Discover and read the best of Twitter Threads about #coloncancer

Most recents (14)

1/12 #TumorBoardTuesday

🔬🧬Discussion on #ColonCancer and BRAFv600E disease w dMMR led by @FlavioRochaMD
➡️Here is this week's Thurs Case🎀

👉👉 Don’t forget to pick up🆓 #CME credit by answering 2 quick ❓
Now…we’re off to the races!
2/11 #TumorBoardTuesday
Thurs Case🎀

#CRC 🚫one disease!
✅Diff 🧬subtypes that define tx sensitivity
✅BRAFv600E is bad–but may be ⬆️sensitive to IO w MLH1 meth
✅Neoadj tx: 🦊FOXTROT= poss benefit, depends on subgroup
✅Keynote177: IO= way to go in dMMR!
3/12 #TumorBoardTuesday
Thurs Case🎀

Take🏠messages (cont’d):

✅ATOMIC will help answer ❓chemo/IO combo upfront is best in dMMR and BRAFv600E
✅POLEM trial also looking at adjuv IO in dMMR @shafiarahman_

📚We captured the discussion in this moment:…
Read 18 tweets
😳🤯The hour flew by & none of us noticed!!

🙏🏽 @FogacciJoao for bringing the 🇧🇷 flair to #TumorBoardTuesday & #GastricCancer!!

🏆Remember your🆓CME

Look for Case Wrap Up🎀 04/28/22

📅Mark your calendar for 05/10/22 8pm ET when @FlavioRochaMD joins our #VirtualTumorBoard!!
Remember #TumorBoardTuesday education goes beyond Twitter - we offer 🆓 CME!!

Pick up your🏆#CME & NOW #MOC(‼️) by answering quick questions regarding a case similar to @FogacciJoao’s‼️


🔗 post rationale:

#PostTest Q1️⃣ #CME #TumorBoardTuesday @MPishvaian

🤔Now that @FogacciJoao schooled us through updates on immunotherapy for #GastricCancer, how would you answer these 2 quick ❓

🧬 Which are potentially useful immunotherapy biomarkers in gastric cancer?
Read 21 tweets
Daily Bookmarks to GAVNet 02/04/2022…
Hard barriers and soft power: Study assesses outsider perceptions of border walls…
#BorderWalls, #SoftPower, #InternationalRelations, #NationSecurity, #PersonalPerception
Individually optimal choices can be collectively disastrous in COVID-19 disease control | BMC Public Health | Full Text…
#IndividualOptimalChoices, #PublicHealth, #InterventionNoncompliance, #SpreadSuppression, #ResearchResults
Read 20 tweets
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 2/ 📸 Faculty disclosures & CME certification ℹ 👇
#CME certificate 🏅 → ℹ️ Image
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 3/ 👌let's 🚴

In addition to 💉, pts w #IBD should undergo regular #PreventiveHealth #HCM:
📌Cancer Screening 🦀
📌Bone Health assessment 🦴
📌Mental Health 🥺
📌Treatment specific Testing 💉💊
📌Smoking cessation 🚬

#ICYMI vaccines #MNIBDTweetorial 📎 @🔚 of 🧵 Image
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 4/ 🧩Who is IS? #IBD pts on or had within last 3 months:
🚩 Prednisone > 20mg/day >2wks
🚩 AZA >2.5 mg/kg/day
🚩 6MP >1.5 mg/kg/day
🚩 MTX >0.4 mg/kg/week
🚩 Cyclosporine
🚩 Tacrolimus
🚩 Tofacitinib, ozanimod

🚩 Significant protein-calorie malnutrition
Read 22 tweets
Important update for #IBD. The @AmerGastroAssn has issued updated clinical practice recommendations for neoplasia surveillance in #IBD. These are not the same as "guidelines" although the difference may be mostly semantics.
Several important highlights follow
Read on!
2/ Use the newest terminology to describe a suspicious lesions as per #SCENIC: polypoid (>2.5 mm tall), non-polypoid (<2.5 mm) or invisible (avoid "flat") if detected on random biopsies, see ⬇️
Describe size, morphology, borders (v important!) and location (within/out colitis) Lesion descriptors
3/ When to start: 8-10 years after dx. Disease extent (e.g. L-sided) no longer emphasized.
a. Exception are patients with #PSC #IBD in whom you should start immediately and repeat annually
b. Use the first c/scope as an opportunity to restage
c. target severely affected areas
Read 14 tweets

THANK YOU to @KristenCiombor for leading us through a🗣️on pMMR CRC w/ dMMR liver mets

AND thank you for @fireflyann for leading our #PatientExperience 🗣️as well

👉Don’t forget your🆓#CME credit-answer 3 quick❓
Here's the postest🔗
Thursday Case🎀(Reverse jet-lag edition✈️)
(07/06 and 07/07/21)

We🗣️ #ColorectalCancer and:
✅1st line Tx for dMMR met CRC
✅✔️ing MMR status EVEN in patients with Lynch Syndrome
✅Tumor heterogeneity

We captured the🗣️in this moment:…
Thursday Case🎀
(From 07/06 and 07/07/21)

In the #PatientExperience 🗣️we added:
✅Defining the "lingo", e.g.
👉dMMR = MSI-high
👉pMMR = MS-stable
✅Ensuring tumor testing - and🗣️results w/ docs

Also captured in this moment:…
Read 18 tweets
Foods in our #diet can alter the pro-inflammatory vs anti-inflammatory milieu of the intestinal #microbiome.

