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Robert W. Yeh MD MBA @rwyeh
, 4 tweets, 3 min read Read on Twitter
BREAKING NEWS!!!

In the first ever randomized clinical trial, we demonstrated that parachutes did NOT prevent death or major injury compared to control in individuals jumping from aircraft.

Published today in @bmj_latest: bmj.com/content/363/bm…

#PARACHUTETrial #XmasBMJ
Deeply appreciative of all the efforts of all the PARACHUTE Trial Investigators.

A multicenter collaboration between @SmithBIDMC and @UM_MiCHAMP.

#XmasBMJ #PARACHUTETrial
Our editorial, behind the scenes of the trial, linked below.

N.B. to the public - please continue to use parachutes for skydiving.

blogs.bmj.com/bmj/2018/12/13…
One small jump for woman, one giant leap for evidence-based medicine....
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More from @rwyeh see all

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Interesting validation of the DAPT Score in a large real world population. I'm most interested in the authors discussion, because the data are largely consistent with everything else that has been published. It's the spin that is different here. 1/
Let's start with the validation. The DAPT score is built on 2 separate Cox models. The authors validated each one in their study. Here is how they performed: C-statistic 0.67 for ischemia and 0.67 for bleeding. That's basically how well they performed in the original cohort.
Somehow, that didn't make it to the abstract, but instead, they focused on this.
Read 11 tweets
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How could you use IV to analyze #CABANA? I haven't seen the publication (is it published?) and am going mostly on what people have tweeted. But if most of the crossover happened early, before patients experienced endpoints, then it could be pretty straightforward...
Getting randomized to ablation in the trial meant that you were very likely to get it, but not in all cases. Similarly, getting med Rx meant very likely to get med Rx, but not in all cases. So the breakdown is something like below.
If you imagine that the populations in both arms are identical (which is true on average), then for every patient in one arm, there is his/her equivalent doppleganger who is identical in all ways, except got randomized to the other arm.
Read 18 tweets

Related threads

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#BREAKING: It is now confirmed that following to an agreement between #Syrian authorities & #SDF/#YPG, #Syrian Arab Army will quickly take control of city of #Manbij upon withdrawal of last #US troops. #Russia will not provide air support, but #SAADF will establish No fly zone.
#BREAKING: Large convoy of #Syrian Arab Army waiting for withdrawal of last #US troops from #Manbij to take control of the city & not let it to be occupied by #Turkey's Ahrar al-Sharqiya terrorists (all ex-#AlQaeda). #Syria Air Defense Force has deployed Buk-M2 SAM batteries too.
These are the terrorists mobilized by #Turkey to take control of #Manbij, kill hundreds of civilians and start ethnic cleansing there. Coalition of #YPG #Syrian Arab Army will confront #FSA, Ahrar al-Sharqiya (former #AlQaeda terrorists) & Islamofascist Turkmen militias.
Read 9 tweets
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#BREAKING
US Secretary of State Mike Pompeo explaining new sanctions on #Iran.
Oil money will be going into a foreign bank account to only be used for humanitarian purposes.
These will be relentless sanctions, he added.

#SanctionsAreComing
US Treasury Secretary Steve Mnuchin
We are imposing the highest pressure on #Iran's regime. Tehran will be facing mounting isolation until they end their malign activities. We are watching the Iranian regime with laser focus.

#SanctionsAreComing
Pompeo:
We understand #Iran is a threat to the US & we are determined to stop them.
Iran's Qassem Suleimani has American blood on his hands.
Read 27 tweets
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#BREAKING
#IraqProtests Update
July 20 - Hours ago
Basra, southern #Iraq
Demonstration against poverty, corruption & embezzlement.
Iraqis are blaming #Iran's regime for their miseries.

(Interesting how Iranians are also suffering from poverty, corruption & embezzlement.)
#BREAKING
#IraqProtests Update
July 20 - Hours ago
Baghdad, #Iraq
Security forces are attacking protesters to prevent their entrance into the "Green Zone," known as the government center.
People demand immediate release of arrested protesters & firm action against corruption.
#BREAKING
#IraqProtests Update
July 20 - Hours ago
Baghdad, #Iraq
Dozens of protesters are injured as security forces open live fire & use tear gas against demonstrators.
Read 7 tweets
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#BREAKING
#IranUpdate
(1)
 July 7 - Borazjan, S #Iran
Locals are protesting severe water shortage crisis.
"Our enemy is right here, they lie & say it's America"
#IranProtests
#IranUpdate
(2)
 July 7 - Borazjan, S #Iran
Locals are protesting severe water shortage crisis & not accepting any of th epledges provided by the local police chief.
#IranProtests
#IranUpdate
(3)
 July 7 - Borazjan, S #Iran
Locals are protesting severe water shortages & chanting:
"Not Gaza. Not Lebanon. My life for Iran."
#IranProtests
Read 9 tweets
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BREAKING : United States #US and United Arab Emirates #UAE disrupt large scale currency exchange network transferring millions of dollars to #Iran’s #IRGC -Qods Force. Exchange Network CHART published by @USTreasury
home.treasury.gov/news/press-rel…
According to statement @USTreasury: “Today the US and the UAE jointly took action to disrupt an extensive currency exchange network in Iran and the UAE that has procured and transferred millions in U.S. dollar-denominated bulk cash to #Iran’s IRGC-QF) to fund its malign
activities and regional proxy groups.”
Read 14 tweets
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#BREAKING: #LEAKED recording of GOP strategy session. Unclear at this time if related to healthcare, tax policy, or basic moral aims.
#LEAKED White House junior staffers coming to an important realization:
Sean looking for bushes like:
Read 21 tweets

Trending hashtags

#EU #Putin #International #WMD #alTanf #Newsbud #Iran #Nantes #Jordan #IranDeal #BM #Erdogan #YellowVests #Trump #US #ehahaber #CNN #Nixon #Damascus #Israel #PsyOp #MccarranAct #BTleaks #Catalonians #DeepStateInPanic

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