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, 3 tweets, 4 min read
Not to mention that factoring the #microbiome/virome (+ the #pathogens that end up persisting in these communities!) into #ME/CFS 👉 allows “unique #infectious history” to factor into disease progression (w/ #chemical exposures/stress etc facilitaring pathogen persistence)
Also keep in mind pathogens can persist in #latent forms 👉 Eg: here Zika was shown capable of persisting in the #cerebrospinal fluid + lymph nodes of monkeys for months after the #virus had been cleared from peripheral blood and urine: sciencedirect.com/science/articl…
Ok that’s it for now 😅 Thanks for reading!
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Amy Proal
@microbeminded2
Just published: Team uses mNGS + culture-based techniques + negative controls 👉 Identify fungi + bacteria in complex communities in the first pass meconium (stool) of infants☝️Indicates that the neonatal gut microbiome starts to form in the womb: biorxiv.org/content/10.110…
2/2 The organisms they identified colonizing the fetal #intestine prior to birth 👉 were identified in the meconium of both term-born and #preterm newborns☝️And machine learning suggested that #fungal gut communities develop in complexity w/ advancing gestational age at birth.
3/3 Quote from paper 👉 “The demonstration of live #microorganisms in the #newborn gut represents a monumental shift from the sterile #womb hypothesis that dominated perinatal biology for the last century...”
Read 7 tweets
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Amy Proal
@microbeminded2
Wow! 👉 This team found that 84% of patients w/ acute ischemic #stroke had bacterial DNA in their blood clots removed from the #brain ☝️oral #pathogen viridans streptococci (already connected to #endocarditis) was the most common organism identified in the #blood clots
Here is the paper itself which states 👉 “We found DNA of viridans streptococci in most aspired thrombi of patients with acute ischemic #stroke, which suggests that oral bacteria may have a role in the cause of #cerebrovascular disease.”
Also 👉 “Repeated transient bacteremia, caused by poor dental care or bacterial #infections, may trap pathogens in atherosclerotic plaques and promote rupture of the plaques”: ahajournals.org/doi/10.1161/JA…
Read 3 tweets
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Amy Proal
@microbeminded2
Incredibly important hypothesis piece published today 👉 “Proposed here is a theory that #microorganisms from within the #brain and elsewhere in the body contribute to the long-term #neurological deterioration characteristic of traumatic brain injury”: sciencedirect.com/science/articl…
From paper 👉 1. “First, since the normal human #brain is not sterile, but is host to a variety of microorganisms, blows to the #skull may dislodge them from their accustomed local environments, in which they have been living in quiet equilibrium with neighboring #brain cells”
2. “2nd, upon impact commensal #microbes already resident on surfaces of the nose, mouth + eyes, and potentially harmful organisms from the environment, may gain access to the #brain through the distal ends of the olfactory + optic #nerves or even a disrupted blood-brain barrier”
Read 6 tweets

Related threads

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Ifeoluwa Ariyo-Agbaje
@agbajegoriite
Distinguished,

The fact that our dear country do not take responsibility for Nigerian citizens abroad is appalling.

In sane climes, such oversight will not happen; It is a show of dismal and embarrassing image for Nigeria.
Here is the link to a thread I wrote on a similar issue few days ago about whether or not Nigeria still has a NATIONAL INTEREST 🤷🏽‍♂️

Issues vital to national interest are captured under:

1. Primary Interest
2. Secondary Interest; and
3. General Interests.

However, I choose to be explicit on the secondary interest of a nation because it encompasses the crux of this matter.
Read 9 tweets
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RedQueenRedTeam
@RedQRedT
As #espionage & #Eurovision coincide, here's #Albania the 1st finalist in this #history thread.
(Also for my #Australia readers seeking relief from #ausvotes as you start your Saturday, it's impressive you convinced them your continent counts 😎)
Next: #Азербайджан #Евровизија
For #Eurovision #Азербайджан and #Spying studies, here's an article from @warisboring about Azeri #aviation being well-placed to use my #Soviet favourite (Foxbat) to work #intelligence against my #USAF (Blackbird).
Zoom zoom 😎💕

nationalinterest.org/blog/buzz/spyp…
Next up for #Eurovision finalists with an #espionage twist is #Denmark, whose #Spying #Police (PET) scored a serious scoop in turning Colonel Oleg Gordievsky, the #Russian rezident (lead KGB controller), which later inspired actual #JamesBond plot points:
news.bbc.co.uk/2/hi/uk_news/m…
Read 12 tweets
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ѵαɳ∂αɳα🇮🇳
@VandanaJayrajan
#History
In this interview, Dr Ambedkar speaks on M.K Gandhi.(BBC Radio)
He talks of the role of Bose too in the freedom struggle.
Sharing for people to know the history weren't taught.
(Due to video length limit sharing in 2 parts)
P. S : It's there in the public domain.
Part 2.
*we weren't
Read 4 tweets
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Wibke Hott
@WibkeHott
Talking with our local council here in Germany about what (else) we need to do in case of no-deal Brexit, learned that chances are that the German government will have to give out “Aufenthaltsgenehmigungen”, permission to reside. Tentative...
Tentative enquiries from British consulate about the 116000 or so Brits in Germany and their employment status and whatnot to help work out who left I presume (if only they had a citizen register or some sort... 🙄). Also...
Also whether or not you had freedom of movement before Brexit d-day might impact if your permission to reside is time-bound in any way. Long chat about the differences between being a 3rd country citizen having migrated to the EU or a citizen from another EU country. Like...
Read 13 tweets
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Jewhadi™
@JewhadiTM
Democrats Die Again on the Wrong Hill

There seems to be no strategy (there ISN’T) other than Trump rage, and despite going nuclear on a man's life, they just can't win. theamericanconservative.com/articles/democ…
The soiled Brett Kavanaugh confirmation process put Democratic strategy for the 2018 midterms in plain view. The question is: will what hasn’t worked to date do any better for the Dems a month from now?
This week’s FBI investigation was never going to turn up any new information. Apart from liberal Twitter, who are all apparently trauma memory experts (last week they were scholars of perjury law), most normal people have a hard time conjuring details from long ago.
Read 32 tweets
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Ajay
@R_Ajay_
#History/#Art thread – From my recent trip to Madurai/Tirunelveli. On Jain sites (some with a rich history dating back to at least the 3rd cent. BCE), early Pandyan rock-cut cave temples (7th-8th cent. CE) & the amazing Vettuvan koil.

Pic: Mahavira (~8 cent CE), Kizhakuyilkudi
Before I start on the places, the history around all this is fascinating & splits opinion. Is it apt to call the script Tamili/Tamil Brahmi? Did it develop independently in the Tamil country/come with the Jain monks from the north? Were 8,000 Jains actually impaled in Madurai?>
>Were the Saivites overaggressive in promoting their faith? Shall only be happy to discuss on these separately (unless it gets too long/irrational). And I’m not posting every inscription from the places here, despite their importance. Again, shall be happy to discuss them.
Read 41 tweets

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