Discover and read the best of Twitter Threads about #coloncancer
Most recents (17)
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance 1/22 #TumorBoardTuesday #ColonCancerAwarenessMonth #OncTwitter @shafiarahman_
62 yo 👨🏼🦳 asymptomatic
🔦 Screening colonoscopy - sigmoid mass
🔬Biopsy + for pMMR/MSS adenocarcinoma
🩻Staging CT + for unresectable liver mets
🤨What first line systemic treatment would you choose?
62 yo 👨🏼🦳 asymptomatic
🔦 Screening colonoscopy - sigmoid mass
🔬Biopsy + for pMMR/MSS adenocarcinoma
🩻Staging CT + for unresectable liver mets
🤨What first line systemic treatment would you choose?
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ 2/22 #TumorBoardTuesday @MPishvaian @JohnEbbenMDPhD #CRCAwarenessMonth
👨🏼🦳started on first line FOLFOX
🧪NGS testing
KRAS/BRAF WT
TMB low
ERBB2 negative
ATM mutation
👨🏼🦳started on first line FOLFOX
🧪NGS testing
KRAS/BRAF WT
TMB low
ERBB2 negative
ATM mutation
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ 3/22 #TumorBoardTuesday #GI23 #CRCAwareness
👩🏻🏫Mini tweetorial 1👨🏻🏫
↩️Left side tumors more common:
BRAF WT
KRAS WT
HER2 amp
↪️Right side tumors enriched for
BRAF V600E mutation
KRAS Mut
MSI-H
📚@ASCO
👩🏻🏫Mini tweetorial 1👨🏻🏫
↩️Left side tumors more common:
BRAF WT
KRAS WT
HER2 amp
↪️Right side tumors enriched for
BRAF V600E mutation
KRAS Mut
MSI-H
📚@ASCO
1) Welcome to a new #accredited #tweetorial, "Utilizing Immunohistochemistry Testing, Biomarkers, and Targeted Therapeutics to Optimize Outcomes in Patients with NSCLC," featuring the highlights of a symposium presented at the #ESMOIO22 congress.
@myESMO #LCSM #FOAMed
@myESMO #LCSM #FOAMed
2) The faculty for this outstanding program were @peters_solange (Chair) 🇨🇭, @HosseinBorghaei 🇺🇸, Natasha Leighl MD 🇨🇦, and @dplanchard 🇫🇷. A truly international roster of experts in #oncology!
Don't miss prior accredited courses in this space at oncologytweetorials-ce.com/category/lung-….
Don't miss prior accredited courses in this space at oncologytweetorials-ce.com/category/lung-….
3) This program is supported by an educational grant from Sanofi. Statement of accreditation and author disclosures are at oncologytweetorials-ce.com/disclosures/.
1/ A $PVCT THREAD: (3) Potential 2023 read outs of preclinical data from sponsored research programs (#SRAs) in different diseases. #research. #oncology #hematology #dermatology #InfectiousDiseases #ophthalmology #WoundHealing #TissueRegeneration. #rosebengal #rosebengalsodium.
3/ In 2023, $PVCT expects research collaborators at different academic medical institutions to read out data from their preclinical research work under newly established and existing #SRAs. #research. #rosebengal #rosebengalsodium.
1/12 #TumorBoardTuesday
🔬🧬Discussion on #ColonCancer and BRAFv600E disease w dMMR led by @FlavioRochaMD
➡️Here is this week's Thurs Case🎀
👉👉 Don’t forget to pick up🆓 #CME credit by answering 2 quick ❓
ALL CME 🔗: integrityce.com/tbt
Now…we’re off to the races!
🔬🧬Discussion on #ColonCancer and BRAFv600E disease w dMMR led by @FlavioRochaMD
➡️Here is this week's Thurs Case🎀
👉👉 Don’t forget to pick up🆓 #CME credit by answering 2 quick ❓
ALL CME 🔗: integrityce.com/tbt
Now…we’re off to the races!
2/11 #TumorBoardTuesday
Thurs Case🎀
Take🏠messages:
#CRC 🚫one disease!
✅Diff 🧬subtypes that define tx sensitivity
✅BRAFv600E is bad–but may be ⬆️sensitive to IO w MLH1 meth
✅Neoadj tx: 🦊FOXTROT= poss benefit, depends on subgroup
✅Keynote177: IO= way to go in dMMR!
