BREAKING NOW: CHINESE RESEARCHERS SAY #CORONAVIRUS HAS A HIV-LIKE SECTION WHICH MAKES ITS ABILITY TO BIND TO HUMAN CELLS 1,000 TIMES THAT OF SARS
The "mutation" could not be found in Sars, Mers or Bat-CoVRaTG13, a bat coronavirus that was considered the original source of the new coronavirus with 96 per cent similarity in genes
Scientists showed that SARS entered the human body by binding with a receptor protein called ACE2 on a cell membrane. And some early studies suggested that the new coronavirus, which shares about 80 per cent of the genetic structure of Sars, might follow a similar path.
But the ACE2 protein does not exist in large quantities in healthy people
Other highly contagious viruses, including HIV and Ebola, target an enzyme called furin, which works as a protein activator in the human body.
Other highly contagious viruses, including HIV and Ebola, target an enzyme called furin, which works as a protein activator in the human body.
Many proteins are inactive or dormant when they are produced and have to be “cut” at specific points to activate their various functions.
the HIV-like "mutation" can generate a structure known as a cleavage site in the new coronavirus’ spike protein.
the HIV-like "mutation" can generate a structure known as a cleavage site in the new coronavirus’ spike protein.
The virus uses the outreaching spike protein to hook on to the host; normally this protein is inactive.
The cleavage site structure’s job is to trick the human furin protein to cut and activate the spike protein and cause a “direct fusion” of the viral and cellular membranes.
The cleavage site structure’s job is to trick the human furin protein to cut and activate the spike protein and cause a “direct fusion” of the viral and cellular membranes.
Compared to the SARS’s way of entry, this binding method is “100 to 1,000 times” as efficient, according to the study.
Just two weeks after its release, the paper is already the most viewed ever on Chinarxiv.
Multiple other studies worldwide confirm or support the findings.
Just two weeks after its release, the paper is already the most viewed ever on Chinarxiv.
Multiple other studies worldwide confirm or support the findings.
The #coronavirus has an HIV-like 'mutation' that means its ability to bind with human cells could be up to 1,000 times as strong as that of SARS
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