See Eroom’s Law for how drug development has become exponentially more expensive over the last century: en.wikipedia.org/wiki/Eroom%27s…
Outside of that, we moved very quickly from banning straws & scooters to advocating the breakup or destruction* of the most valuable cos in the US.
These things are never surgical. Startups will also suffer.
* Eg: archive.is/ks1jf
Sophon locking is a technologically superior civ holding back a less advanced civ.
That’s not the case here. Standard luddites just smashed machines. The “human sophons” are more like organized luddites. It’s legalized destruction.