Discover and read the best of Twitter Threads about #psc

Most recents (24)

@MondayNightIBD @BassiMehak @abbvie @JanssenUS @ferring @TakedaPharma #PreConvo #IBDPoll1⃣


25y/oM w refractory #UlcerativeColitis undergo colectomy w IPAA. Takes acetaminophen PRN headaches & drinks a🍷glass w dinner. Presents for a routine f/up visit. labs: Alk Phos 250. What is the most likely cause of this AP?
@MondayNightIBD @BassiMehak @abbvie @JanssenUS @ferring @TakedaPharma #PreConvo #IBDPoll2⃣


What is the most common extra-intestinal manifestation #EIM in patients living with #IBD?
@MondayNightIBD @BassiMehak @abbvie @JanssenUS @ferring @TakedaPharma 1/⬆️ EIMs in #IBD
⭐️ CD > UC.
⭐️ Colon involvement

💣 Pathol:
⭐️ Direct result of bowel disease (e.g kidney stone from oxalate malabsorption )
⭐️ Influx of mononuclear cells activated in the intestine➡️another organ
⭐️ Systemic Immune activation independent of gut🔥 Image
Read 8 tweets
Voy a montar un hilo sobre #urbanismo neoliberal (casi un pleonasmo) para l@s que no podáis venir mañana pero esteis interesad@s.

"El urbanismo neoliberal o la ciudad al servicio del mercado"

1.- Primero de todo habría que empezar por qué entendemos por "neoliberal". Aquí hay varias definiciones. A mi me gusta esta de David Harvey: "El neoliberalismo es, ante todo, una teoría de prácticas político-económicas que afirma que la mejor manera de promover el bienestar..."
2.- del ser humano, consiste en no restringir el libre desarrollo de las capacidades y de las libertades empresariales del individuo, dentro de un marco institucional caracterizado por derechos de propiedad privada, fuertes mercados libres y libertad de comercio...
Read 20 tweets
Geschichte meiner #LeberTransplantation #TransplantiertV
Seit 2004 ist bei mir die #Auto-Immunerkrankung #PSC (Primär sklerosierende Cholangitis) bekannt. Dies ist eine Erkrankung der Gallenwege, welche sich innerhalb der Leber befinden. Diese Krankheit führt fast immer 1/x
zur Notwendigkeit einer Lebertransplantation (#LTX). Deshalb wurde ich auch, als der Gesundheitszustand schlechter wurde für eine #Transplantation gelistet. Einige Wochen vor der LTX wurde mir mitgeteilt, dass es bald so weit wäre. Am 27.12.2018 bekam ich kurz nach 2/x
Mitternacht einen Anruf um über die Verfügbarkeit eines Organes zu informieren. Ich musste unverzüglich in die Klinik. Dort angekommen wurde ich sofort für die OP vorbereitet. Direkt vor den OP-Sälen musste ich etwas warten. Nach einiger Zeit kam dann ein Arzt und teilte mir 3/x
Read 24 tweets
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 2/ 📸 Faculty disclosures & CME certification ℹ 👇
#CME certificate 🏅 → ℹ️ Image
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 3/ 👌let's 🚴

In addition to 💉, pts w #IBD should undergo regular #PreventiveHealth #HCM:
📌Cancer Screening 🦀
📌Bone Health assessment 🦴
📌Mental Health 🥺
📌Treatment specific Testing 💉💊
📌Smoking cessation 🚬

#ICYMI vaccines #MNIBDTweetorial 📎 @🔚 of 🧵 Image
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 4/ 🧩Who is IS? #IBD pts on or had within last 3 months:
🚩 Prednisone > 20mg/day >2wks
🚩 AZA >2.5 mg/kg/day
🚩 6MP >1.5 mg/kg/day
🚩 MTX >0.4 mg/kg/week
🚩 Cyclosporine
🚩 Tacrolimus
🚩 Tofacitinib, ozanimod

🚩 Significant protein-calorie malnutrition
Read 22 tweets
It looks like the DPC's findings against the PSC card project will stand, as the Department of Social Protection has settled its appeal.

This is a massive win for citizens (and, institutionally for the DPC). Still to come- the mass action complaint by @DRIalerts against DPER.
This is, by far, the most significant decision the DPC has made following an investigation into the State. It was critical for it to win its appeal.