Thurs Case🎀
Take🏠messages:
#CRC 🚫one disease!
✅Diff 🧬subtypes that define tx sensitivity
✅BRAFv600E is bad–but may be ⬆️sensitive to IO w MLH1 meth
✅Neoadj tx: 🦊FOXTROT= poss benefit, depends on subgroup
✅Keynote177: IO= way to go in dMMR!
3/12 #TumorBoardTuesday
Thurs Case🎀
Take🏠messages (cont’d):
✅ATOMIC will help answer ❓chemo/IO combo upfront is best in dMMR and BRAFv600E
✅POLEM trial also looking at adjuv IO in dMMR @shafiarahman_
📚We captured the discussion in this moment: twitter.com/i/events/15212…
Thurs Case🎀
Take🏠messages (cont’d):
✅ATOMIC will help answer ❓chemo/IO combo upfront is best in dMMR and BRAFv600E
✅POLEM trial also looking at adjuv IO in dMMR @shafiarahman_
📚We captured the discussion in this moment: twitter.com/i/events/15212…
😳🤯The hour flew by & none of us noticed!!
🙏🏽 @FogacciJoao for bringing the 🇧🇷 flair to #TumorBoardTuesday & #GastricCancer!!
🏆Remember your🆓CME
Look for Case Wrap Up🎀 04/28/22
📅Mark your calendar for 05/10/22 8pm ET when @FlavioRochaMD joins our #VirtualTumorBoard!!
🙏🏽 @FogacciJoao for bringing the 🇧🇷 flair to #TumorBoardTuesday & #GastricCancer!!
🏆Remember your🆓CME
Look for Case Wrap Up🎀 04/28/22
📅Mark your calendar for 05/10/22 8pm ET when @FlavioRochaMD joins our #VirtualTumorBoard!!
Remember #TumorBoardTuesday education goes beyond Twitter - we offer 🆓 CME!!
Pick up your🏆#CME & NOW #MOC(‼️) by answering quick questions regarding a case similar to @FogacciJoao’s‼️
🔗ALL CME: integrityce.com/tbt
🔗 post rationale: bit.ly/3kcIXdv
🇧🇷🎁🇧🇷
Pick up your🏆#CME & NOW #MOC(‼️) by answering quick questions regarding a case similar to @FogacciJoao’s‼️
🔗ALL CME: integrityce.com/tbt
🔗 post rationale: bit.ly/3kcIXdv
🇧🇷🎁🇧🇷
#PostTest Q1️⃣ #CME #TumorBoardTuesday @MPishvaian
🤔Now that @FogacciJoao schooled us through updates on immunotherapy for #GastricCancer, how would you answer these 2 quick ❓
🧬 Which are potentially useful immunotherapy biomarkers in gastric cancer?
🤔Now that @FogacciJoao schooled us through updates on immunotherapy for #GastricCancer, how would you answer these 2 quick ❓
🧬 Which are potentially useful immunotherapy biomarkers in gastric cancer?
