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26/50 The detected "SV40 promoter with 72bps indel" is a "nuclear localization signal" that means either the #plasmid or one of its expressed proteins can be transported into host cell nuclei,...
27/50 ...where the host DNA is found, creating an open question of whether host DNA interaction will occur and to what effect e.g. integration with human DNA. anandamide.substack.com/p/sequencing-o…
28/50 Potential effects of plasmid #contamination in vivo? Notable, five chemistry professors from German universities have been studying #Pfizer #BionTech's covid vaccine. They addressed some questions to the company. Where does the gray tone come from?
berliner-zeitung.de/gesundheit-oek…
29/50 They got (incomplete) answers via the Berliner Zeitung. They also addressed their questions to the Paul Ehrlich Institute (#PEI) and received no answer from the authority even after two days.
berliner-zeitung.de/politik-gesell…
30/50 Chemist to BioNTech: "We find this answer a bit irritating". They sent #BioNTech another letter to the #PEI with questions that seem obvious to them as chemists. Both letters were not answered increasing their concern further.
berliner-zeitung.de/gesundheit-oek…
31/50 One question was about characteristics of the #vaccine. There are confusing discussions of layman stating that the vaccine look like a clear #liquid.
quora.com/Why-do-vaccine…
32/50 Others describe that "the #vaccine is a white to grayish-white #dispersion." The chemistry professors asked #BioNTech if the gray tone was due to impurities. What’s actually on the official #ingredient list? (FDA Pfizer)
technologyreview.com/2020/12/09/101…
33/50 #BioNTech informed that the substance has no #gray tone, but is "off-white to creamy white". Obviously, the #vaccinating physicians are misinformed in a negligent and irresponsible way...
(Yellow tone against the light (a little blurred) Image
34/50 ...The hue (caused only by #scattering of light, provided no other colored impurities are present) (#Rayleigh scattering) is a parameter correlating with the size of the #lipid #nanoparticles (#LNP)(~60-150 nm)...
sciencedirect.com/science/articl…
35/50 ...and therefore also reflects the state of #dispersion. #BioNTech let the chemists know, via the Berliner Zeitung, that "not all of the #ingredients used are colorless."
36/50 However, the chemistry professors cannot identify any #component in the specified mixture for which they would expect an inherent color.
nature.com/articles/s4200…
37/50 The chemists are asking the company to provide not only suitable #optical #spectra for reliably characterizing the colorfulness and #scattering strength of the #dispersion,...
38/50 ...but also the methods for determining the identity and amount of #impurity so that they can assess the cause of the different color impressions.
39/50 Irrespective of that, the #LNP component of the #gene #therapies has the potential to encapsulate the #dsDNA #contamination just like it is intended to encapsulate the mRNA payload...
40/50 ...#LNPs have no targeting and #transfect everything they come into contact with.
41/50 If this happens, #dsDNA contamination would be delivered in vivo in the same way as the #mRNA #payload i.e. hidden from the immune system, throughout the entire body, into cells (#biodistribution)
42/50 Cells can replicate and interact at the nuclear level i.e. with access to the human #genome. In vitro study revealed that BNT162b2 mRNA is reverse transcribed intracell. into DNA in as fast as 6 h upon BNT162b2 exposure (LINE-1 reverse transcript.)
mdpi.com/1467-3045/44/3…
43/50 That experiment does not necessarily mean it will happen in vivo in other non-cancer human cells, but that research warrants further studies! In this context, however, McKernan points out that when #dsDNA #contamination is present in sufficiently large quantity,...
44/50 ...it can potentially integrate with human #DNA by sheer force of contamination i.e. without the LINE-1 RT process being employed (McKernan).
45/50 Manufacturer animal #biodistribution studies show that the #LNPs can get literally anywhere in the body, thereby delivering their payload (mRNA or #dsDNA) to cells of all tissue types, incl. into the intestine, where gut #microbiome bacteria reside.
ncbi.nlm.nih.gov/pmc/articles/P…
47/50 In McKernan's view, it is a result of the manufacturing process that employ engineered E. coli #bacteria in which the #dsDNA #plasmids are grown.
anandamide.substack.com/p/pfizer-and-m…
48/50 The #plasmids are a DNA template from which the #mRNA active ingredients of the #Covid #gene #therapies are derived. Thus, the quality of the plasmids are fundamental to the quality of the mRNA #payload (paraphrasing MHRA).
49/50 The production process should extract the #plasmids from the E. #Coli #bacteria, derive the #mRNA payload and then purify the mRNA.
50/50 Conclusion: Urgent further experimental #investigation into the content of production #vials of all #Covid gene #therapies to verify (or to falify?) McKernan et al's findings. McKernan seeks precisely greater involvement and active #peer #Review of his work.
51 #McKernan has made fully available, for low cost, all the means to independently verify his work. Credit @Kevin_McKernan
For further information and access to full sourcing of all of the issues described herein, please see the following articles:
veryslowthinking.substack.com/p/mckernan-dna…
54 Lipid #Nanoparticle (#LNP) composition drives mRNA delivery to the #placenta
biorxiv.org/content/10.110…