See 🧵 below for the findings!


#GITwitter #GI #gut #nutrition…
🥖 🥜 🐠 🌰
Breads, legumes, fish and nuts⬇️several pro-inflammatory pathways:
🫓⬇️pathogenic growth factors & endotoxins
🫓⬇️ pathogenic E. coli, Bacteroides fragilis, parabacerioides
🫓⬆️ammonia detoxification pathway
🌰🐟 🍑🥦
Nuts, oily fish, fruit, vegetables & cereals ⬆️short-chain fatty acid producers
🫑⬆️Faecalibacterium prausnitzii, roseburia hominis, and more

Bacteria ferment fiber and pectins to acetate and butyrate.

SCFAs have anti-inflammatory effects on the mucosa!
Read 20 tweets
#ColonCancer impacts us all. Even our mighty superheroes.

A reminder:
✅ No family history->screen at 45 or 50.

✅ Family history->screen at 40 or earlier.

✅ If symptoms at ANY AGE-> colonoscopy now

✅ Don’t let #COVID19 allow u 2 delay

Wakanda Forever✊🏾
2/#ChadwickBoseman was full of grace & strength, keeping this devastating secret from public as he braved chemotherapy & other treatments to battle this disease. Pls understand that the age of onset in his case is unusually young, but we do see #coloncancer more often in Blacks
3/ Rates in adults under age 50 are also on the rise.

As we cope with an unimaginable loss— a literal super-hero— please take a moment to learn about colon cancer risk and screening.

More info here:…
Read 5 tweets
It was really sad to wake up to the news of the passing away of one of my favorite Hollywood movie icon "CHADWICK BOSEMAN" popularly known as "BLACK PANTHER".

He was reported to have died after 4 years of battling with Colon Cancer.
@DrJohnAfam @DrNgoziOnuoha @DrZobo @DrA_001 Image
Black Panther was Said to have been diagnosed of stage 3 cancer in 2016 & despite being on Chemotherapy, he managed to give us countless moment of Joy.

May his soul RIP #WakandaForever

In memory of him,we would be talking today about #ColonCancer
@aproko_doctor @trending_medic Image
What is colon or rectum cancer?

Cancer can start any place in the body. Cancer that starts in the colon or rectum is called colorectal cancer. It starts when cells in the colon or rectum grow out of control. This makes it hard for the body to work the way it should. @drpenking Image
Read 14 tweets
Chadwick Boseman died from colon cancer at 43.

I am sad that this talented brother lost his earthly life to this disease at such a young age.

Most of us don't know the details of the screening, diagnosis, and treatment journey he endured.
What I do know is that according to the @AmericanCancer, colon cancer screening is recommended starting at age 45.

I also know that Black people suffer disproportionate health inequities related to colon cancer compared to other races/ethnicities.
We suffer these inequities not just because "we don't screen as much," but due to issues with access to care, insurance, public health outreach, and provider bias.

The same factors that drive racial health inequities from #COVID19, #HIV, and numerous other health conditions.
Read 11 tweets
So Chadwick Boseman passed from colon cancer at the age of 43.

I think this is an opportunity for Black healthcare providers to discuss the importance of knowing your family history of disease.

If he was 39 when he was diagnosed that means if he had children, they need to be
screened beginning at age 29 and any siblings he may have should also be screened if they have not been.

The general distrust Black people have for the institutions in this country is warranted. How as a Black healthcare provider do I plan to change this? I’m not sure yet, but
it is my hope that the mere act of seeing a Black doctor walk into their room to treat them will help. I CANNOT wait to champion and advocate for my future patients.
Read 6 tweets
Tonight we have a special installment of #MitoMonday as @ClaireBensard hosts a #Tweetorial on her recent paper in @CellMetabolism #LateNightWithTheRutterLab
Can a specific metabolic program provoke a cell to become a cancer cell? Focusing mainly on glucose, with some thoughts on fatty acids, and glutamine, we tested the uncoupling of glycolysis and glucose oxidation to induce the transformation from stem cell to cancer cell. 2/
Long ago, Otto Warburg observed that cancer cells perform aerobic glycolysis, but we didn’t know how a cell could control flux from cytosolic glycolysis to mitochondrial glucose oxidation until the transporter was identified… #MPC 3/
Read 23 tweets
Mayor @SylvesterTurner joins the fight for colon cancer awareness and mentions his own experience with screening in 2017. African American men are dying of colon cancer at a higher rate in @HoustonTX. This is a preventable disease. Get tested! Image
The lights of city hall were turned blue Monday and Tuesday night for colon cancer awareness. More than 50 businesses and organizations will turn their buildings blue during the month of March to encourage people to@get screened. Colon cancer is a preventable disease. Image
Mayor @SylvesterTurner stood with colon cancer survivor Allison Rosen, health professionals and Cindy Ramon, whose @houstonpolice officer husband, Norbert, died of colon cancer. He continued working during Harvey, while undergoing treatment.
Please get screened. #ColonCancer Image
Read 3 tweets

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