cancergenetics.uchicago.edu/directory/oluf…
"Cancer is a Genetic Disease/Disorder" (tonight's topic)
mycancergenome.org/content/diseas…
Chronic myeloid leukemia accounts for 0.5% of all cancer cases and 0.2% of all cancer deaths.
seer.cancer.gov/statfacts/html…
With cancer - genomic data used to help with treatment
[#breastcancer > breastcancer.org/symptoms/diagn… ]
Then ...
Germline mutations and Somatic mutations
Now a segue into BRCA1 and BRCA2 mutations.
These mutations are "relatively rare in the general population" but convey a high risk of cancer
cancer.gov/about-cancer/c…
She's said pancreatic cancer several times.
theguardian.com/law/2013/jun/1…
This was a REAL barrier. Now we have HIPPA (privacy protected).
You did not choose your genes - so genetic discrimination should not be how we manage medicine.
How to identify cancers that will kill you.
Chart shows that MRI is more successful than mammogram for BRCA-high-risk women.
BUT (I am arguing here) ... most cancers still do not have distinct genetic mutation.
A: There are times when it's not useful to know (example babies with holes in heart). The question is - when should a woman know? Risk goes up in 30s and 40s. Maybe wait until you have children.
Does a genetic mutation "make you sick"?
How will individuals use that information?
threadreaderapp.com/thread/9990964…
Dr. Olopade in 2011 (photo looks like it was taken yesterday)
news.uchicago.edu/article/2011/0…
life.wiredpen.com/2017/10/are-br…