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, 7 tweets, 2 min read
Thread - Harvard epidemiologists want us to eat wholegrain fibre to reduce the risk of hepatocellular cancer. Correspondent points out this is small effect thrown up by multiple comparisons.
jamanetwork.com/journals/jamao…
Harvard epidemiologists strongly suggest we eat more polyunsaturated fat from seed oils and limit saturated fat. Mechanistically this is a well-understood risk factor for liver disease, so what is the association with HCC? 2/n
Singapore study, HCC - Compared to the lowest quartile, the hazard ratio for the highest quartile intake of omega 6 PUFA was 1.49 [(95% confidence interval (CI):1.08-2.07)] 3/n
ncbi.nlm.nih.gov/pmc/articles/P…
EPIC-Europe - no association, but no stratification by PUFA subtype 4/n
onlinelibrary.wiley.com/doi/full/10.10…
Harvard authors in NHS/HPFS - Omega-6 PUFAs (HR = 0.54, 95% CI: 0.34–0.86, Ptrend = 0.02) were inversely associated with risk of HCC. 5/n
academic.oup.com/cdn/article/3/…
The HPFS.NHS data is only an abstract, from June 2019, so we can probably expect another media blitz on this subject later this year. 6/n
And that seems to be the sum total of human epidemiology on this subject.
Animal studies continue: e.g. High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma. 7/n
researchgate.net/publication/26…
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George Henderson
@puddleg
When the legend becomes fact, print the legend - Roland Emmirich's new film of Midway looks excellent, but this screen shot of the SBD attack on Soryu from the trailer illustrates the power of myth. @johnzahorik
Note the "planes crowding the flight deck". 1/n
That the USN divebombers attacked the Japanese carriers when planes were changing armament loads on the flight decks is legend - but the IJN didn't do that, and it would have made no sense, as the carriers were also flying combat air patrols so needed to land zeros on and off.
"the Japanese carriers had no strike aircraft on their flight decks, and were nowhere near ready to launch a counterattack against the Americans when they were bombed." Jon Parshall and Tony Tully, who studied Japanese records and carrier doctrine 3/n
combinedfleet.com/MidwayBook.htm
Read 10 tweets
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George Henderson
@puddleg
Here's a thread on the concept of "causality" used in the LDL cholesterol argument, explaining why people end up at cross-purposes.
I will use the example of the recent Waiho bridge collapse. 1/-
radionz.co.nz/news/national/…
This bridge, a multi-span Bailey bridge for the engineers out there, collapsed when its supports were wrecked by rocks (and ice) driven downstream by a flood, caused by a truly massive rainfall dump. Collision with the rock was the direct "cause" of failure. 2/-
The rock is a discreet, identifiable unit, comparable with ApoB in the atherosclerosis model. The flood is comparable with excess insulin and glucose; rocks are always there, rain can just turn up. 3/-
Read 8 tweets
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George Henderson
@puddleg
Jim Mann's new study, feeding a high soybean oil (40% fat) diet to Chinese. Worsens microbial diversity or something. But anyone here could tell him soybean oil is no bueno. Commensal bacteria can only metabolise SFAs, not PUFAs.
radionz.co.nz/national/progr…
Listening to this gives you a good idea of how willing the old guard are to misrepresent our diets in order to still be able to criticise them.
It's as if Mann's a lawyer, not a doctor. He's gone well beyond trying to convince the Chinese to cut back on Amazonian soybean oil.
Good work by Jessie Mulligan bringing out the finer details of this study in the interview with Jim Mann. @radionz
Good microbes don't like lots of polyunsaturates like soy oil, that's why yoghurt has to be made with high-saturated fat dairy or coconut.
scimex.org/newsfeed/benef…
Read 4 tweets