Daily Bookmarks to GAVNet 02/04/2022 greeneracresvaluenetwork.wordpress.com/2022/02/04/dai…
Hard barriers and soft power: Study assesses outsider perceptions of border walls
phys.org/news/2022-01-h…
#BorderWalls, #SoftPower, #InternationalRelations, #NationSecurity, #PersonalPerception
phys.org/news/2022-01-h…
#BorderWalls, #SoftPower, #InternationalRelations, #NationSecurity, #PersonalPerception
Individually optimal choices can be collectively disastrous in COVID-19 disease control | BMC Public Health | Full Text
bmcpublichealth.biomedcentral.com/articles/10.11…
#IndividualOptimalChoices, #PublicHealth, #InterventionNoncompliance, #SpreadSuppression, #ResearchResults
bmcpublichealth.biomedcentral.com/articles/10.11…
#IndividualOptimalChoices, #PublicHealth, #InterventionNoncompliance, #SpreadSuppression, #ResearchResults
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 2/ 📸 Faculty disclosures & CME certification ℹ 👇
#CME certificate 🏅 → ℹ️ bit.ly/3GOowNG
#CME certificate 🏅 → ℹ️ bit.ly/3GOowNG
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 3/ 👌let's 🚴
In addition to 💉, pts w #IBD should undergo regular #PreventiveHealth #HCM:
📌Cancer Screening 🦀
📌Bone Health assessment 🦴
📌Mental Health 🥺
📌Treatment specific Testing 💉💊
📌Nutrition
📌Smoking cessation 🚬
#ICYMI vaccines #MNIBDTweetorial 📎 @🔚 of 🧵
In addition to 💉, pts w #IBD should undergo regular #PreventiveHealth #HCM:
📌Cancer Screening 🦀
📌Bone Health assessment 🦴
📌Mental Health 🥺
📌Treatment specific Testing 💉💊
📌Nutrition
📌Smoking cessation 🚬
#ICYMI vaccines #MNIBDTweetorial 📎 @🔚 of 🧵
@MondayNightIBD @DCharabaty @JanssenUS @pfizer @TakedaPharma 4/ 🧩Who is IS? #IBD pts on or had within last 3 months:
🚩 Prednisone > 20mg/day >2wks
🚩 AZA >2.5 mg/kg/day
🚩 6MP >1.5 mg/kg/day
🚩 MTX >0.4 mg/kg/week
🚩 Cyclosporine
🚩 Tacrolimus
🚩 Tofacitinib, ozanimod
🚩 TNFi, UST
Also:
🚩 Significant protein-calorie malnutrition
🚩 Prednisone > 20mg/day >2wks
🚩 AZA >2.5 mg/kg/day
🚩 6MP >1.5 mg/kg/day
🚩 MTX >0.4 mg/kg/week
🚩 Cyclosporine
🚩 Tacrolimus
🚩 Tofacitinib, ozanimod
🚩 TNFi, UST
Also:
🚩 Significant protein-calorie malnutrition
1/
Important update for #IBD. The @AmerGastroAssn has issued updated clinical practice recommendations for neoplasia surveillance in #IBD. These are not the same as "guidelines" although the difference may be mostly semantics.
Several important highlights follow
Read on!
Important update for #IBD. The @AmerGastroAssn has issued updated clinical practice recommendations for neoplasia surveillance in #IBD. These are not the same as "guidelines" although the difference may be mostly semantics.
Several important highlights follow
Read on!
2/ Use the newest terminology to describe a suspicious lesions as per #SCENIC: polypoid (>2.5 mm tall), non-polypoid (<2.5 mm) or invisible (avoid "flat") if detected on random biopsies, see ⬇️
Describe size, morphology, borders (v important!) and location (within/out colitis)
Describe size, morphology, borders (v important!) and location (within/out colitis)
#APC #TumorBoardTuesday #GITwitter #LiverTwitter #PrecisionMedicine #ColonCancer #oncology @ASCO @TumorBoardTues @CCAlliance @GeneticsSociety #Genetics #Genomics
Many of the mutations happen in the MCR region, WE should investigate the Armadillo Repeats regions for therapeutics
Many of the mutations happen in the MCR region, WE should investigate the Armadillo Repeats regions for therapeutics
#TumorBoardTuesday
THANK YOU to @KristenCiombor for leading us through a🗣️on pMMR CRC w/ dMMR liver mets
AND thank you for @fireflyann for leading our #PatientExperience 🗣️as well
👉Don’t forget your🆓#CME credit-answer 3 quick❓
Here's the postest🔗
surveymonkey.com/r/DMN786G
THANK YOU to @KristenCiombor for leading us through a🗣️on pMMR CRC w/ dMMR liver mets
AND thank you for @fireflyann for leading our #PatientExperience 🗣️as well
👉Don’t forget your🆓#CME credit-answer 3 quick❓
Here's the postest🔗
surveymonkey.com/r/DMN786G
#TumorBoardTuesday
Thursday Case🎀(Reverse jet-lag edition✈️)
(07/06 and 07/07/21)
We🗣️ #ColorectalCancer and:
✅1st line Tx for dMMR met CRC
✅✔️ing MMR status EVEN in patients with Lynch Syndrome
✅Tumor heterogeneity
We captured the🗣️in this moment:
twitter.com/i/events/14131…
Thursday Case🎀(Reverse jet-lag edition✈️)
(07/06 and 07/07/21)
We🗣️ #ColorectalCancer and:
✅1st line Tx for dMMR met CRC
✅✔️ing MMR status EVEN in patients with Lynch Syndrome
✅Tumor heterogeneity
We captured the🗣️in this moment:
twitter.com/i/events/14131…
#TumorBoardTuesday
Thursday Case🎀
(From 07/06 and 07/07/21)
In the #PatientExperience 🗣️we added:
✅Defining the "lingo", e.g.
