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Next speaker is Jeffrey Weinreb on Gad retention and guidelines an update. He is a radiologist at Yale. #NKFclinicals
starts with a patient who received 60-70 MRIs with contrast (brain cancer patient) He has a blood clot he thinks may be related to gad. There are people who develop chronic symptoms after gad exposure. #NKFclinicals
Chuck Norris claims his wife was poisoned following gad toxicity. #NKFclinicals
People love to show periodic tables in lectures on Gad. Gad has 7 unpaired electrons (but you knew that). Gad looks bright on T1 weighted images. #NKFclinicals
Gadolinium salts ar very toxic. Need to chelate it so it isn't toxic.
27 million MRIs in the US/yr, about 40% with gad. #NKFclinicals
27 million MRIs in the US/yr, about 40% with gad. #NKFclinicals
Gads that are available. #NKFclinicals 
Keep your eye on had stability cyclic better than linear. Ionic more stable than non-ionic. #NKFclinicals
People are using safer agent recently #NKFclinicals
We have known since 1984 that when you give gadolinium, not all of it leaves the body. Gad remains in the brain and can be visualized. You can see it in the Dentate nucleus and globus pallidus. #NKFclinicals
Confirmed in adults and children. Could this retained Gad cause the symptoms of from Gad? FDA said no. May 2017. No restriction of use. EMA came to the same conclusionin July 2017, but they restricted use of linear agents. #NKFclinicals
