Discover and read the best of Twitter Threads about #systematicreview

Most recents (24)

What causes back pain?🤔
Specifically: how much do nervous system, spine tissue and psychosocial contribute to #backpain?

#systematicreview with multivariate #metaanalysis in European J Pain @EFIC_org

doi.org/10.1002/ejp.18…

Led by @ScottTags 🙏collaborators

Thread
👇 Image
Low #backpain is leading cause of disability worldwide… 90-95% of cases are considered 'non-specific'

Many factors can contribute

Image 👇from doi.org/10.2147/jpr.s1… @chadcookpt

But which ones and how much? Image
Individual meta-analyses + factors associated with back pain
➡️ pain processing doi.org/10.1097/j.pain…
➡️ disc degeneration doi.org/10.3174/ajnr.A…
➡️ muscle atrophy doi.org/10.2522/ptj.20…
➡️ depression / distress doi.org/10.1093/fampra…

But is one more important than other?
Read 13 tweets
New research from @DrAimeeGrant @sara_wyn_jones @KatWilliams123 @AutisticUK @DrSchniff @Prof_AmyBrown, who reviewed Autistic people's experiences of infant feeding (breast- and formula- feeding) including healthcare support

🧵by @DrAimeeGrant

journals.sagepub.com/doi/full/10.11… (1/11)
#Breastfeeding is encouraged because of known health benefits, but it is not easy and many parents experience challenges.

Due to differences in how Autistic people experience pain and bodily sensations, we thought that they may find breastfeeding harder. (2/11)
It's worth mentioning here that the research team was led by an Autistic woman, with two Autistic women who had experience of infant feeding themselves also part of the team. It was funded by the Research Wales Innovation Fund, part of @SwanseaUni (3/11)
Read 11 tweets
A quick #medlibs thread
I've had a few people ask me lately to explain how I think about searches. (Why anyone wants to know that messy process... 😂 ) A lot of my expert searching thoughts and habits are so ingrained, it can be challenging to parse. But here's one example:
Something that I immediately notice about this #SystematicReview is that they don't include a keyword for the term they use to refer to the condition throughout their paper. They have pericarditis and myocarditis, but not myopericarditis.
thelancet.com/journals/lanre…
(screenshot from supplementary material)
Thoughts I have: Why don't they have myopericarditis? If they use truncation, why don't they do that for immuni(z/s)ation term? If they want immunization terms in title and abstract, why not also have Immunization[Mesh]? Image
Read 12 tweets
There are a lot of resources out there that have search hedges /filters beyond published articles. Here's a thread of some I like and have used.
#medlibs #canmedlibs #ukmedlibs #ExpertSearching #SystematicReview
First, the new kid on the block as it were: searchRxiv hosted by @CABI_Research (full disclosure: I gave them feedback during the development)

searchrxiv.org
The ISSG Search Filter Resource from @ISSG_Filters

sites.google.com/a/york.ac.uk/i…
Read 9 tweets
Here's a #SearchAndRescue tip of the day!

Are you putting together a #SystematicReview search?

If you use a subject heading (aka controlled vocabulary, thesaurus term), use the same term as a keyword too.

It seems redundant, but it's not. Let's look at an example:
I looked up the term Guillain-Barre Syndrome in the MeSH database, which is MEDLINE's controlled vocabulary:

ncbi.nlm.nih.gov/mesh/
There's a term for Guillain-Barre Syndrome, here, take a look:

ncbi.nlm.nih.gov/mesh/68020275
Read 10 tweets
Why is it that I spent some three hours over the weekend scrutinizing a #systematicreview in minute detail? I hadn't expected needing to explain my motives but someone forced my hand so here goes. This will be a shorter thread. 1/10
When someone asked Sir Edmund Hillary why he wants to climb Everest, he responded: “Because it’s there”. Similarly, I examine these reviews because I know I can do it well and because I don’t see anyone else doing it out in the open. 2/10
I used to do this for a living. For nine years I worked as Managing Editor of Cochrane Work, which means that not only did I peer referee countless reviews, I led our group’s peer refereeing process. So, I taught our authors and our editors and peer referees. 3/10
Read 10 tweets
This is my open peer review of the systematic review of non-pharma interventions for preventing #COVID19 by @stella_talic et al. that was recently published in @bmj_latest: bmj.com/content/375/bm… Prepare for a marathon of a thread 1/ Image
@stella_talic @bmj_latest I’m using AMSTAR-2 to conduct this assessment. Also, where relevant, I will drop in additional observations based on my 15-year experience working as a Managing Editor in @cochranecollab producing, editing and publishing #systematicreviews. 2/
@stella_talic @bmj_latest @cochranecollab Q1. Did the research Qs and inclusion criteria for the review include the components of PICO? The title nicely lists three outcomes: Covid-19 (getting the disease), SARS-CoV-2 transmission (contracting the virus or passing it on to others) and dying as a result of Covid-19. 3/
Read 54 tweets
🧵THREAD

