Thread by @drbrowncares

1/ Preventive Cardio-Oncology Tutorial #PrevCardioOnc @PrevCardioOnc #CardioOnc #CardioOncology

“The time has come for cardiovascular disease (CVD) prevention to play a more prominent role in cardio-oncology.”

tinyurl.com/PrevCardioOncT…

2/ “A myriad of novel cardiotoxic chemotherapeutic & immunotherapeutic drugs are continuously being developed in #Oncology, with diverse cardiovascular (CV) effects.”

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#PrevCardioOnc @PrevCardioOnc #CardioOnc #CardioOncology

3/ Chest radiation “can result in accelerated atherosclerosis, pericardial disease, valve disease, conduction abnormalities, & cardiomyopathies.”

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#PrevCardioOnc @PrevCardioOnc #CardioOnc #CardioOncology

4/ “Traditional chemotherapies, endocrine therapies, & targeted or immunotherapies can associate w/ these #CVD toxicities in addition to #myocarditis.”

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#PrevCardioOnc @PrevCardioOnc #CardioOnc #CardioOncology

5/ “Various chemotherapies & targeted/immunologic therapies can also lead to peripheral vascular toxicities, such as systemic hypertension, pulmonary hypertension, thrombosis, stenosis, vasospasm, or vasculitis.”

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#PrevCardioOnc @PrevCardioOnc #CardioOnc

6/ “Prevention can take different forms and can be pursued in different ways, with definition, scope, awareness, partnership, screening, surveillance, and intervention.”

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#PrevCardioOnc @PrevCardioOnc #CardioOnc #CardioOncology

7/ “Thus, as we advocate for moving from a traditionally reactive model to a more proactive model for prevention of cardiovascular toxicities in response to cancer therapies, we are entering the era of Preventive Cardio-Oncology.”

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#cvPrev #CardioOnc

8/ “For 2019, ~2 million new cancer diagnoses & >600,000 new cancer deaths estimated; as cancer incidence continues to ⬆️ for most cancers, cancer mortality continues to ⬇️, leading to millions of cancer survivors each yr.”

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#PrevCardioOnc #CardioOnc

9/ “We can no longer wait to intensify our focus on prevention in cardio-oncology, as the number of survivors of childhood and adult cancers approached 17 million in 2019 and is projected at ~22 million by 2030.”

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#PrevCardioOnc #CardioOnc #cvPrev

10/ “The presence of baseline cardiovascular risk factors raises CVD risk after cancer therapies, but at a higher rate than in the general population due to cardiotoxic effects of cancer therapies.”

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#PrevCardioOnc #CardioOnc #cvPrev #CardioOncology

11/ “1 in 3 👨🏻👩🏽 develop cancer in their lifetime; many will become long-term survivors. ⬆️ facilitating healthy behaviors & surveillance to ⬇️ #CVD, as well as novel methods of identifying those at ⬆️ risk will be needed.”

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#PrevCardioOnc #CardioOnc

#CardioTwitter #Cardiology #HeartHealth @FrontiersIn @ASPCardio @escardio @EuroCardioOnc @ICOSociety @DLenihanICOS_MD @fit_cardio_onc @cardiooncCMB @oncology_cardio @CardioOnc_MR_CT @CardioOncCO @OncoCard_Ganken @MayoClinicCV @AHAMeetings @datsunian @DSadlerMD @OSUCardioOnc