Discover and read the best of Twitter Threads about #workout

Most recents (24)

This one found that a higher-intensity aerobic exercise is more likely to elicit greater increases in circulating exercines that are known for their neuroprotective effects.
- Findings showed that Cathepsin B was enriched in the circulation in an intensity dependent manner during aerobic exercise.
- Interestingly, skeletal muscle tissue was found expresses both message and protein of Cathepsin B (CTSB) and brain derived neurotrophic factor (BDNF), with the latter being highly expressed in glycolytic skeletal muscle fibers.
Read 4 tweets
This narrative review explores the mechanisms of action and efficacy of caffeine and the potential for combinations of caffeine and other dietary compounds to exert psychological effects in excess of those expected following caffeine alone.
Key Points:
- Caffeine, when taken alone, is associated with reasonably consistent ergogenic and psychological benefits. However, its effects on mental performance are limited, and do not encompass benefits to several sport-relevant cognitive domains.
Read 8 tweets
This one suggests that age acceleration is associated with lower strength and/or loss of strength over time in US adults aged 51 years and older, followed over an 8-10 year period.
- "A growth in research evidence documents that epigenetic phenomena, such as DNA methylation (DNAm), are highly implicated in the development of disease and rate of biological ageing...

Ref:
doi.org/10.1186/s13059…
"...Given that methylation profiles are thought to be modifiable by lifestyle and other environmental factors, it has been proposed that DNAm age is a robust biological ageing clock providing a superior estimate of true biological age over chronological age...
Read 13 tweets
This study in Finnish twins finds that an unhealthy lifestyle during pubertal years (obesity, smoking, binge drinking, low levels of physical activity) is associated with accelerated biological aging in young adulthood.
- Both the class with the overall unhealthiest lifestyle and that with a high BMI were biologically 1.7–3.3 years older than the classes with healthier lifestyle patterns when DNAm GrimAge was used...
... and had 2–5 weeks/calendar year faster pace of biological aging when using DunedinPoAm.
Read 6 tweets
Using Mendelian randomization analysis and conventional analysis, this one finds fat mass to be causally and linearly associated with all-cause mortality, while showing that the obesity paradox found in observational analyses can be explained by high-risk lifestyle choices.
- The phenomenon where a higher BMI correlates with lower mortality risk has been called the obesity paradox.
- In order to investigate the association between fat mass and mortality and mortality not only among the whole population, but to be able to stratify in subgroups as well, the authors used six well-known lifestyle risk factors to assess high/low risk lifestyles.
Read 12 tweets
This one found serum klotho levels, a protein primarily produced by the kidney which is considered to be anti aging and its levels appear to increase with exercise, to be negatively associated with heart failure in middle-aged and older adults.
- Each 2.72 pg/ml increase in Klotho concentration decreased the risk of heart failure by 45% after controlling for potential covariates, and such a negative and significant association was also found in half of the subgroups.
"Our findings indicated that a higher serum Klotho concentration was significantly associated with a lower risk of HF in half of the subgroups...
Read 12 tweets
This umbrella review of meta-analyses found strong evidence to suggest that physically active individuals have a lower risk of developing Alzheimer's Disease and that exercise interventions exert numerous benefits on patients who already have Alzheimer's Disease. Image
- The present umbrella review found that there is strong evidence of a protective effect of regular physical activity against Alzheimer's Disease risk, with active individuals having a~ 30–40% lower risk compared with inactive individuals.
- "Although a dose–response association between physical activity volume and risk of dementia has been previously reported...