In honour of the #Hernia2021 congress hosted by the BJS strategic partner @eurohernias, here is a thread of recent hernia-related BJS papers.
European Hernia Society guidelines on management of rectus diastasis #rectusdiastasis #Hernia2021 #Hernia
academic.oup.com/bjs/advance-ar…
Reporting guideline for interventional trials of primary and incisional ventral hernia repair #OpenAccess #Hernia2021 #Hernia #VentralHernia
academic.oup.com/bjs/article/10…
Read 19 tweets
My team from @UNSWMedicine has just released an interesting #systematicreview on RT + body fat in @SportsMedicineJ. Some novel and important findings for ExRx for body comp control. A thread 1/7.

link.springer.com/article/10.100…

@mawewege @bri__clifford @Mattjones0203 @imtiazdesai
2) We found that RT elicits reductions of ~1.4% body fat percentage and 0.55kg body fat mass compared with non-exercise control. Importantly, this is in studies NOT designed for weight loss! We excluded studies with concurrent dietary and aerobic exercise interventions.
3) RT also elicited moderate reductions in visceral fat compared with non-exercise control. This adds more evidence to the broad spectrum of benefit for RT on indices of health.
Read 7 tweets
Our #systematicreview and #metaanalysis on the association of #sepsis with long-term #CVD is out now in @yourICM ! Surviving sepsis was associated with ⬆️#cvMI, #heartfailure, and #stroke over 5+ years. Take-home points below. tinyurl.com/p5n634jy
1. Many studies have examined the risk of #CVD after #sepsis, but variable population and outcome selection has complicated generalizability. We estimated the risk of #cvMI, #heartfailure, #stroke, and composite #CVD after sepsis relative to hospital and population controls.
2. 12,649 citations identified, 27 (25 cohort, 2 case-crossover) studies included. Median of 4,289 (IQR 502–68,125) sepsis survivors and 18,399 (IQR 4,028–83,506) controls per study. We assessed cumulative incidence and relative risk of #CVD from 30 days to longest follow-up.
Read 11 tweets
Is #exercise before or after hip joint replacement better than usual care or minimal treatment?

#Metaanalysis in @JAMANetworkOpen @JAMA_current
dx.doi.org/10.1001/jamane…

Led by Tobias, Jochen and Max from @PhysioMeScience

🙏for #collaboration!

Thread
👇👇👇👇
#osteoarthritis is one of the leading causes of #pain, #disability and healthcare resource usage worldwide.

Total hip replacements (THA below) done per year are expected to grow to ~600k per year by 2030
doi.org/10.2106/jbjs.1…
Some guidelines (both from 2020) recommend exercises with hip replacement

@NICEComms nice.org.uk/guidance/ng157
-pre-op advice only
-post-op inpatient ex ✅, outpatient self-directed exercise only

Dutch doi.org/10.1002/msc.14…
-pre-op ex ✅for specific patients
-post-op ✅
Read 15 tweets
Can #exercise “strengthen” the intervertebral disc?

A brief history of research from 2013 to 2020:

Review: dx.doi.org/10.1007/s40279…
Cross-section: dx.doi.org/10.1038/srep45…
RCT: dx.doi.org/10.1007/s00586…

🙏 collaborators

Thread 👇 👇 👇 👇
#backpain
First, we did a review of the literature (narrative, not a #systematicreview. This was back in my pre-systematic review days!) dx.doi.org/10.1007/s40279… in @SportsMedicineJ

🙏 @DieenJaap, Kirsten Albracht, Prof. Brüggemann, Dr. Vergroesen
It has been well established that exercise and loading can impact IVD height. E.g. doi.org/10.1097/000076… doi.org/10.1249/mss.0b…

So, exercise and movement protocols can at least ‘influence’ the IVD
Read 20 tweets
It's Good Friday.

