Heavy metals 1. Lead
Values higher than prescribed @US_FDA➡️ bit.ly/3miSHBM, #Indiabit.ly/3oV794F
Lead in drugs unheard of in developed countries. #India is developing (currently underdeveloped), hence an excuse. Lead limit in paints 90mg/kg. 2/ #MedTwitter
Heavy metals 2. Cadmium
C @US_FDA list beneficial & harmful metals in humans ➡️bit.ly/2LDTEbj
Cadmium prolonged use cause multiple organ toxicity sometime wrongly diagnosed
See bit.ly/37iTVZe
Indian herbs R sources of Cd bit.ly/37ZQTIJ #livertwitter 3/
Here is complete GCMSscan
Lots going on. Industrial solvents,chemical additives. Potential plant toxins
Eg:Eugenol➡️bit.ly/347JkhW
Tropine stimulant in #coronil
Potential useful cmpnds mite B there - V dont know yet.
When unknwn, better 2 stay away
Patient recovered 4/4
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#Ayurveda treatment for alcoholic #liver#cirrhosis - case based protocol, described in a case series of 3 patients.
Once again, forget @NetflixIndia comedy shows, this is where all the fun, comedy and jokes are now.
Caution: This limited series will drop your IQs #MedTwitter 1/
Introduction:
🔅#Ayurveda is a philosophy. Correct. No therapeutic value.
🔅Uncertainty due to uncertainty😳 HUH?
🔅#Ayush guys got 'sanskrit' spelling wrong 😵 whats with that?
🔅Time to combine evidence based medicine with case based medicine. What #herb is the author on? 2/
🌿Alcoholic is not correct. Alcohol related/associated. More compassion toward patient. But what does #Ayurveda know abt compassion right? Need a herb 4 that.
🌿Specifically note the sentence bad mouthing scientific, conventional care. That's hw these #ayush#quacks survive. 3/
1/ Here is something #interesting.
Do U know how long it takes 4 a good liver 2 develop chronic liver disease/cirrhosis? 5-10 yrs. At times more. But here is a patient developing cirrhosis in 6wks. Yes. 6wks. Reason?Excessive #energydrink.Which drink?I cant say, but its a scary 1
2/ Here is the liver biopsy done at the time of liver injury and on follow up at approx. 6 wks. The top panel shows severe fatty liver and liver cell loss, damage/necrosis and the bottom panel, transformation to cirrhosis. Why did this happen?
Ans is a vitamin - Niacin or Vit B3
3/ ➡️Niacin, vitamin B3, is a water soluble, essential B vitamin
➡️Niacin is also found in many herbal mixtures and energy drinks, sometimes in super doses
➡️Well known cause of clinically apparent liver injury when given in high doses
More on that: bit.ly/3mHCPK3
1/ 32 yr male. Routine check in 2017, found 2 have hepatitis C virus (HCV) +ve. That is, anti-HCV +ve meaning exposure to the virus & antibodies in blood. #MedTwitter#livertwitter
2/ To confirm, PCR test 4 RNA has to be done. Which he did. The viral load was 900,000 IU/L. So he goes to a Gastroenterologist, who checks the virus genotype (it was type 2) and puts him on the fantastic direct acting antiviral Sofosbuvir+velpatasvir for 3 months. All good?
No.
3/n He checks Google. Finds cirrhosis, liver cancer etc...gets alarmed and before completing the treatment, checks HCV at 2 months. Finds - anti HCV still +ve.
[note: anti HCV ELISA test STILL +ve]
Feels modern medicine doctor cheated him with expensive drugs.
Enter the dragon.
Here is an example of exactly HOW NOT to design a study and publish.
A grp of #ayurveda vaidyas published:💡Clinical Improvement In #COVID19#patients With Timely Intervention Of Panchagavya: Preliminary Finding
💵International Journal of Pharmacological Research 1/n #MedTwitter
First, choice of #journal. Choose one indexed in valid scientific databases - eg @Scopus, Medline @NCBI, @embase, @EBSCO, @webofscience. International Journal of Pharmacological Research is indexed👇😶
Just bcoz its on Google doesn't mean its quality. #pseudoscience#fake 2/n
There R indexed and impactful journals charging #openaccess fee (eg @JHEP_Reports) if the institute can afford it. Most quality indexed, impactful journals (eg @HEP_Journal) dont have open access fee to publish, but #Subscription fee for persons to read #published study. 3/n