The Department of Social Protection has simply stalled for years in accepting the requirements of the GDPR.
If you'd like to see more on the mass complaint that was lodged by @DRIalerts, building on the now unchallenged findings of the DPC against the Public Services Card, see…
Read 24 tweets
.@welfare_ie is up before PAC at present. Lots to talk about, there'll probably be quite a bit about bogus self employment, or false self employment as the Dept's sec gen describes it. Watch it here:…
This story very well may come up too:…
John McKeon giving his opening statement
Read 27 tweets
Bien, aquí esta Gerard Esteva que se presenta como una de las 4 caras visibles de "Barcelona és imparable".

Vamos a rajar un poco de esta peña y lo que suponen👇

Gerard Esteva: “Lo que falta en Barcelona es proyecto”…
1.- Es indudable que, a todo movimiento le corresponde una reacción. Barcelona lleva ya 6 años en manos de la izquierda (quitando al #PSC) y es normal que, tras un periodo de gobierno, sea cual sea su color político, surja una oposición, más o menos articulada, en torno al mismo.
2.- En estos años hemos visto surgir diversos intentos, más o menos consolidados, de suponer dicha oposición. Desde el famoso #TsunamiVecinal, que, a propósito, es miembro también de "Barcelona és imparable", hasta la plataforma "Nosaltres, Barcelona", conformada...
Read 14 tweets
1. Congrats Dr. Heinemann and authors that evaluated the long-term post-transplant outcomes for pts with autoimmune liver diseases comparing living & deceased after brain death donor liver transplantation using the European Liver Transplant Registry. #ph260720 #AJT @amjtransplant
2. In this study, the authors studied 29902 patients from transplanted (including 1003 living donor liver transplant [LDLT] patients) for autoimmune liver diseases between 1998-2017.…
3.… After risk-adjustment, both adult and pediatric LDLT recipients had a higher hazard of death if they had primary sclerosing cholangitis (PSC). This hazard was equivalent between the graft types for other liver diseases (AIH, ALD & PBC).

#ph260720 #PSC
Read 47 tweets
Important update for #IBD. The @AmerGastroAssn has issued updated clinical practice recommendations for neoplasia surveillance in #IBD. These are not the same as "guidelines" although the difference may be mostly semantics.
Several important highlights follow
Read on!
2/ Use the newest terminology to describe a suspicious lesions as per #SCENIC: polypoid (>2.5 mm tall), non-polypoid (<2.5 mm) or invisible (avoid "flat") if detected on random biopsies, see ⬇️
Describe size, morphology, borders (v important!) and location (within/out colitis) Lesion descriptors
3/ When to start: 8-10 years after dx. Disease extent (e.g. L-sided) no longer emphasized.
a. Exception are patients with #PSC #IBD in whom you should start immediately and repeat annually
b. Use the first c/scope as an opportunity to restage
c. target severely affected areas
Read 14 tweets
@MondayNightIBD @SobiaMujtabaMD @NabilQuraishi @CholestasisDoc @DCharabaty 1/ 35 y/o M presents with fatigue & generalized pruritus x 6weeks. No skin rash, No abdo pain, diarrhea or 🩸 in stool. AST 62 ALT 64 ALP 435 Tbili 1.3. MRI/MRCP: multifocal strictures & areas of dilatation of intra +extra hepatic ducts. What’s the next step?💡 #Back2Basics #B2B
@MondayNightIBD @SobiaMujtabaMD @NabilQuraishi @CholestasisDoc @DCharabaty 2/ What’s #PSC & phenotypes?

🧩Idiopathic chronic inflam dis. of the biliary tree

🧩90%: Large ducts (LD): "Beads on string appearance” on ERCP/MRCP (pt👆)

🧩5% Small IHD only: nml MRCP, dx by liver bx, slide👇

🧩5% PSC w AIH overlap: abnl MRCP+liver bx w⬆️AST/ALT or IgG ImageImage
@MondayNightIBD @SobiaMujtabaMD @NabilQuraishi @CholestasisDoc @DCharabaty 3/ 💎#B2BPearl #PSC w ⬆️IgG4

📌15% of LD-PSC

📌⬆️IgG4 serum>140mg/dL +/- tissue
💎✅IgG4 at least once w PSC dx

📌Assoc. w AI pancreatitis; other Ig4 dis.

