Discover and read the best of Twitter Threads about #CoV

Most recents (11)

1. 10/17/14 Gain of Function Research Pause per the WH- PAY ATTENTION to the FUNDING part 💴 👇🏽 #optics #Fauci #CYA
2. 10/21/14

St Judes Research Hospital #GainOfFunction #Covid

“Notice of partial stop work order”
NIAID contract # HHSN27220140006C

Dr. Malik Peiris from University of Hong Kong is one of the CC’d individuals

6 Projects specified in notice (closeup in last ss) EXPAND
3. 10/30/14
FOLLOW UP notice
to ST JUDES 👇🏽
“CLARIFICATION of notice to stop work order”

“Encouraging researchers to pause voluntarily”
“NIAID doesn’t have the exact details of the each experiment you are planning to conduct”
signed👇🏽
Sect Chief of Respiratory Diseases Branch
Read 22 tweets
#Covid busting nasal spray begins #UK trials

The first UK clinical trials of a #nasal spray proven to kill 99.9% of the #coronavirus that causes Covid-19 will begin on January 11th at Ashford and St Peter’s Hospitals NHS Foundation Trust, in #Surrey.
The #SaNOtize Nitric Oxide Nasal Spray (NONS) is designed to kill the virus in the upper airways, preventing it from incubating and spreading to the lungs.

The treatment, developed by SaNOtize Research and Development Corp. based in Vancouver, #Canada, proved 99.9% effective
in killing the #coronavirus in independent lab tests at Utah State University’s Antiviral Research Institute. Additional studies in rodents with COVID-19 infection showed over 95% reduction within the first day after infection.
Read 33 tweets
When were the first human #coronaviruses (CoVs) discovered and studied?

How were these viruses associated with human #disease?

It's time to learn our history about human CoVs, and the scientists and volunteers that allowed us to identify this new group of viruses.

A THREAD.
Mid-sixties: HCoV-229E and HCoV-OC43 were identified.
1. Hamre et al. (1966)
2. McIntosh et al. (1967)
3. Tyrrell et al. (1965).

Image: Tyrrell et al. (1965).
Healthy HUMAN volunteers were infected to demonstrate that 229E and OC43 resulted in a common cold.

1. Bradburne et al. (1967, 1972)
2. Hamre et al. (1966)

Image: Bradburne et al. (1967)
Read 7 tweets
A somber Doug Ford beings his rare Saturday update. "Folk the alarm bells are ringing." Says too many people aren't following the rules and more decisive action needs to be taken:
BREAKING: Premier Ford announces social gatherings will be reduced in EVERY region across the province #covid19
So caps of 10 people inside and 25 outside across Ontario for the next 28 days. #covid19
Read 10 tweets
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..." ImageImageImage
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964 ImageImageImageImage
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily. ImageImageImageImage
Read 68 tweets
Los docentes han montado en tres días un enorme aula digital en unas circunstancias tremendas, sin equipos, con brechas digitales enormes entre compañeros, trabajando 12 horas al día , con instruccciones contrarias cada media hora, con muchos alumnos sin conexión ni equipos,⬇️⬇️
aulas caídas, madres que no saben adjuntar archivos, profesores que atienden a todos sus alumnos y a los compañeros en jornadas interminables porque en su día decidieron pasar de los responsables y autoformarse.Han utilizado classroom, teams meet, zoom, jitsi, edpuzzle, forms⬇️
y por supuesto también Instagram, Facebook, Twitter , telegram y sobre todo Whatsapp. Todo lo que han podido, pedido, sabido, compartido, aprendido y también sufrido y llorado. Hay docentes que apenas han notado el cambio porque ya estaban preparados, y estos docentes cuentan⬇️
Read 7 tweets
1) Stocks to Watch 2020 - February Update THREAD

Overall, +9.75%
8 double digit gainers
3 stocks with 20%+ gains
1 even stock
5 negative returns

$ZM $SQ $WORK $CRWD $SHOP $MDB $SE $OKTA $TCEHY $STNE $PYPL $LVGO $CGC $SNAP $ROKU

chrisperruna.com/2020/01/05/sto…
2) $ZM - $105.00, up 54.32%, it has been the anti #COV-19 stock but the latest weekly candle ended in the bottom half. I still like long term but it may digest some of the YTD gains which will provide a decent entry area. Above or near the 200d would be great.
3) $SQ - $83.33, up 33.2% YTD, the stock reported solid earnings and looks poised to make a run once the market stops falling and shakes the concerns surrounding the virus. #long shares
Read 16 tweets
Recently published article on origins of #coronavirus suggests:
"The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature."
biorxiv.org/content/10.110…
however, other reports challenge this interpretation.

"Blast against viral sequence database also showed these insertion sequences widely exist in all kinds of viruses from bacteriophage, influenza, to giant eukaryotic viruses"

tandfonline.com/doi/full/10.10…
But the authors admit:

"For bat #CoV viruses to gain the gene fragments from HIV-1, it will require both viruses to co-infect the same cells. Because the host cells for bat CoV viruses and HIV-1 are different, the chance for both to exchange genetic materials is negligible."
Read 3 tweets
There is an urgent need to generate effective vaccine against #SARSCoV2. This is such an important topic, and many agencies/labs/companies are working on it. I want to open up this discussion here. Let's unite towards this goal.

Pls RT, chime in with your insights/thoughts.

1/n
Learning from previous #CoV studies, what is likely to be the correlate of protection? What vaccine approaches generate best neutralizing antibody (Ab)? How quickly does #CoV generally mutate away from Ab-mediated recognition?

2/n
What would be a good preclinical model to test vaccine efficacy against #CoV? How well do antibodies to previous #CoVs cross-react against other members including #SARSCoV1, #MERSCoV and #SARSCoV2?

3/n
Read 6 tweets
Concerning the CARONAVIRUS -

Someone got Busy , In The Lab .... If you don t know The virus , How can You Give It A Name , No Cure .... Brilliant timing ! Do you Want The Antidote of This Bug ?

The following information was provided by Timothy Webster
#Coronavirus #US #Patent Number #US7220852B1 Synthesized & Registered/Patented in 2015 [In development since 2003 {This application claims the benefit of U.S. Provisional Patent Application No. 60/465,927 filed Apr. 25, 2003,
which is incorporated herein by reference in its entirety.}]

patents.google.com/patent/US72208…

The US Coronavirus Patent #expired today 01/21/2020, the sameday the first case was announced in the U.S.
Read 19 tweets
Mr President @realDonaldTrump In 2017 Gretchen Smith @cov_Gretchen founded @codeofvets in honor of her dad. She has given her blood, sweat & tears for this cause & has not profited 1 cent. Along comes @pulte #TwitterPhilanthropy who donates & helps by sharing his fortune .....
To further assist more veterans in need & expands that into other means of assisting those in need. The reality is he used Gretchen to increase his following & has now blocked @codeofvets accusing her of “unauthorized” use of his Twitter account. It’s not “unauthorized use
When that individual give the information to use as a platform to live stream as in the case of the veteran who received a brand new vehicle that @pulte donated. @DailyMailUK posted an article that is completely inaccurate as @codeofvets is the one who made this happen.
Read 13 tweets

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