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GreatGameIndia
@GreatGameIndia
#Thread
#populationcontrollaw is actually #Agenda21 which is British policy to reduce population of former colonies like India through various sterilization & other policies peddled through United Nations and popularised by Hollywood to effectively keep nations under their orbit.
In 1974 US National Security Council under Henry Kissinger completed classified 200-page study “National Security Study Memorandum 200: Implications of Worldwide Population Growth for US Security & Overseas Interests” advocating #populationcontrollaw for nations like India.
NSSM200 claimed that population growth in so-called Lesser Developed Countries (LDCs) like India was grave threat to US National Security & outlined covert plan to reduce population growth in nations like India through birth control & implicitly war & famine #populationcontrollaw
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MV English
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#Thread Venezuela welcomed the UN High Commissioner for Human Rights, former Chilean President, Michelle Bachelet, on June 19 of this year. During her visit, the official met with government representatives, opposition leaders, trade unions and NGOs.
The visit of Bachelet was significant based on the expectation and pressure on social media by anti-chavez spokespersons. 13 days after her visit, the report delivered at the UN was published, where the exclusion of important social and political data predominates.
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Abdullah Altamami | عبدالله التمامي
@AAltamami
#ثريد #thread

البعض سمع عن الإدراج المباشر في السوق العام Direct Listing (وليس العرض العام الأولي IPO) الذي أجرته شركة سلاك @SlackHQ الإسبوع الماضي، لكن الكثير لم يتضح له الفروقات بين الإثنين، ولماذا الإدراج المباشر زادت شعبيته في الأونة الأخيرة (كما فعلت سبوتيفي @Spotify ايضاً)
سأتكلم معكم اليوم عن الفروقات بين الإثنين: العرض العام الأولي (IPO) والإدراج المباشر (Direct Listing)، ومتى يناسب استخدام أحد منهم فوق الأخر، وما هي الميزات والعيوب لكل واحد منهم.

فلنبدأ....
١- رفع رأس المال / العرض العام الأولي IPO: يتم اصدار اسهم جديدة للشركة وطرحها للعامة، في هذه الحالة الشركة تزيد من حجم اصولها (الكاش) للإستثمار والنمو، ويرتفع رأس مالها.
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Ayla Ferrone
@AylaFerrone
#THREAD: Details from yesterday's closing arguments in the federal trial against #NXIVM leader Keith Raniere. The day began around 9:30 with AUSA Moira Penza giving the prosecution's arguments. news10.com/news/local-new…
She began by describing many known NXIVM locations in Clifton Park. Penza says 127 Grenadier Court was Allison Mack's condo where the branding of women took place with their "arms above head like a sacrifice."
2 Flintlock where she says Raniere took sexually explicit photos including those of a 15 year old. 120 Victory Way, where she says DOS witness Nicole was tied to a table, blindfolded, not knowing she was being videotaped.
Read 39 tweets
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Saiswaroopa
@Sai_swaroopa
#Thread #Kurukshetra #Analytics #Mahabharata
Started a fun project of mine today. Recording the duels of Kurukshetra war in an excel sheet in anticipation of some interesting pattern. Watch this space for interesting tidbits. Full exercise may take quite a while
Interesting Results! #Kurukshatra #Analytics. So many duels without a declared result on Day One
Could record two general battles and 26 duels on Day One. Only 6 of those duels ended decisively. Pandava side suffered horribly in the hands of Bhishma. Uttara killed in the hands of Shalya. Saving grace being Abhimanyu countering Bhishma and winning over Brihadbala #Kurukshetra
Read 432 tweets
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Sunil Deodhar
@Sunil_Deodhar
#Thread

Below are the list of institutions and projects that are sanctioned or approved, and are at various stages of completion, which being taken up as for all round development of Andhra Pradesh in addition to those mentioned in AP Reorganization Act.
#ShahExposedCBN
1. National Academy of Customs, Excise and Narcotics at Palasmudram , Anantapur district;

2.Central Institute of Plastics Engineering and Technology at Surampalli Vijayawada;

3. Asia’s first medical devices manufacturing hub atat Vishakhapatnam.
#ShahExposedCBN
4.NIOT Ocean Research facility at Thupilipallam, Nellore district

5.Regional Institute of Education, (NCERT) Nellore (land yet to allotted by state)

6.MSME Technology Centre at Pudi, Vizag

7.National Kamadhenu Breeding Centre at Chintaladevi, Nellore District;
#ShahExposedCBN
Read 9 tweets

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