, 4 tweets, 3 min read Read on Twitter
Here are 10 cryptic clues to this diagnosis:
1. Georgina, William and Arthur
2. Chest pain
3. 17p11.2
4. Larger, lower
5. Canada
6. Face
7. No cathepsin
8. It's ok to be a man
9. Nothing in the wall
10. Epidermolysis bullosa, ichthyosis, neurofibromatosis

#pulmpath #dermpath
@kriyer68 and @ariella8 you guys are on top of your game!

Clues explained:
1. Georgina, William and Arthur (first names of Birt, Hogg and Dube)
2. Chest pain (from pneumothorax)
3. 17p11.2 (FLCN gene)
4. Larger, lower (cysts larger than LAM with predisposition for lower lobes..
Clues explained..(contd)

5. Canadian authors
6. Face (where fibrofolliculomas occur)
7. No cathepsin (cathepsin is pos in LAM not BHD)
8. It's ok to be a man (LAM is super rare in men, not BHD)
9. Nothing in the wall (unlike LAM, where cysts contain abnormal smooth ms cells)
Last clue!

10. Epidermolysis bullosa, ichthyosis, neurofibromatosis (these are genodermatoses, like Birt Hogg Dube)
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