💎⬆️severity of UC, colectomy
📌More rapid progression to cirhhosis

💎Steroid responsive: ️ ⬇️AlPhos, TBili, IgG4
Read 15 tweets
Reports of the situation in #Mali further deteriorating.
The situation in #Mali fast developing, ECOSAS expressing concern and urging soldiers to return to their barracks
Reports coming out of Bamako, #Mali indicate that the mutiny seems to be evolving into a coup. Latest news is President Kieta has been arrested. This is sure to trigger the @_AfricanUnion #PSC AU_PSD to consider action under Art 7(1)(G) of the PSC Protocol.
Read 11 tweets
Thread. @ICCLtweet joined #TonightVMTV yesterday to discuss the #PublicServicesCard.

The Minister also appeared and said it's "difficult to have a conversation with people when they don’t even know the facts.”

Respectfully, we know the facts.…
@ICCLtweet The Minister said “Of course they have a choice” (5.52) about the PSC.

Fact: Our right “to access an ever-increasing range of public services has, in effect, been made conditional upon production of a PSC” (DPC,…, at p21)

What kind of "choice" is that?
@ICCLtweet Many have reported their lack of choice regarding the #PSC. Remember:

The person denied a pension.…

The teacher denied benefits after breaking her ankle.…

The firefighter denied a passport.…
Read 7 tweets
Minister for Employment Affairs and Social Protection @ReginaDo is up before the Oireachtas Committee on her dept in the next few mins to talk some #PSC. Her first appearance since the whole farrago broke in August. Watch it here…
@ReginaDo Nothing particularly new in the opening statement, tho it does push the PSC's genesis back to December 1993 and the Government approval of "an integrated social services system", which is fairly emblematic of the strategy of legitimising the card by dint of decades of development
Department is still waiting on @DPCIreland enforcement notice says the Minister. When that happens it will be "carefully considered" before "appropriate actions" are taken. "This may include a referral to the courts". Short'n'sweet #PSC
Read 36 tweets
John McKeon, sec gen of @welfare_ie will be before the Public Accounts Committee shortly for the first time since the #PSC was declared illegal by @DPCIreland. You can watch it here, there should be some interesting questions...…
@welfare_ie @DPCIreland Ahead of that, the committee is discussing the Dept Finance's denial of transparency re barrister costs for the Apple appeal citing GDPR, something the @DPCIreland has utterly debunked. "This sets a very worrying precedent," says @alankellylabour
@welfare_ie @DPCIreland @alankellylabour DPC getting props for its own transparent submission to the comittee in which it detailed the costs it paid out over the past year and how much the investigation into the #PSC cost
Read 47 tweets
A key question for #DataProtection watchers in Ireland today is: “How much did @DPCIreland actually get? (And how much did they look for?)”

We have had nearly 5 years of appreciable upping of DPC budget from €1.5M in 2014 to the present €15.2M. 1/n
2/n But the office is still under manned and regularly outgunned even though it is de facto regulator for much of world’s personal data. Also, comparing to the Financial Regulator pre-crash, @DPCIreland is still less than 30% the resource levels that were keeping an eye on banks
3/n However, @DPCIreland has picked a huge fight (rightly) with @IRLDeptPER over #MyGovId. But @IRLDeptPER allocates the budgets to public bodies. So, there is a HUGE risk of the independence of the Office being attacked by pulling in the purse strings.
Read 9 tweets
.@DPCIreland Helen Dixon is up in front of the Public Accounts Committee, starting now. Ostensibly to discuss the commission's accounts for 2018. However, you can also expect a certain not-a-national-ID-card to have a starring role #PSC Watch here:…
@DPCIreland Commissioner's opening statement:
@DPCIreland Sinn Fein's David Cullinane probing Dixon about when fines of €1 million under GDPR can come into play. "The DPC decides and adjudicates in terms of the fine, and the court applies fine if there is no appeal," Dixon says
Read 44 tweets
#PSC debate kicking off in the Dail, @ReginaDo up first…
@ReginaDo .@willieodeaLIVE calling strongly for sight of the Government's "incredibly strong" legal advice regarding @welfare_ie's response to the DPC report #PSC Would be very interesting indeed to see that advice
@ReginaDo @willieodeaLIVE @welfare_ie The department's response "creates the impression that if a company in future is ruled against it can enlist the aid of the government and can get that decision overturned" - O'Dea #PSC
Read 24 tweets
A general comment: DEASP are making a great deal of noise about their survey on #PSC. It's mad popular they tell us.
So is not paying taxes. We'd all love not to do that. But if you decide not to pay taxes, no matter how popular that is, Revenue have words. Popular != Legal.
Page 5: Cites some of the history of the card. That's nice. However, the debate (as @ciananbrennan has pointed out) the dail record of the debate is worth reading

