Discover and read the best of Twitter Threads about #Malaria

Most recents (24)

New from me, in @ConversationUK
"#Dengue in France: tropical diseases in Europe may not be that rare for much longer" theconversation.com/dengue-in-fran…

A bit like #scabies, we do have Neglected Tropical Diseases in Europe
#ntds #beatntds
(1/n)
Few dozen cases of local dengue transmission, more than has been observed before (bit of a theme for #infectiousdiseases in the recent past...)

An infected traveller would have returned to France, been bitten by a local mozzie, with onward transmission from biting new humans.
Seeing more mosquito-driven disease in Europe. Loads of #westnile virus in the lowlands in northern Italy, plus a few cases across other Euro countries
Read 8 tweets
Today is #WorldMosquitoDay!

Mosquitoes are the most dangerous animals in the 🌎🌍🌏 as they can transmit diseases such as:
🔸 Malaria
🔸 Dengue
🔸 Filariasis
🔸 Chikungunya
🔸 Zika
🔸 Yellow fever

🦟 borne diseases put the lives of billions at risk. Illustration of a mosquito ...
Today is #WorldMosquitoDay 🦟!

Over 600 000 people die from mosquito-borne malaria every year.

Sleeping 💤 under insecticide-treated nets is one of the most effective ways to prevent #malaria.

bit.ly/2tARuMY Mother and baby are in thei...
WHO recommends broad use of the first malaria vaccine (RTS,S) among children living in #malaria endemic areas with moderate to high transmission. The life-saving vaccine has been shown to have high impact in real-life use - to significantly ↘️ severe malaria, & ↘️ child deaths. Image
Read 8 tweets
PHOTOS: Buhari Inaugurates Anti-Malaria Council, Appoints Dangote As Chairman

The President, Major General Muhammadu Buhari (retd.) on Tuesday inaugurated Nigeria End Malaria Council in Abuja, ImageImageImageImage
noting that eradicating malaria would save Nigeria about N687 billion in 2022 and N2 trillion by 2030.
Buhari appointed the Chairman, Dangote Group, Aliko Dangote, as Chairman of the 16-member Council, stating that the strategy to tackle malaria had both public health as well as socio-economic benefits for Nigeria.
Read 4 tweets
Du coup, je suis en train de m'intéresser à la #MALARIA.

Vous saviez que la Chine s'était débarrassée de la malaria ?

Alors j'ai regardé comment ils ont fait.

Et je m'attendais à ce qu'ils disent qu'ils avaient organisé des distributions de tisane pour tout le monde...
1/8
who.int/fr/news/item/3…

...Et bien en fait ça a l'air un poil plus complexe que ça.
J'ai lu, hein. On parle d'accès au système de santé, de moustiquaires imprégnées d'insecticides...
Et aussi de traitements.
2
en.nhc.gov.cn/2015-12/07/c_4…

Voyez, là. Sur un site officiel chinois. Article daté de 2015. Vous avez un prix nobel de médecine chinois, Tu Youyou, qui avait mis au point un médicament à base d'extrait d'artémésia justement.
C'est très intéressant.
3
Read 9 tweets
The NIH's T.F. is employing the same tactic with LC research that he used when Covid first appeared.
Then, he realized that Sars CoV 2 had the chimeric spike protein with a furin cleavage site, identifying it as an NIH-funded/patented part of a UNCBaricLab/WIV collaboration on>
gain of function corona viruses.
T.F. sought to obstruct understanding of SC2 by
categorizing it as a completely novel virus and denying research into #EarlyTreatment with therapies like the Zelenko Protocol. Therapies which were known to be effective against vascular diseases>
like Malaria and against venom toxins.
This would've pointed to the engineered, chimeric nature of the virus.

A fact he was desperate to conceal.