As a sacrifice to Science, I'm going to criticise every single paper I've ever written, one tweet at a time.

Stay tuned..!

#ImAVeryNaughtyBoy
Paper #1: Holmes & Spence 2004 @xmodal

Criticism: A non-systematic review of selected papers, no assessment of study quality, bias, or effect sizes. The only novel thing in this paper was a long, harsh critique of Iriki et al. (1996)

#SelfCriticism

doi.org/10.1007/s10339…
Paper #2: Skaliora et al. 2004

Criticism: I contributed only one figure (#8) to this paper, but >30 neonatal rats paid the ultimate price for my crappy patch-clamping skills (only 17 cells) as an MSc student. I still feel the guilt.

#SelfCriticism

doi.org/10.1152/jn.004…
Read 60 tweets
🧵🎯Debunking thread:
Σύντομα ξεκινάμε τους εμβολιασμούς κατά #SARSCoV2 & κυκλοφορούν διάφοροι ισχυρισμοί που σκοπό έχουν να δημιουργήσουν αμφιβολίες και σύγχυση

⛔️🎯Εμβόλιο #COVID19: απαντήσεις προς δηλώσεις & ισχυρισμούς που κυκλοφορούν:
1/
🤡Το εμβόλιο δεν είναι ασφαλές🤡
‼️Έως τώρα, εμβόλια έχουν χορηγηθεί σε 100άδες χιλιάδες άτομα σε πολλές χώρες: ΗΠΑ, ΗΒ, Καναδάς, Αυστραλία, χώρες της Ασίας & Αραβικής Χερσονήσου, ενώ αύριο ξεκινούν και στην Ευρώπη.
2/
Δεν έχει παρατηρηθεί ανησυχητική παρενέργεια μετά τη χορήγηση, με εξαίρεση μεμονωμένα περιστατικά σοβαρής αλλεργικής αντίδρασης (συχνότητα ~1/100.000).
Γι’αυτό & η σύσταση είναι να αποφεύγεται το εμβόλιο σε άτομα που έχουν εκδηλώσει σοβαρή αλλεργία (αναφυλακτική αντίδραση)
3/
Read 62 tweets
With 2020 almost over, it's time again to look back at some of the BEST in the #bone field: 🔝20 papers (+extras).

Happy to hear your input! Disclosure: fully subjective ranking!
@ASBMR @AcademyEcts @Osteoporosis_NL @osteoporosisNI @mmse30 @NatalieASims
#1 Atypical Femoral fractures @NEJM (Black DM et al.)
Risk reduces within months of @Bisphosphonate1 discontinuation. Benefit>risk in any group but less so in Asians and women <65yr
nejm.org/doi/10.1056/NE…
-side note- @ECTS_science very useful systematic review and recommendations for managing osteoporosis following AFFs.
ncbi.nlm.nih.gov/pmc/articles/P…

And oral BPs may not only reduce fractures but also cardiovascular events
pubmed.ncbi.nlm.nih.gov/32717068/
@Dr_BoAbrahamsen @prieto_alhambra
Read 24 tweets
#Bevacizumab for #ROP Rx & Neurodevelopment thread

Delighted our #metaanalysis out today in @JPerinatology

Results indicate Neurodevelopment harm associated w/ Avastin Rx

@EBNEO @waseemoddin

nature.com/articles/s4137…

rdcu.be/cbRdK #FOAMneo

1/6
The idea started with a dialogue by a colleague ”We don’t do lasers, they are ancient, we do avastin - simple, easy, less recurrence.”

Me: “there are long term risks - right?”

