Discover and read the best of Twitter Threads about #ncov2019

Most recents (24)

@Ayjchan @NoWackyScience @rowanjacobsen @BostonMagazine @flavinkins @Arkancideisreal @shingheizhan Not me

IMHO every piece of circumstantial evidence - every single one - strengthens the hypothesis

& by now preponderance of direct evidence favors lab too

Will come: whisteblower w docs from Wuhan labs Image
@Ayjchan @NoWackyScience @rowanjacobsen @BostonMagazine @flavinkins @Arkancideisreal @shingheizhan @loosewomen @zerohedge #ncov2019 "Unusual Features of the #SARSCoV2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route"
by whistleblower @LiMengYAN119 and Kang, Shu & Guan, Jie & Hu, Shanchan

zenodo.org/record/4028830… Image
Read 14 tweets
@rajfortyseven @WHO This problem has not been solved and has gotten worse since 2002 china.org.cn/english/enviro…
@rajfortyseven by @EpochTimes Severe structural problems Three Gorges Dam. Build 1994-2006. No final inspection & acceptance report

via @chigrl
Hydrologist Weiluo in June: Dam could collapse at any moment.

44+ million evacuated so far
Red (highest) weather alert today
asia.nikkei.com/Economy/Natura…
Read 11 tweets
@yaobviously #ncov2019 "observations confirm that there is a substantial probability that normal speaking causes airborne virus transmission in confined environments."
> 0.01% : probability 1-μm (3-μm) droplet nucleus contains a virion
medicalxpress.com/news/2020-05-v… &
paper pnas.org/content/117/22… Image
Read 3 tweets
Ingredients for a successful approach in managing pandemic:
1. Value Field experience
2. Utilise knowledge and skills
3. Abundant Precautions in communication
4. Unbiased analysis
5. Use Common sense

#2019nCoV #leadership #coronavirusindia
1ofN
6. Ethics should be as integral as epidemiological principles in the strategy

7. Ensuring Equity is the goal, not an accessory. Think of vulnerable before thinking of self preservation

2ofN #COVID__19 #pandemic #MigrantWorkers
8. Be open. Do not close doors to Ideas
People
Hypotheses
Alternatives

3ofN #2019nCoV #TheWHO #Asymptomatic
Read 6 tweets
#CelebremosLasVictorias
#celebratethevictories #DefeatTheVirus
🔆Crónica de una victoria “atípica”

Ella es mi nonna, se las presento. La mujer más increíble que conozco.
Le dieron su alta médica después de derrotar a este terrible virus.
Tiene 99 años y está historia #Covid
Todo empezó con una visita al médico para tratar un tumor de piel en la nariz.
Fue un miércoles, fuimos con todas las precauciones posibles.Esto fue por allá del 18 de marzo
4 días después de la nada,fiebre ligera y tos.Pensamos que podía ser una infección urinaria ¿pero la tos?
⛔️Al día siguiente, el lunes 23 mucha tos y mucha fiebre. La llevamos con mucha angustia a consulta con un excelente Dr. Neumologo
Los rayos x mostraban una neumonía complicada, con infiltraciones bien definidas.
TODOS los síntomas clínicos coinciden con #SARSCoV2 #Covid19
Read 25 tweets
The role of police in public health is very limited and can be counter-productive. Most successful programs in India (smallpox & polio eradication) and almost zero involvement of the police. It is time #publichealth workforce, methods and strategies are given focus than force.
With force, people may conceal, fear or stigmatize. Instead, empowering people with information by interpersonal communication from health workers promotes trust; very important in ensuring long term success. Community participation and solidarity has helped Kerala's success.
Using public health methods and resources takes longer and involves people who know how to prevent the spread of diseases; you get the desired results in the long run. Not same with quick, short term fixes such as policing & border control strategies (between wards, districts).
Read 4 tweets
Mega Dump
HIV/AIDS+CF/ME+SARS+COVID19 Research

Manufacturing a crisis

ICU
5:5 LOUD & CLEAR
#UseDiscernment #ThinkForYourself
#TheGreatAwakeningWorldwide
Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag
*WITHDRAWN
biorxiv.org/content/10.110…
Don’t believe the conspiracy theories you hear about coronavirus and HIV. Especially if you work for the New York Times

massivesci.com/notes/wuhan-co…
Read 172 tweets
1. I received this from a person incarcerated in HMP Erlestoke. This is one of many accounts of an escalating situation. I need help sharing these accounts and for people to take action. @WarrCriminology @OwenJones84 @psn_ldn @novaramedia @netpol @zoeconway1 @AmnestyUK
2. ‘They’ve got prison officers going into cells spinning (searching), going into people’s self distancing space, touching all their sides and surfaces with the same gloves, or bare hands after they’ve just spun the first man’s cell on the same wing, or previous wings.’
3. ‘So that person’s gloves are contaminating from cell to cells, from wing to wing, and on top of that, in the hope of what? A phone? So you’re going to risk someone’s health/life for a phone?’
Read 19 tweets
@lumidek FWIW
IMHO overall mortality is much lower (certain lower than 8-20% or 1% even)