T.F. is now obstructing funding for research which would confirm and advance the findings of #TeamClots and #IncellDx showing that>
Read 14 tweets
wereldwijde afname in kindervaccinaties afgelopen jaar, én het jaar ervoor 😢
Gemiddelde kindervaccinatiegraad 🌎🌍🌏 is gedaald van 86% naar 81%, met grote verschillen tussen landen.
"Dit gaat levens kosten", aldus @who
@WHO gebruikt de 3e #DTKP (difterie, tetanus, kinkhoest, polio) 💉als maat voor algeheel beeld vaccinatiegraad, maar de afname geldt ook voor #BMR waardoor de kans op #mazelen uitbraken wereldwijd ook toeneemt
#mazelen is de meest besmettelijke infectieziekte die we kennen
En het mazelenvaccin is het meest effectieve vaccin dat we kennen 💉
Toch gaan er jaarlijks 140.000 mensen (met name jonge kinderen) dood aan mazelen.

vaccinatiegraad moet dus ⬆️, niet ⬇️

who.int/news-room/fact…
Read 11 tweets
Very pleased to present our recent study of #endocytosis in #apicomplexans that draws on #K13 and drug-resistance in #malaria to learn of a highly unusual endocytic machinery in #Toxoplasma with a deep evolutionary origin. biorxiv.org/cgi/content/sh…
Using the #Plasmodium #artemisinin-resistance genes as initial leads, some proximity proteomics, and a good deal of super-res microscopy, a comprehensive molecular model of endocytic pits integrated into the cell’s complex (IMC) pellicle was achieved.
Remarkably, this superstructure is highly stable with the typically ephemeral proteins rigidly anchored at this site. Even more unusual, the complex is preassembled in daughter cells before the plasma membrane is even recruited. (and yes, Toxo daughter cells ARE gorgeous!)
Read 12 tweets
"I thank all Member States for your hard work over the past week. As always, you have dealt with a large agenda."-@DrTedros #WHA75
"You have adopted landmark decisions and resolutions on sustainable financing;
On strengthening health emergency preparedness and response; "-@DrTedros #WHA75
Read 21 tweets
LIVE: Second Plenary meeting at #WHA75 twitter.com/i/broadcasts/1…
"Yesterday, I made my remarks on the theme of health for peace and peace for health, which Member States will discuss in the general debate. I want to start today by looking back, to where we have been over the past five years"-@DrTedros #WHA75
@DrTedros "You elected me 5 short years ago, with an ambitious agenda for universal health coverage; health emergencies; women's, children's and adolescents' health; the health impacts of climate and environmental change; and a transformed WHO"-@DrTedros #WHA75
Read 58 tweets
The 🆕 WHO Results Report is out!

Learn how we responded to health challenges & emergencies around the world 🌍🌎🌏 in 2020-2021.

👉bit.ly/ResultsReport2… Image
+People living w/ better health & well-being
▓▓▓▓▓▓▓▓▓░ >900M

+People better protected from emergencies
▓▓▓▓▓▓▓▓▓░ >920M

+People benefiting from Universal Health Coverage
▓▓▓░░░░░░░ >270M

Our goal is to achieve 1⃣ billion people/target by 2023.
As the world’s global health guardian, fulfilling these triple billion targets will be our main goal as a measurable means of reducing health equity gaps and ensuring #HealthForAll.

More info 👉bit.ly/3NeX3aO Image
Read 7 tweets
Today is #WorldMalariaDay.

#DYK: we can prevent and cure #Malaria?
Learn about the symptoms so you know when to get help from a healthcare professional bit.ly/3rF1djY
#Malaria is transmitted through the bites of Anopheles mosquitoes🦟
In 2020, nearly half of the world's population was at risk of malaria bit.ly/3rF1djY
Early diagnosis & treatment of #malaria reduces disease, prevents deaths and contributes to reducing transmission bit.ly/3rF1djY
Read 8 tweets
1/ 🧵Hello #medtwitter Ready for some NephMadness? 🤯
Not just any madness, but beware your mosquito bites 🦟, because today’s topic is #Malaria and kidney involvement.

#NephTwitter #NephMadness
@NephMadness
2/ 🧵 Where does the word malaria originate from?

