1/5 "The analysis revealed that older, #cognitively #healthy #brains showed similar amounts of #dissolvable, #non-#fibrillar #amyloid #protein as #brains of #Alzheimer’s #patients."

#aβ #Aβ #fibrils

gero.usc.edu/2023/01/05/new…
2/5 "But, as the researchers expected, the brains of #Alzheimer’s patients had higher amounts of #insoluble #Aβ #fibrils, the form of #amyloid #protein that aggregates to form the telltale “#plaques” seen in the #disease,..."
3/5 "... higher levels of #fibrillary #amyloid appear to be a better indicator of #poorer #brain #health."
4/5 "Rather than #Alzheimer’s simply involving increased production of #Aβ #protein, the more important issue may be a #reduced #ability to effectively clear the #protein and stave off the creation of #plaque-contributing #fibrillary #amyloid,..."
5/5 "These findings further support the use of #aggregated, or #fibrillary, #amyloid as a #biomarker for #Alzheimer’s #treatments,..."

alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with TaNaisha NOT MILD Lee

TaNaisha NOT MILD Lee Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @TaNaishaJ

Jan 10
2/5 "#Uncanny #similarities with #amyloid-#disease associated #blood #coagulation and #fibrinolytic #disturbances together with #neurologic and #cardiac problems led us to investigate the #amyloidogenicity of the #SARSCoV2 #spike #protein (#S-protein)."
3/5 "#Amyloid #fibril #assays of peptide library mixtures and theoretical predictions identified seven #amyloidogenic #sequences within the S-protein."
Read 5 tweets
Jan 10
1/5 As many of you here watch family, friends, associates and colleagues living their best lives out there, as #COVID19 surges, please know that many ARE NOT okay.

"Psychoanalyst Judith Alpert theorizes that our culture is terrified of death, illness, and vulnerability."
2/5 "Thus, “[t]hose who have contact with the #chronically #ill . . . do not want to be #reminded of #vulnerability and #ultimate #demise. In turn, the demand placed on the chronically ill is to #control, #hide, and #overcome the #chronic #illness.” (Alpert, 2012)."
3/5 Many of those who appear to be living their best lives are faking wellness to fit in.
psychologytoday.com/us/blog/chroni…
Read 5 tweets
Jan 10
1/2 "Here, we demonstrate an increased survival of infected #honey #bee #larvae after their #queen was #vaccinated, compared to offspring of #control #queens (#placebo vaccinated)."

frontiersin.org/articles/10.33…
2/2 "These results indicate that #trans-#generational #immune #priming (#TGIP) in insects can be used to majorly enhance #colony #health, protect #commercial #pollinators from #deadly #diseases, and reduce high #financial and #material losses to #beekeepers"
1/2 "The idea came to be known as the “#butterfly #effect” after Lorenz suggested that the flap of a butterfly's wings might ultimately cause a tornado."

technologyreview.com/2011/02/22/196…
Read 4 tweets
Jan 10
1/5 "The 2022 WMO/#UNEP #Ozone Assessment contains the most up-to-date understanding of ozone #depletion, reflecting the thinking of hundreds of international scientific experts who contribute to its preparation and review."

#NOAA

csl.noaa.gov/assessments/oz…
2/5 Does anyone with expertise in this area know why charged particles in plasma from #solar #flares, #coronal #mass ejections (#CMEs) and even #localized #thermonuclear #bursts, i.e. #micronovae, were not considered in this report?
3/5 The recommended terms of reference of the 2022 Assessment for the Scientific Assessment Panel (SAP) was supposed to include assessment of information and research related to
solar radiation management and its potential effect on
the stratospheric ozone layer.
Read 7 tweets
Jan 9
1/4 "Researchers from the University of Colorado Boulder found in a 2019 study that the average house is prone to “#indoor #air quality levels on par with a polluted major city.”"

eurekalert.org/news-releases/…
2/4 "Preliminary results from the study show that #air #quality levels were so poor at the end of the study, the researchers had to recalibrate their #sensitive instruments almost immediately."

#indoor #air #quality
3/4 "So, breathe easy by investing in a high quality #air #purifier. If you’re looking for the best air purifier on the market, we did the research for you by scanning 12 #expert #reviews."
Read 4 tweets
Jan 9
1/6 Interesting work from Dr. William Encinosa and colleagues, with #Black #children disproportionately affected...

#complications #adverse #drug #events #costs #disparities #multisystem #inflammatory
#syndrome #MISC #children #COVID19 #LongCovidKids

jamanetwork.com/journals/jaman…
2/6 "Did outcomes vary by the number of organ systems affected in #multisystem #inflammatory #syndrome in #children (MIS-C) in 2021?"
3/6 "In this cross-sectional study of 4107 #MISC #hospitalizations, as the number of #organ #systems affected increased from 2 to 6 or more, mortality increased from 1% to 6%, length of stay doubled from 4 to 8 days,..."
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(