Chinese mortality much higher bc ACE2 exacerbated by wide-spread smoking (air quality in general) & peculiar ISG property wrt ACE2 of #nCoV2019
@lumidek Fine particulates matter (PM2.5) emitted from coal-fired power plant sciencedirect.com/science/articl…
China coal capacity zawya.com/mena/en/busine…
Read 7 tweets
#COVID19 for the Nephrologist- Real life experience from Italy @caioqualunque Webinar now available on the ISN Academy
@caioqualunque Thank you for sharing your experience with the ISN community. On the panel ISN President @vjha126 Moderator @arvindcanchi. ISN education highlights by @gag_aggarwal
@caioqualunque STORY OF THE EPIDEMIC-Feb14 38yr old Italian starts with symptoms after being asymptomatic for weeks->Feb 20 only 3cases->fast forward to 2 weeks later the country is in lockdown #COVID #COVID2019italia #COVID2019india #COVID2019 #nCoV2019 #Covid_19
Read 39 tweets
1/n
Really pleased to hear that #nCoV2019 testing will be ramped up in the UK - it wont be easy but it will be worth it.
Heard some concerns about how well a nose/throat swab will work.
2/n
But I think that those concerns can be allayed by thinking about where most of the viral replcaition is taking place in different presentations/stages of the disease.
3/n
In a hospital setting (where initial concerns were raised about the sensitivity of the testing and sampling), the admissions will have pneumonia so most replication will likely be happening deep in the lungs - a throat swab might not be great
Read 7 tweets
#ncov19 ACE2 interferon stimulated gene in human upper airway epithelial cells via @halvorz
> interferon used in treatment of viral infections as adjunctive therapy
> found ACE2+TMPRSS2+ at low frequencies in upper airway, lower lungs, digestive system
threadreaderapp.com/thread/1240043…
#LANL D614G isolate / strain #ncov2019

> world-wide data story well told SME
@39Magilla threadreaderapp.com/thread/1260617…
> Pro: R++ plausible SME @trvrb
threadreaderapp.com/thread/1257825…
> Contra: founder effect [noise error-prone RNA synthesis] virology.ws/2020/05/07/the…
IMHO:
> weakens-- causative link public health interventions "correlation not causation" (no magic formula in DE, 'simply lucky' early infections from milder strain)
> 29k tRNA nucleotides, <30 nucleotide mutations (yet 1 improved binding behavior)
> janitor likely right again ImageImageImageImage
Read 4 tweets
A thread on #COVID19

Just a question on the Coronavirus: How can we know the accurate death rate if until about a week ago there was no accurate test (or ANY tests)? Also, there is still no accurate means of determining the number of people ACTUALLY infected...
1)
...as virologists and health experts tell us that most of the people infected with #nCoV2019 show few or no symptoms whatsoever.

Doesn't this mean that the 'death rate' percentage cited by a breathless media is based on a woefully incomplete dataset, and...

2)
...the ACTUAL death rate would therefore be MUCH lower than the figures being touted?

Also, if the death rate WAS higher than SARS, MERS, and H1N1- wouldn't there already be a massive amount of deaths in the US? So far in the US, the number of deaths is <100.

3)
Read 10 tweets
1/ UK response to #covid19. Some people are saying we must follow the expert advice of the gov. and trust in their judgement. And I agree we should be trusting expert advice right now. But what we don't know is what's being said behind closed doors.
2/ We don't know if the gov. advisors are tearing their hair out, battling with Boris and Cummings to take it more seriously. None of know what is actually being said.
3/ They keep saying 'the scientific evidence informs our decisions,' and yet plenty of scientists and experts outside of the gov. are saying the response is weak.
Read 11 tweets
as long as corona virus doesn't cross throat it isn't serious

once it infects lungs, most (except children, pregnant women) develop cytokine storm immune reaction

Old, sick people will suffer. Need lots of Oxygen (ventilators & emergency care etc)

Hope govt paying oxygen bills
#CancelEverythingNow
#FlattenTheCurve

This is doctors in America trying to learn from experience of Italy

#CancelEverythingNow
#FlattenTheCurve

This will impact old people, sick/immune compromised people & vulnerable people without access to medical care

Only preventive option is SOCIAL DISTANCING

Read 36 tweets
The Novel Coronavirus 2019 Epidemic and Kidneys ca. 2020

“Postulated” mechanisms:
👉🏼 Sepsis leading to cytokine storm syndrome
👉🏼 Direct cellular injury due to the virus

#nCoV19 #nCoV2019 #COVID2019 #COVID19 #CoronaKidney
👉🏼 kidney-international.org/article/S0085-… ImageImage
Coronavirus Disease 2019 (COVID-19): FAQs for Transplant Recipients from @AST_info
#nCoV19 #COVID19 #COVID2019 #CoronaKidney
📌 Last updated March 9, 2020
👉🏼 myast.org/sites/default/… ImageImageImageImage
COVID-19 Information for Providers of Dialysis Services from @ASNKidney
#nCoV19 #COVID19 #COVID2019 #CoronaKidney
👉🏼 REGISTRATION register.gotowebinar.com/register/76906… ImageImage
Read 150 tweets
THREAD

Over 60 million Italian citizens under lockdown as #Coronavirus incidences surge. Over 9000 confirmed cases in Italy & rising.