PMID: 11053494
3/🧵 Malaria is an Italian word composed of “mala” and “aria,” meaning bad (malus) air (aeris). It was first used to describe a fever (miasma) mistakenly attributed to exposure to poisonous air.
PMID: 11053494, 9641206
Read 19 tweets
#disease risks in the new #IPCCReport

Climate change and variability are facilitating the spread of:
- #chikungunya virus in North, Central and South America, Europe and Asia
- tickborne #encephalitis in Europe
- #RiftValleyFever in Africa
- #WestNile fever in south- eastern Europe, western Asia, the Canadian Prairies, and parts of the USA
- #LymeDisease vectors in North America and Europe
- #Malaria in East and Southern Africa
- dengue globally
#Dengue risk will increase with longer seasons and wider geographic distribution in Asia, Europe, Central and South America and sub-Saharan Africa, potentially putting additional billions of people at risk by the end of the century
Read 5 tweets
𝟭𝟵𝟴𝟬:Wojciech “Al” Krotoski et al publish a report in the British Medical Journal describing a dormant liver stage of #Plasmodium cynomolgi in Rhesus macaques. These dormant liver stages, called "hypnozoites" are postulated to be the cause of relapses of this #malaria species Image
- Image references: ncbi.nlm.nih.gov/pmc/articles/P…; ajtmh.org/view/journals/…
- References: https://t.co/QDyaZSACDa; https://t.co/zzZPG6Ze3M; link.springer.com/article/10.100…
𝟭𝟵𝟴𝟭: In 1981, Dr William C. Campbell of the Merck Institute for Therapeutic Research in the US, published "An Introduction to the Avermectins" which described a new series of compounds with potent antiparasitic properties against nematode & arthropod #parasites. Image
Read 88 tweets
𝟭𝟵𝟳𝟯:In 1973, Thomas A. Miller of the University of Glasgow Vet School, had his canine hookworm (Ancylostoma caninum) vaccine approved for commerical use in the US. Though discontinued in 1975, Miller's work has informed hookworm vaccine research to this day! @BAVet_Parasitol Image
𝟭𝟵𝟳𝟰: In Oct '73, Dr Dan Jones of the Bascom Palmer Eye Institute in Miami introduced Acanthamoeba spp. as a human ocular pathogen to a meeting of the Ocular Microbiology & Immunology Group in the USA. Months later, in 1974, Nagington et al. would publish the 1st case studies Image
Read 9 tweets
𝟭𝟵𝟳𝟬: It was in 1970 that the full life cycle of #Toxoplasma gondii was described for the 1st time by Frenkel et al. Nowadays, the micro- and macro- gametocyte stages in the cat intestine are rarely studied, so the Frenkel et al. (1970) micrographs are still informative. Image
𝟭𝟵𝟳𝟭: A year that would forever change the field of #malaria research. In 1971, Prof Youyou Tu of the China Academy of Chinese Medical Sciences in Beijing, would use ether to extract "qinghaosu" from Artemisia annua L. leaf extract. In English: Artemisinin. @womeninmalaria Image
Read 7 tweets
In 𝟭𝟵𝟲𝟲, the eminent parasitologist P. Cyril C. Garnham published his "magnum opus", the 1132-page encyclopaedia of #malaria parasites, "Malaria Parasites and Other Haemosporidia". After 56 yrs, images from this book are still used as references across the world. #Plasmodium Image
𝟭𝟵𝟲𝟳- what a year! In 1967, Ruth Nussenzweig & colleagues released a @Nature paper showing that X-irradiated Plasmodium sporozoites produced protective immunity against #malaria in mice. This study sparked research that would result in the identification of CSP (1/3) Image
Read 11 tweets
Sehr schwer zu vermitteln, aber wichtig: *JEDE* #Impfung hat das Potential, eine Infektion komplett zu unterbinden– keine ist dabei perfekt. Extrem gut: #Masern-Impfung; nicht sonderlich gut u.a.: #Malaria, #Influenza, #COVID19. Abgesehen von kompletter… 1/3
…Verhinderung der Infektion („sterile Immunität“) schaffen es Impfungen aber, den zu zu erwartenden Verlauf der Krankheit abzumildern und abzukürzen. Dadurch bestenfalls auch verminderte Möglichkeit der Weitergabe (weniger Erregerlast, kürzere Dauer), aber auf jeden Fall… 2/3
…verminderte #Krankheitslast in einer geimpften Population. Wie wichtig das sein kann, siehe z.B. auch Diskussion um Malaria-Impfung ⬇️.

