/n)
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Thread about a mind-blowing observation I made 2day: while coming from office I saw strange nodules on a plant leaves. Out of curiosity I plucked one leaf with nodules n brought home. My guess was it must bel disease which is causing abnormal growth #scicomm #sciencetwitter (1/n) ImageImage
To check what these nodules made up of, I cut open one. I saw it was not some abnormal growth but a cavity like we see in avocado when seed is removed. And to my surprise there was a tiny insect sitting inside. I thought it must b dead but it moved.
#scicomm #sciencetwitter (2/n) ImageImage
I took the insect and put it under the Foldscope. It was beautiful animal, shot the following video. It was alive and I could see its body parts functioning.
@TeamFoldscope @PrakashLab @gubbilabs @venadavenu
#scicomm #sciencetwitter (3/n)
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I finally went through all my bookmarked tweets to compile a list of resources I want my grad students to have and wanted to (1) thank everyone who posted these resources, and (2) pay it forward and share the compiled list with all of you!
General:
Ten simple rules towards healthier research labs (journals.plos.org/ploscompbiol/a…)

Notebook for understanding journal articles (patreon.com/posts/print-yo…)

The importance of stupidity in scientific research (jcs.biologists.org/content/121/11…)
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GOOD MORNING #ScienceTwitter - hold on to your butts, b/c it's the best day of the year: #NationalSeaJellyDay! I did a thread for NSJD last year but that was before I understood how to construct threads so let's do it properly this year (1/24)
Starting off, let's take a look at how cool this alternation of generations in the typical scyphozoan jelly life cycle is: (2/24) PC: Peppermint Narwhal Creative
But why scyphozoan jellyfish - what does that even mean? There are lots of critters in the Phylum Cnidaria, separated into Classes.
Anthozoa: our anemones and corals! Like this aggregating anemone (Anthopleura elegantissima), anthozoans look like upside-down jellies (3/24) PC: South Water Stewards
Read 24 tweets

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