Discover and read the best of Twitter Threads about #oral

Most recents (9)

1/N "... 0.5% povidone iodine (PVP-I) #mouthrinse/gargle for 30 s can reduce #SARSCoV2 virus infectivity to below detectable levels. PVP-I can even interrupt SARS-CoV-2 attachment to #oral & nasopharyngeal tissues & lower the viral particles in the saliva & respiratory droplets."
3/N "[... we propose immediate use of PVP-I in healthcare workers & their patients as described to minimise risk of spread of disease as an addition to currently recommended PPE used during management of #COVID19 patients.]"

#SARSCoV2 #oral #hygiene

ncbi.nlm.nih.gov/pmc/articles/P…
Read 10 tweets
👨‍🏫 Du latin au quotidien ? Eh oui, on peut facilement exploiter le lexique déjà employé par des auteurs latins plus ou moins récents.

🔍 Aujourd'hui, on s'intéresse aux couleurs de l’arc-en-ciel selon l’auteur Ammien Marcellin, un historien du IVème s. de notre ère !
⚠️ Si je précise d’emblée qu’il s’agit des couleurs de l’arc-en-ciel SELON un auteur, c’est qu’elles seront différentes des sept canoniques que l’on connaît et apprend dans notre plus tendre enfance.
👀 Entrons donc dans le détail des couleurs qu’il emploie : elles auront chacune droit à un post plus détaillé avec d’autres nuances proches. D’abord une petite phrase de latin, avant d’avoir tout un passage en traduction :
Read 16 tweets
Read 7 tweets
In our recent review on #LongCovid/PASC we bring up the possibility that dysbiosis or imbalance of host #microbiome communities (in ecosytems such as the gut, lungs, or oral cavity) might contribute to at least some LongCovid symptoms: frontiersin.org/articles/10.33…
2/ More specifically immune dysregulation driven by #SARS-CoV-2 might allow pathobionts (bacteria capable of both commensal + virulent acitivty) in the gut, mouth, or other body sites to collectively shift towards a state of imbalance + pro-inflammatory gene/metabolite expression
3/ Conversely, b/c composition + activity of the microbiome can influence host susceptibility and ongoing control of #viral pathogens, exisiting microbiome dysbiosis in a range of body sites may serve as a form of predisposition to LongCovid
Read 11 tweets
Als wäre das ganze Auftreten des FC Ingolstadt nicht schon unfair und unsportlich genug gewesen - allen voran von Trainer #Oral -, setzten sie sogar noch einen drauf:

Ersatzspieler Maximilian #Beister meinte es nötig zu haben, mit üblen Beleidigungen um sich zu werfen. #FCN
Stefan #Kutschke hat nicht nur in der Halbzeit die Schwester von Enrico #Valentini beleidigt, sondern auch noch nach Spielschluss Michael #Wiesinger mit Gewalt gedroht: "Komm hier rein und sei ein Mann." (BILD)

Dieser zeigt sogar Verständnis dafür:
#FCN #fciFCN
Auf der Pressekonferenz meinte Thomas #Oral dann noch, dass er Michael #Wiesinger einfach ins Wortfallen kann.

Dieser reagiert gelassen: "Ich bin nur happy, dass der 1. FC Nürnberg in der 2. Liga spielt nächstes Jahr."
#FCN #fciFCN
Read 4 tweets
So how safe is #Ibrutinib ?
A very relevant question given that it needs to be administered indefinitely.
41% discontinuation rate in the "real world", most d/t toxicity.

Thread [1/12]
So what are the major adverse events anyway ?
1. A fib
2. ⬆️ Risk of bleeding
3. ⬆️ Infections
4. Arthralgias
5. Htn
6. Diarrhoea
7. Pneumonitis

[2/12]
A very common concern is tox no.1 and 2 .
⬆️A .fib = anticoag for stroke prophylax. but that's when tox no.2 comes into play.
Very difficult to ⚖️ it out .
In RESONATE trial >grade 3 afib in 3% of pts.
Most events occur within 3 mts of starting #ibrutinib

[3/12]
Read 13 tweets
Nice work @drmfreire + team at @JCVenterInst! 👉 They found that local #periodontal pathogen enrichment was positively associated with high systemic inflammatory profiles in patients with Systemic #Lupus Erythematosus: biorxiv.org/content/10.110… ImageImageImageImage
Quote from paper 👉 “...the gut #microbiome, and recently the #oral microbiome, showed direct impact on SLE subjects, the complexity of chronic diseases such as #SLE is beyond isolated body compartments, and it requires the integration of host-microbial interactions.”
Also 👉 “At the center of #autoimmune pathogenesis, this study provides evidence that #inflammatory response to #microbiome controls the severity, and magnitude of the #SLE disease”
Read 4 tweets
This paper summarizes a wealth of studies which show a growing link b/t #periodontal (oral) pathogens and systemic diseases 👉 ...including cardiovascular disease, GI #cancers, diabetes, Alzheimer’s and (very importantly!) adverse pregnancy outcomes: sciencedirect.com/science/articl… Image
For example 👉 “Respiratory #pathogens isolated from dental plaque and bronchoalveolar lavage fluid from the same patients...were shown to be genetically the same, which reinforces the view that #dental plaque could serve as a significant reservoir for #respiratory pathogens”
Or this study 👉 in which oral pathogen F. nucleatum was found in higher numbers in human #colonic adenomas relative to surrounding tissues and in #stool samples from patients with colorectal carcinoma: sciencedirect.com/science/articl… Image
Read 4 tweets

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