Discover and read the best of Twitter Threads about #paracetamol

Most recents (14)

[THREAD] L'assurance maladie publie quelques rares données open source sur les médicaments remboursés par la Sécu, dont la base Open Medic (…).

Jusqu'à l'année 2020 INCLUSE, le nombre de boites de médicaments prescrits était en baisse et le coût en hausse : Image
Dans la base #OpenMedic, les médicaments sont référencés avec le code CIP (Club Inter Pharmaceutique). Mais dans certains cas, comme le "vaccin COVID" de #Pfizer, par exemple, AUCUN remboursement n'est référencé par le code CIP 3400928099747 :… Image
Pour les "vaccins #COVID", le code CIP n'est pas utilisé pour la facturation. Les injecteurs ont dû utiliser le code acte "KGP".

La base OpenMedic ne permet donc pas de compter les boites de "vaccins COVID" et leur remboursement normalement.… Image
Read 28 tweets
Giving #Paracetamol in cases of mild #Viral #fever may be harmful
1. It is a common practice to give paracetamol (acetaminophen) to children or adults suffering from viral fever. Research evidence shows that we may be causing more harm than good by this practice.
2. Fever is not a disease; it is a symptom of viral infection. Paracetamol can not kill the virus.
Acute infections, including those due to Corona virus and other viruses, often stimulate a febrile response.
3. A mild fever appears to improve #outcome; as it diminishes viral replication by several mechanisms, including virion entry into host cells and genome transcription, and improving host defense mechanisms against the pathogen.
Read 6 tweets
#Prayagraj व देश में #dengue के बढ़ते केस व #platelets के लिए मचे हाहाकार के कारण मैं ये पोस्ट पुनः लिख रहा हूँ!

घर पर बन सकने वाला ये #Ayurveda #काढ़ा #प्लेट्लेट्स संख्या कम होने से सफलतापूर्वक रोकता है, ऐसा मेरा 12 वर्षों का अनुभव है!

कृपया शेयर कर लोगों की सहायता करें!

हर साल ये काढ़ा मैं हज़ारों मरीज़ों को देता रहा हूँ, लेकिन फिर भी असंख्य मरीज़ों को ये काढ़ा मैं नहीं दे पाता हूँ,
इसलिए इस काढ़े को #घर_पर_बनाने_का_तरीक़ा मैं फिर से शेयर कर रहा हूँ, ताकि आप इसे घर पर भी भविष्य की ज़रूरत के लिए बना कर रख सकें!


1 लीटर काढ़ा बनाने में मात्र लगभग ₹3000/ का खर्च आता है (अगर जड़ी बूटियाँ ठीक मिल जाएँ तो), और इतना काढ़ा #Dengue के 2 रोगियों के लिए पर्याप्त है!

निम्नलिखित सूखी हुयी जड़ी-बूटियों को बराबर मात्रा में लीजिएः

1. अतिविषा
2. द्रोणपुष्पी
3. वासा
4. हरीतकी..
Read 16 tweets
1) A brief review of paracetamol aka PCM

Synthesized by HN Morse at John Hopkins at 1977 --> a derivative of acetanilide and phenacetin.

It has become a common household drug since the 1980s as phenacetin use dropped --> concerns of analgesic nephropathy.
2) It is best known as acetaminophen aka Tylenol in the Western hemisphere.

PCM provides good antipyresis and analgesia --> but anti inflammatory action is minimal.
3) PCM is basically an NSAID that blocks COX1 and COX2 enzymes --> at the peroxide site (distinct among NSAID).

But inflammation raises local peroxide levels --> counters PCM action.