And what the history ignores is that #DataProtection law has evolved since 1998.
On page 6, the Dept makes a comment that people have wanted the use of #PSC expanded. Again - perceived popularity != legal basis.

So far what I get is "this might be a good idea with merit that should have been done properly".
Read 9 tweets
A few points #PSC 1) I wonder what this new finding will be? For context, the report as to the biometric nature of the card was originally intended to form part of the main report, but has been delayed til the end of the year to give @welfare_ie a chance to respond to it, as... wasn't contained in the interim report delivered in August of last year. 2) Arguing that a finding of an independent regulator has no legal force... where do you start with that? Do they think the coming enforcement notice is also toothless? It just smacks of pure...
... distraction and spin. 3) The Acts are indeed no longer in place, as the investigation began pre-GDPR. Are they suggesting they'd sooner be investigated under GDPR? Because they'd get filleted. The whole thing is just so, so wrongheaded #PSC
Read 3 tweets
SR @Alston_UNSR, what we see around the world, governments developing surveillance systems don't subject the middle class to the issues. that 'we have problems with the poor - welfare fraud, crime etc' means the poor are very often guinea pigs for new programs.
@Alston_UNSR Per SR @Alston_UNSR what we are dealing with today is very different from what could have been envisioned a few decades ago. Tech including algorithms and machine learning, transforms conversations about issues like the public services card.
@Alston_UNSR Per SR @Alston_UNSR the fact that tech allows for greater in roads into our privacy doesn't mean that governments can act irresponsibly or unaccountably.
Read 16 tweets
Thread. The Data Protection Commissioner is before the Justice Committee right now and we expect the committee will be raising the #PublicServicesCard and the DPC’s investigation into it. Tune in here to watch:…
While waiting for the public session, I'll congratulate @thekhrc for their Moday win when Kenya’s high court suspended the mandatory roll out of NIIMS. The #NIIMSCase deals with a national identity registration system with parallel data protection concerns to the #PSC @INCLOnet
For those hoping to understand identity systems more generally, @privacyint has a handy three part explainer:…
Read 47 tweets
Read 934 tweets
Hi guys,#TGIF! 🎉💥😉

In today's #SportsLaw matters: Do you know what happens if a party who filed a Claim before #FIFA's #PSC or #DRC dies before the determination of the suit?

Right or wrong?

Our @Akinyemiesq has penned his thoughts on this. Watch this space, 7pm today. ⚽📚
Good evening, and Kick off!..

The round leather game, as fondly called, used to be a mere recreational activity which attracted some rewards by the way. However, over the last three decades or so, the commercial value of sports, particularly football, has grown astronomically.
The increase in its commercial value has occasioned a reciprocal increase in disputes between persons involved in the game; from coaches, to clubs, to players, etc.
Read 32 tweets
The State continues to be, imo, entirely disingenuous about the #psc rollout and is still pushing it through without proper legal basis or authority so that it reaches critical mass.

One thing is clear: they are avoiding any binding decisions on the PSC. #thread

📷: @DRIalerts
You might recall that, since @RSAIreland backtracked on requiring #PSC for driving licences, passports are effectively the last non-social welfare holdout on mandatory/compulsory use.

This type of requirement is what takes it from mere "token" to de facto ID card.
At every step along the way over the past 12 months or so, in my experience, the authorities have backed down when challenged. The difficulty is that they find a different, non-PSC, reason to back down.
Read 14 tweets

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