Ref:
doi.org/10.1136/bmjope…
Read 12 tweets
Here, physically inactive primary care patients aged between 19 and 80 years living in Spain, were more likely to have a reduced risk of mortality by increasing their physical activity, even in doses below the recommended levels.
- Physical activity levels in this inactive population of primary care patients translated into risk reductions in mortality.
- These benefits followed a clear dose–response relationship, in which mortality started to fall even with only small increases in physical activity.
Read 5 tweets
This one fails to support the notion that stretching may cause temporary decreases in muscle strength if performed before athletic events or exercise, in young, male individuals.
- The study aimed to compare the acute effects of 2-, 4-, and 8- minutes of intermittent intermittent static stretching on isometric maximum voluntary contraction force of the hamstring and calf groups of muscles.
- Each visit was separated by a gap of at least 3 to 4 days so that the effects of one stretching do not persist until the day for the next stretching.
Read 9 tweets
This one found that spending a greater amount of time in physical activity, but not a healthy diet, may be associated with greater cortical thickness, in youth and young adults (but not in children).
- Children between the ages of 7–11 years old with prenatal exposure to gestational diabetes mellitus, and college students aged 16–35 years old were included in the study.
- Overall physical activity was positively associated with cortical thickness in the caudal medial frontal cortex and the cuneus cortex.
Read 9 tweets
This one found that students attending college and universities in Ireland who adhered to both aerobic and muscle strengthening guidelines were more likely to have better measures of mental health. ImageImage
- In the study sample, 50.9% were female and were aged on average 23.17 years. White European was the most reported ethnicity (91.2%), with other ethnicities including Asian (4.3%), Black (1.9%), mixed/multiple (1.6), and other (1.1%).
- Approximately 59% of the students were found to be insufficiently active.
Read 7 tweets
Here, objectively-measured moderate and vigorous physical activity were found to be associated with lower risk of affective disorders, including depression and anxiety.
- A higher level of physical activity was associated with lower risk of affective disorders up to 500 min of moderate and 120 min of vigorous physical activity per week.
- At an equivalent amount of time, vigorous physical activity was associated with lower risk of affective disorders than moderate physical activity.
Read 9 tweets
Here, any intensity of physical activity was associated with a decrease in total cholesterol, with higher MVPA being associated with reduced SBP, whereas higher LIPA being associated with decreased measures of adiposity, in individuals with coronary heart disease.
- 72 participants (predominantly males) with a mean age of 64 years were recruited to this 12-month observational study.
- Participants were included if they had stable CHD and were receiving optimal medical treatment ± revascularisation.
Read 10 tweets
This one suggests that non- or low-responders to an exercise intervention prescribed at levels currently recommended for health may benefit by changing the exercise modality (i.e. from cardio to lifting or vice-versa).
- The aim of this article was to investigate which modality (lifting or cardio) has a greater effect on cardiovascular disease risk factors and whether the responder rate and concordance of response for change in those risk factors differs according to exercise modality.
- There was an the absence of substantial group mean changes in risk factors following either resistance or endurance training, but with a large proportion of individuals seeming to respond to either.
Read 8 tweets
This systematic review comes to the conclusion that physical activity with regular aerobic training of moderate to vigorous intensity appears to help preserve leukocyte telomere length, a biomarker of biological aging associated with several age-related diseases. Image
* Key points:
- As life-expectancy increases, lifestyle choices like exercise take on increasing importance in healthy aging.
Read 15 tweets
This systematic review and meta-analysis suggests that resistance training is likely to improve muscle strength and cardiorespiratory fitness, while being an efficient strategy that may improve anthropometric measures in adolescents with obesity.
- Some of the studies that did not reveal a decrease in body fat did not include an eating plan in the intervention protocols, which may be why this variable did not change.
Thus, it appears that a resistance training program aimed at reducing body fat in obese adolescents needs to be combined with a nutritional plan to be more effective.
Read 5 tweets
In this one, even though 6 months CrossFit training (2×60 min/week) did not improve measures of well-being in inactive adults with predominantly sitting or standing occupations, it resulted in improved mobility and strength.
- The study recruited individuals with a predominantly standing or sitting occupation that did less than two muscle and/or mobility enhancing training sessions per week prior study participation.
- After 6 months significant effects were found for mobility and strength, but not for measures of well-being.
Read 6 tweets
This one found that brain activity and related brain structures differ between triathletes and people who do not exercise regularly, suggesting that exercise might not only improve the ability of self-regulation of physical activity but also self-regulation of brain activity.
- Triathletes showed a superior ability of self-regulating their own brain activity during neurofeedback training, especially over a longer period of time.
This improved neurofeedback performance in triathletes appeared to be related to larger gray and white matter volumes of the insula and inferior frontal gyrus.
Read 4 tweets
This one found that an acute resistance exercise bout can attenuate postprandial lipemia and markers of postprandial oxidative stress.
- - Both a moderate-intensity and a high-intensity resistance exercise bout caused an increase in total nitrite/nitrate concentrations concentrations and also prevented a decrease in GSH that was noted in the resting condition.
- Moderate-intensity resistance exercise was more effective at reducing advanced oxidation protein products compared with resting conditions, as well as lowering postprandial triglycerides and cholesterol concentrations.
Read 9 tweets
This study tried to determine the molecular changes with ageing in tendons in humans (specifically, at the level of tendon protein synthesis and gene expression changes), as well as the subsequent impacts of 4 and 8 weeks of training. Image
- Changes in remodelling with exercise appeared to occur early in tendon (with few changes seen with 8 weeks of training).
- While it appeared that the older tendon was less responsive to exercise training, in terms of a molecular remodelling perspective, protein synthesis was similar for both age groups.
Read 6 tweets
This one found an inverse, independent, and graded association of cardiorespiratory fitness with mortality risk across the age spectrum (including septuagenarians and octogenarians), men, women, and all races.
- This is an analysis of more than 750,000 U.S. veterans, which included a large numbers of septuagenarians, octogenarians, African Americans, Hispanics, Native Americans, and women.
- During a median follow-up period of 10.2 years and more than 7.8 million person-years of observation, adjusted associations of CRF and mortality risk were inverse and strongly graded across the age spectrum, sex, and race.
Read 6 tweets
This study examined the effect of traditional-set vs. cluster-set structures, matched for total repetitions per session at the same relative load, during an 8-week high-load bench press training program on body composition, and measures of muscle hypertrophy and strength.
- Site-specific muscular hypertrophy of the proximal and middle regions of the pectoralis major improved to a greater extent over the intervention period in traditional compared with cluster sets.
- Cluster sets were found to increase body mass compared with traditional, with no between-group differences being observed for remaining outcomes of site-specific muscular hypertrophy or body composition.
Read 7 tweets
This systematic review and meta-analysis finds that exercise training, especially aerobic exercise, can improve NT-proBNP concentrations in patients with heart failure, irrespective of overweight/obesity status, even though the size of this effect is probably small.
- Serum levels of BNP and NT-proBNP increase in response to pathophysiological conditions such as acute HF, chronic HF, ventricular hypertrophy, cardiac ischemia, atrial fibrillation, hypertension, hypoxia, diabetes and infection.
- Higher concentrations of BNP and NT-proBNP are associated with a higher risk of morbidity and mortality.
Read 6 tweets
This systematic review and meta-analysis suggests that carbohydrate ingestion before and during resistance training allows for greater volume to be completed during sessions lasting longer than 45 min and consisting of at least 8–10 sets.
- The current systematic review and meta-analysis sought to determine if and to what degree CHO ingestion influences RT performance.
Findings:
Read 18 tweets

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