Colleague: Na, it’s ok, we already accepted & moved 🤨

2/6
I thought it’s good idea to pursue a #Systematicreview as the evidence is sketchy & controversial but what really pushed me to do the review is👇

Avastin can fire the brain for 60 days (#staylong) by suppressing VEGF that is crucial for brain growth

3/6

is.gd/5BE9AN
Read 7 tweets
Good afternoon and good evening…thank you all for joining us for this portion of the 2020 @SOAPHQ virtual annual meeting

What's new in #OBAnes - A comprehensive review of the most relevant articles published in 2019

#MedThread #Tweetorial #Ostheimer #SOAPAM2020
#Halifax would have been amazing - @ruthi_landau and I worked incredibly hard with our amazing management team to bring you an innovative agenda and in many ways we reimagined the way @SOAPHQ delivers an annual meeting #MedThread #Tweetorial #OBAnes #Ostheimer
Most of us have never lived through something like #COVID19 - As we embrace the new normal, remind ourselves of strategies to address our own wellness as physician leaders on the frontline - let's continue to look out for one another! #MedThread #Tweetorial #OBAnes #Ostheimer
Read 106 tweets
In this paper in @NatureEcoEvo we outline 8 major problems that can occur with traditional ways of reviewing the literature, and provide concrete advice on how to avoid them: rdcu.be/b8pp0

This thread outlines our key points! (1/23)
#EvidenceSynthesis #SystematicReview
Traditional ways of reviewing the literature may be susceptible to bias and end up giving us incorrect conclusions.

This is of particular concern when reviews address key policy- and practice- relevant questions. (2/23)
Systematic reviews aim to maximise rigour and minimise susceptibility to bias using rigorous methods.

But despite these methods being available, poor reviews are still published: these could be improved with a few key processes; some not prohibitively costly. (3/23)
Read 23 tweets
In this national longitudinal study of 4570 patients with #heartattack, attendance at #CardiacRehab was associated with a temporal improvement in health related quality of life (#HRQoL) at up to 12 months following hospital discharge. @Heart_BMJ heart.bmj.com/content/early/….
‘Health-related quality of life (#HRQoL) is an important outcome measure following #heartattack’, states @benhurdus first author.
Healthcare professionals (& researchers) have historically focused on objective measures of poor health, such as mortality & life expectancy, but often patients consider improvements to HRQoL equally important to length of life.
Read 32 tweets
Hello #foodstudies20 Conference! I’m pleased to share the highlights of our research: “What do the gender-sensitive guidelines say and advise for the development of agro-value chains? Evidence from a systematic review”. 1/19
This is the result of a joint work with @labuenaempresa, student at @cafnr & @jhonjjhb, colleague of @BiovIntCIAT_esp. Keywords: #ValueChain, #Gender, #Agriculture, #Agribusiness, #SystematicReview. #foodstudies20 2/19
We are a Colombian multidisciplinary team with a common interest on value chains, inclusive business models, gender and agriculture in Latin America. #foodstudies20 3/19
Read 19 tweets
I just have a little Friday favor to ask of all would-be authors hoping to embark on a #SystematicReview.

Before you start, could you please read about #SysRev?

It will help you know what you're getting yourself into.

Thread: Required Reading for #SysRev would-be authors.
There are so many resources out there, like the Cochrane Handbook:

training.cochrane.org/handbook/curre…

This can apply to any SR, need not be a Cochrane SR.
Same for the MECIR Standards:

methods.cochrane.org/methodological…
Read 10 tweets
My tips for conducting a #SystematicReview - a thread.

1. Have a look whether any systematic review or #metaanalysis has been conducted on your topic before. If so, what (gaps) did they uncover? How did they structure their results? How will your review differ?

#phdchat
2. Have a look at the resources available at @PRISMAStatement, including the checklist and flow diagram (prisma-statement.org/PRISMAStatemen…), and use it to guide your processes.
3. Get in touch with the reference #librarian at your institution, or check out the resources available through any #HigherEducation #library website. They'll have valuable insight into search string development and database best practice.

#LibrariesRock
Read 8 tweets
This is becoming my default review template (#SysRev or otherwise) -- lots of links because I want people to have all the resources at their fingertips. You can't say I didn't warn you. #systematicreview #knowbeforeyougo
Well howdy do, it's Friday, let me just give you those links, eh?

PRISMA Statement -- a reporting guideline and checklist for Systematic Reviews and Meta-Analyses:

prisma-statement.org

Yes I said GUIDELINE DON'T WE ALL CHANGE with knowledge
PRISMA-P Extension and Protocol Guidance:

prisma-statement.org/Protocols/Prot…

Checklist for Protocols, which you should probably register on...
Read 7 tweets

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