The unfortunate consequence are the associated ethical concerns regarding resource allocation.

More Below

#COVID19 #nCoV2019 #2019nCoV

1/5
Incessant rising in cases warrants the question: are hospitals prepared for the associated influx of patients?

Further admissions require beds, PPE, ventilators, staff etc. What happens when resources run out, ventilators are all in use, or there aren’t enough staff?

2/5
Ultimately, scarcity of medical resources may pressure healthcare practitioners to decide who receives care. This is NOT a question anyone should ever have to answer.

Resources should never be the limiting factor of care

3/5
Read 6 tweets
1/ Notes from the front lines:
#Sharing from another physician:

From an ID conference in California

3/8/2020

Infectious Disease Association of California (IDAC) Northern California Winter Symposium on Saturday 3/7.
2/

In attendance were physicians from Santa Clara, San Francisco & Orange Counties who had all seen and cared for COVID-19 patients, both returning travelers and community-acquired cases. Also present was the Chief of ID for Providence, who has 2 affected Seattle hospitals.
3/

Erin Epson, CDPH director of Hospital Acquired Infections, was also there to give updates on how CDPH and CDC are handling exposed health care workers, among other things. Below are some of the key take-aways from their experiences.
Read 22 tweets
I wanted to preface future bits of science with some personal perspective. I've been using Twitter as "science blog" for years and was posting observations on #nCoV2019 from Jan 11 (). 1/5
"Science Twitter" is a wonderful place and there has been fantastic dialog between scientists since January (shoutout to @arambaut, @cmyeaton, @K_G_Andersen, @richardneher, @MarionKoopmans, @RELenski, @firefoxx66, @AdamJKucharski, @SRileyIDD, @C_Althaus, @rozeggo). 2/5
My initial dialog with scientists has spiraled somewhat out of control and I now find myself with ~100k followers and rather than a dialog it's become more about reporting / outreach. This is intimidating but I'll do my best to with it. 3/5
Read 5 tweets
1/n
One if the reasons we should all do our bit is tgat here in the UK, according to this study:
ncbi.nlm.nih.gov/pubmed/30857602
There is 1 critical care (ICU/IDU) bed per 10,000 people.
2/n
There are approximately 65M people living in the UK. None of whom will have immunity to #nCoV2019 (except the tiny fraction that have already been infected).
3/n
The estimates for the number of people that could be infected in the first wave of the epidemic is impossible to predict, but let’s take a conservative estimate of 30%. Thats 65M x 0.3 = 19.5M. If it was lower, say 10% then that would be 6.5M
Read 5 tweets
There are several pharmaceutical and Biotech companies working round the clock to develop #covid19 vaccine ... I will shed some light on what’s in pipeline on this thread ... 👇
1- #Favilavir, the first approved coronavirus drug in #China- The National Medical Products Administration of China has approved the use of Favilavir, an anti-viral drug, as a treatment for #coronavirus.
The drug has reportedly shown efficacy in treating the disease with minimal side effects in a clinical trial involving 70 patients. The clinical trial is being conducted in #Shenzhen, Guangdong province. According to Clinicla Trials Arena.
Read 19 tweets
Infographic and FAQ sheet with Information for Screening and Management of COVID-19 in the Outpatient Dialysis Facility from @ASNKidney
#nCoV2019 #COVID19 #COVID2019 #DialysisDirector
👉🏼 Infographic asn-online.org/g/blast/files/…
👉🏼 FAQ asn-online.org/g/blast/files/… ImageImageImageImage
The Novel Coronavirus 2019 Epidemic and Kidneys ca. 2020 from @Kidney_Int @vjha126

“Postulated” mechanisms:
👉🏼 Sepsis leading to cytokine storm syndrome
👉🏼 Direct cellular injury due to the virus

#nCoV19 #nCoV2019 #COVID2019 #COVID19 #Nephpearls
👉🏼 kidney-international.org/article/S0085-… ImageImage
Read 4 tweets
Corona Virus Update Thread:

#coronavirus #covid19

China 76,290
Others 634
South Korea 346
Japan 105
Singapore 85
Hong Kong 68
Thailand 35
US 35
Taiwan 26
Malaysia 22
Italy 20
Australia 19
Iran 18
Germany 16
Vietnam 16
France 12
Macau 10

gisanddata.maps.arcgis.com/apps/opsdashbo…
2/ China has extended its quarantine to 760 million citizens (10% of humanity) as the #coronavirus continues to spread. #covid19

nytimes.com/2020/02/15/bus…
3/ Only three US states can currently test for the #coronavirus.

#covid19

cnbc.com/2020/02/21/onl…
Read 25 tweets

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