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#Airborne transmission: defined as the spread of an infectious agent caused by the dissemination of droplet nuclei (#aerosols) that remain infectious when suspended in air over long distances & time. What do we know about this route for #COVID19 #SARSCoV2? A #thread 🧵
Experimental studies have generated #aerosols of infectious samples using high-powered jet nebulizers under controlled laboratory conditions. #SARSCoV2 #Covid_19 #IDtwitter
Some studies in #healthcare settings where symptomatic #COVID19 patients were cared for but where #aerosol generating procedures were not performed found #SARSCoV2 #RNA but the quantity of RNA detected was in extremely low numbers. #airborne #transmission
This is what we know so far. Further studies are needed to determine whether it is possible to detect viable #SARSCoV2 in air from #Covid_19 settings where NO procedures that generate #aerosols are performed. #airborne #transmission #IDtwitter
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#airborne #aerosols #COVID19 #SARSCoV2 #thread #Covid_19 #IDtwitter #healthcare #aerosol #RNA #transmission

More from @Vaccinologist see all

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Dr. Melvin Sanicas
@Vaccinologist
At least 7 teams are developing #SARSCoV2 #vaccines using a weakened / inactivated virus. Several existing vaccines are made this way, i.e. #measles & #polio #vaccine. Sinovac Biotech started to test an inactivated SARS-CoV-2 #COVID19 vaccine. #scicomm
At least 25 groups are working on viral-vector #SARSCoV2 #COVID19 #vaccines. A #virus such as #measles or #adenovirus is genetically engineered so it can produce #coronavirus #proteins in the body. These #viruses are weakened so they CANNOT cause disease.
At least 20 teams are using genetic instructions (#DNA or #RNA) for a #SARSCoV2 #coronavirus #protein that prompts an immune response. The nucleic acid is inserted into human cells, which churn out copies of the #virus protein; most encode the virus’s spike protein. #COVID19
Read 5 tweets
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Dr. Melvin Sanicas
@Vaccinologist
Some have suggested that detection of #SARSCoV2 antibodies could be a basis for an “immunity passport” / “risk-free certificate” that will enable individuals to return to work. Currently, there is no evidence those who have recovered from #COVID19 are protected from re-infection.
Immunity to a pathogen through natural infection is a multi-step process that usually takes place over 1-2 weeks. The body responds to a viral infection immediately with a non-specific innate response: macrophages, neutrophils, dendritic cells slow the progress of the virus.
This non-specific response is followed by an adaptive response i.e. body makes #antibodies that specifically bind to the #virus. These #antibodies are proteins called #immunoglobulins. The body also makes T-cells that recognize & eliminate other cells infected with the virus.
Read 8 tweets
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Dr. Melvin Sanicas
@Vaccinologist
A #thread on the origin of the Severe Acute Respiratory Syndrome #coronavirus-2 #SARSCoV2, the #virus causing #COVID19. SARS-CoV-2 was identified early January 2020; genetic sequence shared publicly on 11 January. #scicomm [image 감사합니다 @IBS_media] @Virologist_11 @dirgarambe
Full genetic sequence of #SARSCoV2 from early human cases & sequences of other virus isolated from human cases from China & all over the world since then show that SARS-CoV-2 has an ecological origin in #bats.
All available evidence to date suggests that #SARSCoV2 #coronavirus has a natural animal origin and is not a manipulated or constructed virus. nature.com/articles/s4159…
Read 8 tweets

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