⚠️Good news! BioCryst launched a clinical trial of its antiviral #galidesivir in patients with #COVID19.
Galidesivir has broad-spectrum activity in vitro against >20 RNA viruses, including #Ebola, MERS and #SARS (closely related to this #coronavirus).😃
finance.yahoo.com/news/biocryst-…
Galidesivir has broad-spectrum activity in vitro against >20 RNA viruses, including #Ebola, MERS and #SARS (closely related to this #coronavirus).😃
finance.yahoo.com/news/biocryst-…
#Galidesivir works similarly to #favipiravir (approved in #Japan/showed efficacy against #COVID19) & #remdesivir.
The drugs block the virus’ ability to make RNA copies needed for new viral particles, so it’s plausible they'll work against #coronavirus.🤞🏼
The drugs block the virus’ ability to make RNA copies needed for new viral particles, so it’s plausible they'll work against #coronavirus.🤞🏼
I spent years working on #galidesivir (BCX4430); we published our findings in @nature.
Like #SARS, #Ebola & influenza, the new #coronavirus uses RNA as its genetic code. Blocking the ability to copy RNA is an effective approach against other RNA viruses😃
Like #SARS, #Ebola & influenza, the new #coronavirus uses RNA as its genetic code. Blocking the ability to copy RNA is an effective approach against other RNA viruses😃
More good news: FDA can authorize the use of unapproved medicines, such as #galidesivir, #remdesivir or #favipiravir, during medical emergencies, such as the #CoronavirusPandemic.👇🏼
Cocktails of approved drugs can be used NOW (they're already approved!).
fda.gov/regulatory-inf…
Cocktails of approved drugs can be used NOW (they're already approved!).
fda.gov/regulatory-inf…
#Galidesivir showed preclinical (in vitro) activity against #SARS – *closely* related to this new #coronavirus (#SARSCoV2) – so there's a decent chance it may be effective against #COVID19.
This randomized, placebo-controlled study will soon find out!🙏🏼
nature.com/articles/natur…
This randomized, placebo-controlled study will soon find out!🙏🏼
nature.com/articles/natur…
