Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964




This work, including the efforts of #ZhengLiShi, was funded by (NSFC) (81290341 and 31321001). This work, including the efforts of #PeterDaszak , was funded by Foundation for the National Institutes of Health
NIAID: R01AI110964






SL-CoV.b.3.The conserved 440-bp RdRp fragment of #RaBtCoV/4991 had 89% nt identity and 95% aa identity with SL-CoV Rs672




#Baric #Daszak #ZhengLiShi #Wuhan #WIV1 #SCHO14 #RhinolophusAffinis #SARSCoV2
#COVID19


#Daszak #ZhengLiShi #coronavirus #COVID19 #WuhanInstituteVirology
#EcoHealth ➡️September 18 2013




globalbiodefense.com/2013/11/04/new…
#ACE2 #WIV1 #SH014 #WIV16




#recombinant of #WIV1 and a recent ancestor of #SARS -CoV.
Funding: NIAID R01AI110964 to #PD








the Opportunity to Utilize the #CC to Identify #Host #Genes that Contribute to Emergence of #Zoonotic #CoVs . FUNDING:
NIH under awards U19 AI109761

obamawhitehouse.archives.gov/blog/2014/10/1…


#Human Emergence. #Baric 🔸️#ZhengLiShi ➡️ ZLS provided #SHC014 #Spike sequences & #Plasmids .





#NIH U19AI109761 -
#RSB U19AI107810 ➡️National Natural Science Foundation of China Award 81290341 🔸️(ZLS)




#Coronavirus Pathogenesis and Virulence in #Young and #Aged Mouse Models of #Human Disease. ➡️ #Baric et al October 29, 2011.


rMA15 caused 100% #mortality .
#UNC #Recombinant #virus




cofactor associated with #disease severity following #SARS-CoV #infection .




🔸️#Baric et al. January 12 2007.
The #MA15 #virus will enhance the use of the mouse model for SARS because infection with this virus in mice reproduces many aspects of severe human disease.



🔸️#Baric April 29, 2020.
#VeroE6 #SHC014 #MA15 #ACE2 #UNC #GilheadSciences #SARS-MA15 #WIV1
stm.sciencemag.org/content/12/541…
"We were seeking ‘one drug for many bugs.’ When this pandemic arrived.." #Baric #Fauci
sph.unc.edu/sph-news/remde…
wunc.org/post/unc-lab-m…

chapelboro.com/news/coronavir…
ncbi.nlm.nih.gov/pmc/articles/P…