Discover and read the best of Twitter Threads about #livercancer

Most recents (9)

1/ A $PVCT THREAD: (3) Potential 2023 read outs of preclinical data from sponsored research programs (#SRAs) in different diseases. #research. #oncology #hematology #dermatology #InfectiousDiseases #ophthalmology #WoundHealing #TissueRegeneration. #rosebengal #rosebengalsodium.
2/ $PVCT 2023 Stockholder Letter (released January 9th). . #rosebengal #rosebengalsodium.
3/ In 2023, $PVCT expects research collaborators at different academic medical institutions to read out data from their preclinical research work under newly established and existing #SRAs. #research. #rosebengal #rosebengalsodium.
Read 60 tweets
Delighted to share our new study… introducing PhasED-Seq out today @NatureBiotech.
A fantastic collaboration from @StanfordMedicine led by Dave_Kurtz & Joanne Soo with @max_diehn to help transform #cancer interception & monitoring by improving #LiquidBiopsy #ctDNA detection of #MRD.
For many cancers & nearly all currently available techniques, the impressive KM plots of #ctDNA #MRD immediately after definitive Rx w/ curative-intent unfortunately still miss ~50% of all events which occur in the MRD-negative subset, thus having modest NPV.
Read 21 tweets
Study with amazing results: the risk of #LiverCancer after SVR is lower in #HIV/#HCV-coinfected patients than in #HCV-monoinfected ones. It is a cohort study and, despite potential biases were addressed in depth, they cannot be completely ruled out (1)
Since this is the only study design to analyze this issue, replication of this finding from other cohorts would be very welcome. If so, a number of speculations on the role of specific features inherent to HIV infection (ART, inflammation, epigenetic changes, etc) come up (2).
In the ANRS CIRVIR and ANRS HEPAVIH Study a trend to lower incidence of #LiverCancer was also observed, but without reaching the level of statistical significance (and 3).…
Read 3 tweets

1. Affects your liver
2. Extremely infectious
3. Many show no symptoms
4. Vaccine protects you
5. Can be treated
6. You can live a long, productive life with #HepatitisB infection if you treated.

A thread 🧵

{RT for awareness!} Image
First, #HepatitisB, like other viral hepatitis, loves the #liver.

Once infected, the virus goes straight to your liver, multiplies alarmingly, & tries to evade immune attacks.
In some, immune system clears the virus so they recover. In others, no, so they remain infected. Image
People who remain infected with #hepatitisB over a long period of time may develop liver issues.
Such liver problems may include #fibrosis, #cirrhosis, #livercancer, & #liverfailure.
If not detected & treated on time, the person may die of these complications. Image
Read 17 tweets
This is how the liver looks in the final stages of alcohol liver disease - #cirrhosis.

At this point of no return, liver functions worsen permanently & one barely survives a couple more years.

#AlcoholKills #AlcoholBan #Alcoholism

{Share for awareness!}
Alcohol destroys your liver in stages.

First, it causes fats to deposit on your liver.

Then, fibrous strands grow in your liver.

Finally, #cirrhosis sets it, which is irreparable & irreversible injury. It can kill you or further lead to #LiverCancer.

#AlcoholKills #AlcoholBan Image
As you drink too much alcohol, your liver & life are gradually paying the ultimate price.

So, think about this. Is it really worth it?

#AlcoholKills #AlcoholBan
Read 3 tweets
In this thread, I will compile my medical illustrations in oncology and #RadOnc.

Many are from textbook w @DanTrifMD…
based on @ARRO_org study guide for board exams.

A picture is worth 1000 words.
Here is oncology in a few pics.
@DanTrifMD @ARRO_org @SpringerNature Starting with pediatrics:
Rhabdomyosarcoma treatment paradigm for cancers of head/neck depends on parameningeal vs non-parameningeal location. PM is an unfavorable site, affects stage. #sarcoma #HNCSM
@DanTrifMD @ARRO_org @SpringerNature CNS/brain anatomy from sagittal view.
Chapter from @cgr0105, Sameer Nath, from University of Colorado
Read 49 tweets
Liver stiffness at the time of sustained virological response predicts clinical outcome in #HIV\#HCV coinfected patients treated with DAA. LS <14 kPa at this time-point is associated with very low risk of subsequent decompendation and #livercancer…
The incidence of #livercancer in #HIV\#HCV coinfected patients treated with DAA and LS<14 kPa at the time of SVR is much lower than 1.5 cases/100 person-years, the figure which makes screening cost-effective. Thus, surveillance may be stopped if LS is below to 14kPa at this time.
These data come from the @hepavir @GEHEP_ 011 @riscomunica RIS-HEP 13 study published in advance in Clinical Infectious Diseases Image
Read 3 tweets
1/2 Being a #virologist @DKFZ, I just HAVE to retweet this one. Yes, folks, #viruses do cause #cancer also in humans! Check out my #teaching slide in the next tweet! #HPV #HBV #HCV #EBV #HTLV #CancerResearch #infectiousdiseases #virology
@DKFZ 2/2 Merkel cell #carcinoma is a hideous #disease, but luckily very rare (though almost always associated w/ McPyV on the northern hemisphere). Even much, much more common #cancers are associated with #virus #infections (or #bacteria like H.pylori)! #HPV #HBV #HCV #EBV #HTLV Image
3/2 😅 Sorry, let me add one more remark: of course not ALL the shown #cancer cases are associated with #infections, but a significant fraction of the indicated cancer types are (e.g. #HPV in 99% of #CervicalCancer, aprx. 75% #HBV or #HCV in #livercancer!)
Read 3 tweets
Our lab’s inaugural manuscript is out (PMID: 31424293)!!! First #tweetorial (1/n) #chemtwitter #radonc #academicchatter #newPI #sciencetwitter #livercancer
We have been exploring molecules that can specifically bind to liver cancer to improve upon existing modalities for diagnosis and surveillance. 2/n
So, why liver cancer? About 800,000 people are diagnosed with liver cancer worldwide, with as many people dying from the disease annually. In the U.S., incidence and mortality appear to be increasing. 3/n
Read 13 tweets

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