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Cf. when my husband was contacted by @NYULangone for medical consent after I was intubated.

"Congratulations! David is eligible to be part of a special FDA drug trial - because he's experiencing life-threatening lung failure & hooked up to a ventilator."
Specifically (emphasis added): "You are agreeing to the emergency use of clazakizumab... based on a small number of patients who developed similar LIFE-THREATENING PULMONARY FAILURE [from] COVID-19."

#coronavirus #COVID19 #CoronaBoy #LatsCovid19Journal
"In these patients, a drug similar to clazakizumab showed promise as an effective treatment for PATIENTS WITH RESPIRATORY FAILURE WHO WERE LIKELY TO DIE."

He agreed; I got the drug (along w/tocilizumab).

#coronavirus #COVID19 #CoronaBoy #LatsCovid19Journal
I was also given Kevzara, hydroxychloroquine plus azithromycin, and Remdesivir. Which worked? Who knows!

As the old JFK saying goes, success has many fathers, while failure is an orphan.

#coronavirus #COVID19 #CoronaBoy #LatsCovid19Journal
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David Lat
@DavidLat
Not an #AprilFoolsDay Joke: after 17 days at @nyulangone, including 6 days on a ventilator, I’m being discharged! Here’s my final hospital bed selfie. #coronavirus #COVID19 #coronaboy #LatsCovid19Journal
Thanks to the #HealthcareHeroes here at @nyulangone who not only saved my life, but made a long hospitalization as pleasant as such an experience can be. #coronavirus #COVID19 #coronaboy #LatsCovid19Journal
Here at @nyulangone, a top academic hospital, they’re also engaging in research to help learn more about how to fight diseases like #coronavirus/#covid19; I’m participating in 2 studies. #coronaboy #LatsCovid19Journal
Read 8 tweets
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David Lat
@DavidLat
These are very conscious choices. Before he was a Twitter star and @realDonaldTrump antagonist, @gtconway3d was known as one of the best brief writers at Wachtell Lipton.
When I was a junior associate and he was a partner, I drafted part of a brief for George. I fancied myself a good writer - I won a brief-writing prize at @YaleLawSch, served on @YaleLJournal, clerked for a top judge - but GTC made my draft ten times better.
More importantly, after the brief was filed George took the time to sit down with me and explain his edits - a master class in legal writing. And on some level I find that even more impressive.
Read 4 tweets
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David Lat
@DavidLat
Thanks! I must say, though, that an extended hospital stay isn’t consistent with my normal regimen. I haven’t moisturized in 17 days - or, for that matter, showered/shaved! Can’t wait to get home, clean up. #coronavirus #COVID19 #coronaboy #LatsCovid19Journal
I asked a nurse here if there was a shower I could use. Her candor was great: “Yes, but... you’re so close to discharge, wouldn’t be you rather take a nice hot bath when you get home?” #coronavirus #COVID19 #coronaboy #LatsCovid19Journal #HospitalLife
She then offered me a bunch of wipes so I could sponge myself down that way, which I gratefully accepted. #coronavirus #COVID19 #coronaboy #LatsCovid19Journal #HospitalLife
Read 3 tweets

Related threads

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Sananda
@SanandaEmanuel
1. 𝗗𝗲𝘁𝗮𝗶𝗹𝗲𝗱 𝗶𝗻𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝗼𝗻𝘀 𝗳𝗼𝗿 𝘁𝗵𝗶𝘀 𝘀𝘁𝗮𝗴𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗵𝘂𝗺𝗮𝗻 𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻, 𝗰𝗮𝗹𝗹𝗲𝗱 𝗔𝘀𝗰𝗲𝗻𝘀𝗶𝗼𝗻.
𝗧𝗵𝗶𝘀 𝗶𝘀 𝗳𝗼𝗿 𝗘𝗩𝗘𝗥𝗬𝗢𝗡𝗘
𝗬𝗼𝘂 𝘄𝗶𝗹𝗹 𝘂𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱 𝘁𝗵𝗶𝘀 𝗲𝘃𝗲𝗻 𝗶𝗳 𝘆𝗼𝘂 𝗱𝗼 𝗻𝗼𝘁
2. 𝗰𝗼𝗻𝘀𝗶𝗱𝗲𝗿 𝘆𝗼𝘂𝗿𝘀𝗲𝗹𝗳 𝗮 𝘀𝗽𝗶𝗿𝗶𝘁𝘂𝗮𝗹 𝗽𝗲𝗿𝘀𝗼𝗻.
𝙑𝙀𝙍𝙔 𝙄𝙈𝙋𝙊𝙍𝙏𝘼𝙉𝙏

This is from the depth of my heart.

🌱🌍🌟🌈💖🌍🌱

There is a very simple way to unify the world.
It's so simple most are blind to it.

It has to do with personal
3. responsibility.
Responsibility for HOW WE actually take care of our-self.

First, we take care of our psyche (our inner being, our soul).
We do that by letting us be the full extent of who we truly are. But at the same time evolve our-self, everyday, away from all the bullshit
Read 60 tweets
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Luke Oakden-Rayner
@DrLukeOR
#Medical #AI researchers: badly performed/described cross-validation is the most common reason I recommend major revisions as a reviewer.

CV can be used to tune models and to estimate performance, but not on the same data. See this diagram for doing both.

h/t 4 pic @weina_jin
@weina_jin The weird thing about CV in AI is that you don't actually end up with a single model. You end up with k different models and sets of hyperparameters.

It allows an estimate of generalisation for a *group* of models, but that is still a step removed from a deployable system.
@weina_jin For a more detailed explanation, see the "Nested cross-validation for model assessment" section of: ncbi.nlm.nih.gov/pmc/articles/P…

and here is the blog post from @weina_jin that reminded me to tweet about this topic weina.me/nested-cross-v…
Read 5 tweets
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Katy Hayward
@hayward_katy
For the day that’s in it, here’s a thread on #consent.
Or, rather, Consent as it's being referred in the N.Ireland hiccupy-part of the #Brexit process.

@DPhinnemore & I have been working on all of this stuff. Here’s 1 article on it. More to come.

1/15
blogs.lse.ac.uk/europpblog/201…
@DPhinnemore We can all agree that consent = a good thing.
& when it comes to post-conflict NI, particularly so.
A history of mistrust & misuse of power means that making laws that work for people of all backgrounds = vital.
It's also important that democratic processes are seen to work.
2/15
@DPhinnemore There is no ‘principle’ of consent in #1998Agreement per se, but it's there in 2 main forms.

The 1st = majority consent.
No change to the constitutional status of NI without it being approved by the majority of people in NI. Hence the provision for a #borderpoll in future.

3/15
Read 16 tweets
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Srinivas KC
@srinivaskc
#life THREAD. On Subtraction.

1/ It’s simple to note: One has to subtract before adding. Give up what’s bad, before thinking about adding what’s good. True for habits, food, news and everything else.
#life 2/ We live in a world with many apparent "signals”.

We’re consuming:
- More info/news/entertainment
- More food
- More social networking
- More things to-do/work...

…than prior generations. It’s making us lazy and critically, disengaged.
#life 3/ It’s unclear what the signal to noise ratio is - it’s a function of one’s own consumption habits.

And separately, we’re prone to setting additional goals too:
- Read good books
- Eat a healthy diet
- Have fewer but better friends
- Work smart

etc.
Read 9 tweets
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#UnRedactedCopy Lori
@LJT_is_me
❤️🇺🇸#FDA Thank you so much @SGottliebFDA
Job well done ~
axios.com/fda-commission…
Read 3 tweets

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