👉dMMR = MSI-high
👉pMMR = MS-stable
✅Ensuring tumor testing - and🗣️results w/ docs
✅Scanxiety
Also captured in this moment:
twitter.com/i/events/14132…
Thursday Case🎀
(From 07/06 and 07/07/21)
In the #PatientExperience 🗣️we added:
✅Defining the "lingo", e.g.
👉dMMR = MSI-high
👉pMMR = MS-stable
✅Ensuring tumor testing - and🗣️results w/ docs
✅Scanxiety
Also captured in this moment:
twitter.com/i/events/14132…
Foods in our #diet can alter the pro-inflammatory vs anti-inflammatory milieu of the intestinal #microbiome.
See 🧵 below for the findings!
🥬🍑🍅🍠🥚🍎🧀🍆🫒🫓🍇🥦🥑🥥🥯🌶️🧄🥖
#GITwitter #GI #gut #nutrition
gut.bmj.com/content/early/…
See 🧵 below for the findings!
🥬🍑🍅🍠🥚🍎🧀🍆🫒🫓🍇🥦🥑🥥🥯🌶️🧄🥖
#GITwitter #GI #gut #nutrition
gut.bmj.com/content/early/…
🥖 🥜 🐠 🌰
Breads, legumes, fish and nuts⬇️several pro-inflammatory pathways:
🫓⬇️pathogenic growth factors & endotoxins
🫓⬇️ pathogenic E. coli, Bacteroides fragilis, parabacerioides
🫓⬆️ammonia detoxification pathway
Breads, legumes, fish and nuts⬇️several pro-inflammatory pathways:
🫓⬇️pathogenic growth factors & endotoxins
🫓⬇️ pathogenic E. coli, Bacteroides fragilis, parabacerioides
🫓⬆️ammonia detoxification pathway
🌰🐟 🍑🥦
Nuts, oily fish, fruit, vegetables & cereals ⬆️short-chain fatty acid producers
🫑⬆️Faecalibacterium prausnitzii, roseburia hominis, and more
Bacteria ferment fiber and pectins to acetate and butyrate.
SCFAs have anti-inflammatory effects on the mucosa!
Nuts, oily fish, fruit, vegetables & cereals ⬆️short-chain fatty acid producers
🫑⬆️Faecalibacterium prausnitzii, roseburia hominis, and more
Bacteria ferment fiber and pectins to acetate and butyrate.
SCFAs have anti-inflammatory effects on the mucosa!
#ColonCancer impacts us all. Even our mighty superheroes.
A reminder:
✅ No family history->screen at 45 or 50.
✅ Family history->screen at 40 or earlier.
✅ If symptoms at ANY AGE-> colonoscopy now
✅ Don’t let #COVID19 allow u 2 delay
Wakanda Forever✊🏾
#ChadwickBoseman
A reminder:
✅ No family history->screen at 45 or 50.
✅ Family history->screen at 40 or earlier.
✅ If symptoms at ANY AGE-> colonoscopy now
✅ Don’t let #COVID19 allow u 2 delay
Wakanda Forever✊🏾
#ChadwickBoseman
2/#ChadwickBoseman was full of grace & strength, keeping this devastating secret from public as he braved chemotherapy & other treatments to battle this disease. Pls understand that the age of onset in his case is unusually young, but we do see #coloncancer more often in Blacks
3/ Rates in adults under age 50 are also on the rise.
As we cope with an unimaginable loss— a literal super-hero— please take a moment to learn about colon cancer risk and screening.
More info here: nytimes.com/2017/03/16/wel…
As we cope with an unimaginable loss— a literal super-hero— please take a moment to learn about colon cancer risk and screening.
More info here: nytimes.com/2017/03/16/wel…
It was really sad to wake up to the news of the passing away of one of my favorite Hollywood movie icon "CHADWICK BOSEMAN" popularly known as "BLACK PANTHER".