Schwarz-weiß ist in der Biologie fast nichts, aber auch ein Grau kann schon eine große Wirkung haben!

swr.de/wissen/wie-gut…
Read 3 tweets
Who's ready for another jab in March? Roll up your sleeve (again) for #Pfizer 1.1:

CEO Albert Bourla, Jan 10, 2022: "And we know that the 3, the 2-dose[s] of the #vaccine, offer very limited protection, if any."

#4IR #BiotechEconomy #GeneEditing #mRNA #Crispr

Thread 👇
Bourla con't: "The 3 doses w/ the #booster, they offer reasonable protection against hospitalization & deaths... Now, we are working on a new version of our vaccine, the 1.1 [] that will cover #Omicron as well."

Bourla: "... we are waiting to have the final results. The vaccine will be ready in March, & [] we'll be able to produce it massively."

Yahoo: "I want to quickly talk about the #kids... under 5... the company has said that it's going to need to be a 3-dose vaccine..."
#biotech
Read 6 tweets
The Abecedarians, the first band alphabetically in my collection. I’m not sure I have listened to this since I bought it. Fac 117, is a 12” 45, just two tracks, electronic with nods to other Factory bands. No idea what happened to them.
#abecedarians #factory #factoryrecords ImageImage
Backstory: In an effort to listen to a wider variety of the music I own for the first half of this year I’m dedicating a week to each letter. I thought I’d start with the disc that has sat leftmost on the shelves since some time in the eighties!
A Certain Ratio. A couple from them today, between the two marking a huge change from fucked to funky.

#factory #factoryrecords #acr #acertainratio
Read 267 tweets
"It’s a pleasure to welcome our friends from the Palais back to WHO.
The last time we hosted you, in July last year, none of us could have imagined that almost 18 months later, we would still be in the grip of the pandemic."-@DrTedros, media briefing for Geneva-based journalists
"More than 3.3 million people have lost their lives to #COVID19 this year – more deaths than from HIV, malaria and tuberculosis combined in 2020.
And still, COVID-19 continues to claim around 50,000 lives every week."-@DrTedros
"That’s not to mention the unreported deaths, and the millions of excess deaths caused by disruptions to essential health services."-@DrTedros
Read 41 tweets
#COVID19 pandemic has disrupted #malaria services, leading to a marked increase in cases and deaths: 14 million more cases in 2020 compared to 2019, and 69,000 more deaths - new report.
➡️bit.ly/3IlXxu9

#EndMalaria Image
Approximately 2 in 3 of these additional deaths were linked to disruptions in the provision of #malaria prevention, diagnosis and treatment during the pandemic bit.ly/3IlXxu9 #EndMalaria
Sub-Saharan Africa continues to carry the heaviest #malaria burden, accounting for about 95% of all malaria cases and 96% of all deaths in 2020.
About 80% of deaths in the region are among children under 5 years of age bit.ly/3IlXxu9 #EndMalaria Image
Read 4 tweets
#immunosuppression

IMMUNE CONTROL POINTS AND COVID-19

✅IMMUNOLOGIC CONTROL POINT MOLECULES ARE #INHIBITOR RECEPTORS EXPRESSED IN IMMUNE CELLS THAT TRIGGER IMMUNOSUPPRESSOR SIGNALING PATHWAYS.
These molecules are crucial to maintaining self-tolerance. 👉SIGNALING THROUGH THESE MOLECULES MAY TAKE IMMUNE EFFECT CELLS (ESPECIALLY T CELLS) TO A STATE KNOWN AS "DEPLETION". T cell depletion is defined by reduced effector function, poor memory responses
👉 due to sustained expression of immune checkpoint molecules (such as PD1, # CTLA4, # LAG3 ...). There are numerous types of activating and inhibitory interactions that occur between antigen presenting cells (APC) and T cells and thus regulate the nature of immunity.
Read 28 tweets

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