1/ Here is something #interesting.
Do U know how long it takes 4 a good liver 2 develop chronic liver disease/cirrhosis? 5-10 yrs. At times more. But here is a patient developing cirrhosis in 6wks. Yes. 6wks. Reason?Excessive #energydrink.Which drink?I cant say, but its a scary 1
2/ Here is the liver biopsy done at the time of liver injury and on follow up at approx. 6 wks. The top panel shows severe fatty liver and liver cell loss, damage/necrosis and the bottom panel, transformation to cirrhosis. Why did this happen?
Ans is a vitamin - Niacin or Vit B3
3/ ➡️Niacin, vitamin B3, is a water soluble, essential B vitamin
➡️Niacin is also found in many herbal mixtures and energy drinks, sometimes in super doses
➡️Well known cause of clinically apparent liver injury when given in high doses
More on that: bit.ly/3mHCPK3
1/ 32 yr male. Routine check in 2017, found 2 have hepatitis C virus (HCV) +ve. That is, anti-HCV +ve meaning exposure to the virus & antibodies in blood. #MedTwitter#livertwitter
2/ To confirm, PCR test 4 RNA has to be done. Which he did. The viral load was 900,000 IU/L. So he goes to a Gastroenterologist, who checks the virus genotype (it was type 2) and puts him on the fantastic direct acting antiviral Sofosbuvir+velpatasvir for 3 months. All good?
No.
3/n He checks Google. Finds cirrhosis, liver cancer etc...gets alarmed and before completing the treatment, checks HCV at 2 months. Finds - anti HCV still +ve.
[note: anti HCV ELISA test STILL +ve]
Feels modern medicine doctor cheated him with expensive drugs.
Enter the dragon.
Here is an example of exactly HOW NOT to design a study and publish.
A grp of #ayurveda vaidyas published:💡Clinical Improvement In #COVID19#patients With Timely Intervention Of Panchagavya: Preliminary Finding
💵International Journal of Pharmacological Research 1/n #MedTwitter
First, choice of #journal. Choose one indexed in valid scientific databases - eg @Scopus, Medline @NCBI, @embase, @EBSCO, @webofscience. International Journal of Pharmacological Research is indexed👇😶
Just bcoz its on Google doesn't mean its quality. #pseudoscience#fake 2/n
There R indexed and impactful journals charging #openaccess fee (eg @JHEP_Reports) if the institute can afford it. Most quality indexed, impactful journals (eg @HEP_Journal) dont have open access fee to publish, but #Subscription fee for persons to read #published study. 3/n
We give #real#life#patient data supporting our review: such as this example which shows that #Ayurveda#drugs cause severe #chronic#liver#damage that can lead to #cirrhosis in the short term.
The implicated agent here is Holarrhena antidysenterica (Tellichery bark) 3/4
This here, is an imp reason why India never get its right in #healthcare. Extreme fanatics like Ms Deepa is always there, effortlessley moving the topic away from science, spewing poison in general, bcoz she and her likes have nothing constructive to contribute to society. 1/3
They take a science moment and turn it to one which has more hate mongering potential, example religion and bring down the good work contributed by others. Who is this lady to proclaim #Ayurveda as #Hindu. Stupid. It is Indian. I'm a doctor from Kerala, but I'm Indian first. 2/3
You are a fool if you did not know that the biggest and largest Ayurveda based industry and practice especially ancient tradititional family business that operate in India and abroad are mostly Christian and Muslim if you did not know about it. Hypocritical bigot. 3/3