He was reported to have died after 4 years of battling with Colon Cancer.
@DrJohnAfam @DrNgoziOnuoha @DrZobo @DrA_001
He was reported to have died after 4 years of battling with Colon Cancer.
@DrJohnAfam @DrNgoziOnuoha @DrZobo @DrA_001
Black Panther was Said to have been diagnosed of stage 3 cancer in 2016 & despite being on Chemotherapy, he managed to give us countless moment of Joy.
May his soul RIP #WakandaForever
In memory of him,we would be talking today about #ColonCancer
@aproko_doctor @trending_medic
May his soul RIP #WakandaForever
In memory of him,we would be talking today about #ColonCancer
@aproko_doctor @trending_medic
What is colon or rectum cancer?
Cancer can start any place in the body. Cancer that starts in the colon or rectum is called colorectal cancer. It starts when cells in the colon or rectum grow out of control. This makes it hard for the body to work the way it should. @drpenking
Cancer can start any place in the body. Cancer that starts in the colon or rectum is called colorectal cancer. It starts when cells in the colon or rectum grow out of control. This makes it hard for the body to work the way it should. @drpenking
1/
Chadwick Boseman died from colon cancer at 43.
I am sad that this talented brother lost his earthly life to this disease at such a young age.
Most of us don't know the details of the screening, diagnosis, and treatment journey he endured.
#ColonCancer
#SaturdayThoughts
Chadwick Boseman died from colon cancer at 43.
I am sad that this talented brother lost his earthly life to this disease at such a young age.
Most of us don't know the details of the screening, diagnosis, and treatment journey he endured.
#ColonCancer
#SaturdayThoughts
2/
What I do know is that according to the @AmericanCancer, colon cancer screening is recommended starting at age 45.
I also know that Black people suffer disproportionate health inequities related to colon cancer compared to other races/ethnicities.
What I do know is that according to the @AmericanCancer, colon cancer screening is recommended starting at age 45.
I also know that Black people suffer disproportionate health inequities related to colon cancer compared to other races/ethnicities.
So Chadwick Boseman passed from colon cancer at the age of 43.
I think this is an opportunity for Black healthcare providers to discuss the importance of knowing your family history of disease.
If he was 39 when he was diagnosed that means if he had children, they need to be
I think this is an opportunity for Black healthcare providers to discuss the importance of knowing your family history of disease.
If he was 39 when he was diagnosed that means if he had children, they need to be
screened beginning at age 29 and any siblings he may have should also be screened if they have not been.
The general distrust Black people have for the institutions in this country is warranted. How as a Black healthcare provider do I plan to change this? I’m not sure yet, but
The general distrust Black people have for the institutions in this country is warranted. How as a Black healthcare provider do I plan to change this? I’m not sure yet, but
it is my hope that the mere act of seeing a Black doctor walk into their room to treat them will help. I CANNOT wait to champion and advocate for my future patients.
Tonight we have a special installment of #MitoMonday as @ClaireBensard hosts a #Tweetorial on her recent paper in @CellMetabolism #LateNightWithTheRutterLab
Can a specific metabolic program provoke a cell to become a cancer cell? Focusing mainly on glucose, with some thoughts on fatty acids, and glutamine, we tested the uncoupling of glycolysis and glucose oxidation to induce the transformation from stem cell to cancer cell. 2/
Long ago, Otto Warburg observed that cancer cells perform aerobic glycolysis, but we didn’t know how a cell could control flux from cytosolic glycolysis to mitochondrial glucose oxidation until the transporter was identified…bit.ly/2RDELqe #MPC 3/
Mayor @SylvesterTurner joins the fight for colon cancer awareness and mentions his own experience with screening in 2017. African American men are dying of colon cancer at a higher rate in @HoustonTX. This is a preventable disease. Get tested!
The lights of city hall were turned blue Monday and Tuesday night for colon cancer awareness. More than 50 businesses and organizations will turn their buildings blue during the month of March to encourage people to@get screened. Colon cancer is a preventable disease.
Mayor @SylvesterTurner stood with colon cancer survivor Allison Rosen, health professionals and Cindy Ramon, whose @houstonpolice officer husband, Norbert, died of colon cancer. He continued working during Harvey, while undergoing treatment.
Please get screened. #ColonCancer
Please get screened. #ColonCancer