So PCM is a great antipyretic and analgesic but poor anti inflammatory.
Read 10 tweets
#valiantorganics Update :
1. OA capacity expanded to 4800 MT
2. ONA (Raw material for OA) capacity increased to 7200 MT. It will increase the margins. (New Product)
3. #PAP #paraaminphenol Production started. 200 MT in Q1 and expected to be 2300 MT in FY22. Total capacity 9000MT
4. Increased the stake in bharat chemicals from dhanvallabh venture LLP ( from 40 to 50%)
5. #bharatchemicals capacity of #paracetamol increased to 9000 MT
6. Raw material price increased in Q1, which will be passed on in Q2. #OA,#ONA,#PA,#PNA,#PAP will started contributing
7. New capex for #apis (chemicals for APIs). Mostly for apis manufactured by #aartiindustries and #aartidrugs
Intermediates will be manufactured for following APIs :
1. Ranolazine
2. Benazeprill
3. Elagolix
4. Pranlucast
5. Moxifloxacin
6. Ramipril
7. Montelukast
8. Quinapril
Read 4 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action.…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
Hablemos de Alacramyn y Alacranismo #Toxicologia #Urgencias
La producción de sueros hiperinmu-
nes para venenos de ofidios, en el Instituto Butantan de São Paulo, motivó a Carlos de la Peña
e Isauro Venzor, en la Ciudad de Durango (México) a ini-
ciar en 1926 estudios para elaborar un suero hiperinmune
contra el piquete del alacrán.
En específico del alacrán Centruroides sufusus sufusus,
con este fin sometieron a un caballo a la administración de
veneno a dosis creciente (en lapsos de tres a cinco días)
por poco más de tres meses: empezaron con el veneno
contenido en 0.6 de telsón
Read 17 tweets
Why do bartenders have the most experience dealing with the differences in how women and men metabolize a drug?

Because alcohol.

A short thread on how medicine doesn't consider drug metabolism differences between the biological sexes.

1/5 Image
We used to think that differences in alcohol tolerance between M + F was only due to any differences in weight/fat.

But that's not the whole story.

Even when sexes are matched for weight, there is a marked discrepancy in which sex metabolizes alcohol faster, M>F.

2/5 Image
Women don't have the same level of activity of alcohol dehydrogenase, an enzyme which helps break down alcohol in the body.

And other enzymes that break down prescription drugs may also be less active in women, making them more likely to experience adverse side effects. Image
Read 7 tweets
Yesterday I wanted to buy a #OnePlus 8Pro but I stopped because it's made in #China. So I changed my opinion and searched for #iPhone, sadly 80% of iPhones are made in China☹️ Finally I decided to open #Flipkart to search for other mobiles but flipkart is funded by Chinese 🤘👇
I was extremely disappointed and thought of eating some delicious food 🍴🍕🍔 for that I opened #Zomato and #Swiggy irony is that both are funded by Chinese firms. Finally I decided to order some snacks from #Bigbasket, this is also funded by china. 😭🥵👇
I was vexed and wanted to go to restaurant and eat 🍝 . To go there, I tried booking #Ola and cancelled because China funded Ola too. I wanted to compromise for food but Ola driver was accepting ride only if I pay through #Paytm but again China has made investment in Paytm. 👇
Read 5 tweets
22/06 > Selon une expérience de laboratoire, Il est possible de tirer de l'énergie d'un #TrouNoir via @IFLScience #LaMethSci Image
[L’étude à découvrir] 22/06 > Amplification des ondes d'un corps en rotation via @NaturePhysics #LaMethSci
22/06 > Les vaccins vivants atténués pourraient protéger contre la plupart des symptômes graves du #CoVid19 via @ScienceNews #LaMethSci Image
Read 6 tweets
.@MEAIndia: We have seen some attempts by sections of the media to create unnecessary controversy over the issue of #COVID19 related drugs and pharmaceuticals. Our first obligation is to ensure that there are adequate stocks of medicines for the requirement of our own people
.@MEAIndia: In order to ensure this, some temporary steps were taken to restrict exports of a number of pharmaceutical products. In the meanwhile, a comprehensive assessment was made of possible requirements under different scenarios
.@MEAIndia: After having confirmed the availability of medicines for all possible contingencies currently envisaged, these restrictions have been largely lifted
Read 8 tweets
In times of crisis we need to behave in a responsible manner. We need to be responsible not only for ourselves but our family, friends and Society at large.

Public representatives who behave in an irresponsible manner should not be tolerated regardless of political affiliations.
A recent political Booze party with 600+ party workers. Inebriated party workers revelling in large gatherings.
Example of responsible behaviour by politicians.
As public representatives they are usually in contact with large no of people, putting everyone at risk. Self-immolation when in doubt is the responsible way. Image
Read 4 tweets
¿Es cierto que si tenemos #COVID19 no debemos tomar #ibuprofeno ? Hilo vía @dr_anamolina
Read 7 tweets

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