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More from @MusiciScience

Apr 2
1/50 #Science is an ongoing process that serves to investigate phenomena, gain new insights or "correct prior knowledge" and this only works in #discourse. This includes diversity of #Opinion, #tolerance and a broad debate space. This is a large thread.
2/50 "#trust the science" is in my view the most #antiscience statement ever. #Questioning science is how you do #Science. This thread gives some examples and further questions.
scientificamerican.com/article/why-do…
3/50 What about good ##scientific #Practice? I found a glaring example here (of all things, in what I consider to be a rush to #vaccine #approval). #blotgate
trialsitenews.com/a/startling-ev…
Read 28 tweets
Mar 13
Making #viruses more dangerous. #Gain-of-function research by #Pfizer: It is creepy to magnify the dangerousness of #germs. For me, it is a form of madness. This is a thread.
@Markus_Krall, @SchellenbergerMD @SimeonPreuss @aya_velazquez @punctpreradovic @SHomburg
1/20
The U.S. continues to fund this type of research, namely in various places outside the U.S. (#Wuhan, #Ukraine, ...), and according to various sources, sometimes even in direct collaboration with #Pfizer.
clubderklarenworte.de/wie-macht-man-…
See references in this article. 2/20
It is just as creepy to increase the dangerousness of conflicts in order to better sell one's expensive #armaments to the man/woman. For me, this is just another form of the same greed-driven madness.
bpb.de/themen/medien-…
3/20
Read 21 tweets
Mar 11
Never forget. Especially (small) children and young people as well as older citizens have considerably suffered from the lockdowns and other measures at that time. In real life (at that time), I often observed people and kids wearing masks fitting badly, being too big etc... 1/7
...and thus can hardly filter because of leakages. Therefore, it is extremely important that masks should have different sizes. Shoes also have various sizes and shapes. 2/7
When singing and speaking, the mask also loses its filtering performance after a certain time due to increased humidity. In addition, the former loses function under humid conditions, while the latter operates with a significant air-pressure drop... 3/6
Read 11 tweets
Feb 12
Frankreich hat 56 AKWs (!) mit ca. 61 GW installierter Nennleistung = ca. 69% Anteil Kernenergie an der Stromerzeugung (Stand Febr. 2023). 1/ 17
world-nuclear.org/country/defaul…
Zum Vergleich Deutschland hat nur (noch) 3 AKWs mit ca. 4 GW installierter Nennleistung (entspricht ca. 3,7 GW netto) = ca. 12% Anteil Kernenergie an der Stromerzeugung (Stand Febr. 2023). 2/17
world-nuclear.org/country/defaul…
Wieviel Windkraftanlagen (WKA) müssen gebaut werden, um die 3 AKWs, die wir noch haben zu ersetzen? Wir ersetzen hierbei CO2 frei durch CO2 frei, das heißt da ändert sich nichts. 3/17
Read 17 tweets
Dec 13, 2022
My feeling is that many people in times of crisis (#corona, #EnergyCrisis, #inflation) do not perceive or hardly perceive (correctly) some natural phenomena at night, such as the starry #sky.
1/9
This can sometimes be seen beautifully even in big cities like #Berlin (See videos by @MusiciScience on various platforms).

2/9
In addition, there are also certain #acoustic #phenomena that probably few people think about. For example, I wondered why I sometimes wake up at night. An #audio spectrum analysis may reveal the cause. Take a look at the video in the last tweet in this thread.
3/9
Read 9 tweets
Nov 20, 2022
The interior of a single virus particle  contains a dense assembly of #ribonucleoproteins (RNPs) that package the genome to form the #nucleocapsid (protein shell of a virus). Notable, it has a cylindrical shape that matches the particle geometry. 1/10
nature.com/articles/s4200…
However, many peope have not understood that these viruses do not #spread exponentially, but in waves (fairy tale of #exponential #growth). 2/10
In this regard, Farr's Law should be mentioned (William #Farr on patterns of #epidemic events), which was banned from the German #wikipedia at the time, but could still be read in the English wikipedia. In the meantime it has marginally reappeared. 3/10
oxfordbrazilebm.com/index.php/covi…
Read 10 tweets

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