Discover and read the best of Twitter Threads about #systematic

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Immune Responses in Envenomation and Covid

"The powerful influence of Endothelial Cells on immune function has led to hypothesise that immune dysregulation, such as seen in systemic inflammation, might be partially mediated by the endothelium. As venom compounds>
from different species can modulate EC function...this may have important implications in venom-induced systemic inflammation...
Venom from different species can induce EC perturbations, including distortions in cellular function, morphology, cytoskeletal organization, and cell>
viability. Collectively, these actions alter vascular permeability and blood vessel stability
Additionally, snake and spider venoms are highly proinflammatory in EC cultures, commonly provoking the secretion of IL-6, IL-8, monocyte chemoattractant protein-1 (MCP-1/CCL2),>
Read 42 tweets
The findings show an absence of a systematic and coordinated plot to take over these schools and an absence of any concerted and deliberate plot to promote radicalisation and violent extremism of Muslim children in these schools or elsewhere

#TrojanHorse

tandfonline.com/doi/abs/10.108…
language used to talk about the issues of “radicalisation” & “extremism” is itself the subject of considerable debate (Kundnani 2012; Lynch 2013). There is also a difficulty in understanding fully these issues cos there is a lack of an objective or universally accepted definition
As soon as the media took hold of the allegations, there was huge publicity about the promotion of extremism, radicalisation & terrorism.
At the time, the press also expressed many irrational anxieties about these Muslim majority schools (Arthur 2015). Even though, from the
Read 80 tweets
A 🧵on our new work on preclinical #FaecalMicrobiomeTransplantation studies!

A while back, I began to plan my own #FMT study.

Turns out, the literature is wildly varied but mainly it is pretty difficult to find a protocol that has all the nitty gritty detail you need.

1/
We systematically reviewed all #FMT studies (in mice) in the past decade, extracting all the methodological details they used/reported.

3/
Read 16 tweets
It's Good Friday.

As a sacrifice to Science, I'm going to criticise every single paper I've ever written, one tweet at a time.

Stay tuned..!

#ImAVeryNaughtyBoy
Paper #1: Holmes & Spence 2004 @xmodal

Criticism: A non-systematic review of selected papers, no assessment of study quality, bias, or effect sizes. The only novel thing in this paper was a long, harsh critique of Iriki et al. (1996)

#SelfCriticism

doi.org/10.1007/s10339…
Paper #2: Skaliora et al. 2004

Criticism: I contributed only one figure (#8) to this paper, but >30 neonatal rats paid the ultimate price for my crappy patch-clamping skills (only 17 cells) as an MSc student. I still feel the guilt.

#SelfCriticism

doi.org/10.1152/jn.004…
Read 60 tweets
Infektionsgefahr in #Schulen über belastete #Aerosole
Professor #Kähler schließt sich der #AITAsk Bewertung an:
"#Lüften alleine reicht nicht. Die Schulen wurden ja lange zugemacht, weil es eben nicht reicht". #twlz #kmk #rki
sueddeutsche.de/muenchen/landk…
Schulen sind mittlerweile wieder geöffnet, weitere Jahrgänge sollen folgen, dabei steigen bundesweit die Infektionszahlen. Gleichzeitig breitet sich die Mutante #B117 weiter aus. #Schulen sollen "eher" keine Pandemie-Treiber und dank #AHA+L sicher sein, sagt das #RKI. Stimmt das?
Eine erste Warnung, was ein #Superspreader im #Klassenzimmer bewirken kann und warum #Schulen sehr schnell zu einem Pandemie-Treiber werden können, zeigte das Ergebnis der #AITask-#Modellierung bereits im August 2020: Superspreader Klassenzimmer #twlz #kmk
Read 135 tweets
How to choose between a #systematic review or a #scoping review. This is a common question with our network, so for #WorldEBHCday we wanted to break it down in a #tweetorial. #EvidencetoImpact @WorldEBHCDay (1/13)
There are three questions you can ask yourself to assess which review is right for you (here is also a fun way to do this: …srightforyou.knowledgetranslation.net) (2/13)
Question 1: Do you want to use the results of your review to answer a clinically meaningful question? If yes, a #systematic review is likely the right approach. (3/13)
Read 13 tweets
On "called in" versus "called out": in fact, a true ally can tolerate being "called out" to model #learning #mindset/#growthmindset for others. Those who need everything to be done hidden/in private reveal they care more about image, optics, their own reputation.
People need to let go of this concept of "shame" or "did you just call me a racist"? Everyone has more to learn. Was just discussing with a woman who pointed out elite programs in the U.S. fulfill "diversity" quotas with "Black" from Africa rather than descendants of slaves.
The underlying issue of exploitation, specifically slavery, was #economic. The experience of personal + generational trauma + loss of generational wealth + loss of identity is a deliberate #systematic #systems approach to value extraction for economics.

wbur.org/hereandnow/201…
Read 21 tweets
Watched @ECMcLaughlin today on #ResistanceLive. I agree, if @SpeakerPelosi continues to slow roll an overarching inquiry, I too will be funding & supporting her primary opponent - I too have been montering across all social platforms and foreign #bots are using #PsyOpps to attack
#Systematic & #Sweeping: Psychological warfare is the planned tactical use of propaganda, threats, & other non-combat techniques during wars, threats of war, or periods of geopolitical unrest to mislead, intimidate, demoralize, or otherwise influence behavior of an enemy.
@Facebook & @Twitter have trumpeted initiatives designed to prevent a repeat of the #2016ElectionObstruction, yet this week is evidence of how little has changed about the way Facebook & Twitter actually operate.
Read 7 tweets

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