1. Start by defining the aim, scope, and objectives of your project, and by identifying the #biological and #computational questions you want to answer.
2. Identify the #data sources, types, and formats, that are relevant and available for your project, and evaluate their quality, quantity, and suitability.
3. Select the tools, methods, and #algorithms, that are appropriate and effective for your #project, and consider their performance, accuracy, and limitations.
4. Develop a clear and reproducible #workflow, that outlines the steps and tasks, and describes the data and tools, used in your project.
8. Use always your scientific mindset, this will guide you through great hypothesis testing, experimentation, and reproducibility, to ensure the validity, robustness, and generalizability of your results.
9. project management: #planning, #monitoring, and reporting, to ensure the timely, efficient, and effective execution of your project.
2. #Bioinformatics has many exciting applications in various fields, such as #genetics, #genomics, #proteomics, and #metabolomics, that can provide new insights into the workings of living systems, and can help to advance science and society.
2. #AlphaFold has been applied and tested extensively in the biennial #CASP (Critical Assessment of protein Structure Prediction) experiment, and has achieved state-of-the-art performance.
2. The #cloud provides a flexible and dynamic #infrastructure that can be easily adjusted to the changing needs and demands of #bioinformatics projects.
Are you interested in getting started in #bioinformatics but not sure where to begin? Here are some tips to help you get started on your journey. A THREAD🧵🧵:
Next, learn about #genomic data formats and standards, such as #FASTA, #FASTQ, and #GFF. This will allow you to effectively manipulate and analyze large-scale #genomic#datasets. The #NCBI SRA and #EBI ENA databases are great places to find real-world data to work with.