Discover and read the best of Twitter Threads about #COPD

Most recents (24)


Yesterday we published our first combined asthma and COPD 'Drawing Breath' @NACAPaudit report.

I thought I'd highlight a few key themes.

First, it's important to note that these data reflect care during the pandemic period when front line clinical teams were stretched...
We have four key recommendations, each relevant to #asthma in adults, asthma in children and young people and #COPD, including #PR services.

The first area is that everyone should be able to access early and accurate diagnosis. Here are some key findings; we need to do better:
The second theme is the need for TIMELY care when a person has been admitted to hospital, for example receipt of systemic steroids in asthma, or #NIV in COPD for those who need it.
Read 11 tweets
Bench to bedside series: Lung COPD part 1/3
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Bench to bedside series: Lung COPD part 3/3
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #MedEd
Read 4 tweets
Healthy Lung vs. Lung with Chronic Obstructive Pulmonary Disease (COPD)
h/t @PatologCritica
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #lung #COPD #INNOMed

Bench to bedside series: Lung COPD part 1/3
Respiratory histology (via @drawittoknowit)
Health & COPD Lung @TheLancet
#4KMedEd #meded #foamed #medtwitter #MedEd #MedTwitter #Pulmtwitter #scRNAseq #Bioinformatics
Read 5 tweets

Creating awareness for the public on the key factors which influence the lung development till adulthood and sharing the ways to keep the lungs healthy is important.

Because we all have only one set of lungs. (1/n)

This is a new term introduced recently which highlights the 'complex and dynamic' interactions between #Genetics and #Environment over #time which plays the crucial role in the development of #COPD (2/n)
When i was a resident, I was taught that #Cigarettesmoking contributes to ~90% of COPD burden in the world.

But now the data suggets that more than half of COPD burden, worldwide is due to causes other than tobacco. Why? What has changed? (3/n)
Read 19 tweets
👀it’s out! The llatest 2023 @GOLD_COPD guidance has been released...

🌟There are BIG changes this year. Here are my first thoughts… but lots to digest:

1. Revised #COPD defn
2. Etiotypes
3. ABCD is out, ABE is in
4. Farewell ICS-LABA
5. New exacerbation defn

1. Definition of COPD now *includes* emphysema…

'heterogeneous lung condition characterized by chronic respiratory symptoms due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction’
An alphabet soup from COPD-A (asthma), through 'C (cigarette smoking), 'D (abnormal lung development) and 'G (genetic #alpha-1), to 'I (infections), 'P (pollution) and U (unknown).

What do you make of this? A similar approach has helped in pulmonary hypertension!
Read 7 tweets
#November2022 #November12 #WorldPneumoniaDay #LungCancerAwarenessMonth #LungCancerScreeningDay

This 'long' thread is about-

"Lung Cancer Awareness month- Nov"
"World Pneumonia Day- Nov12"
"National Lung Cancer Screening Day- USA: Nov12"
The International Agency for Research on Cancer (IARC) is taking the opportunity this November, Lung Cancer Awareness Month, to highlight the burden and principal risk factors of lung cancer around the world.
1.8 million (18 lakh) people died in 2020 due to this cancer (2/21)
This count is almost double the number of deaths caused by the 2nd most common cause of cancer deaths - colorectal cancer!!

Tobacco smoking is the most common cause of lung cancer

Smoking in public places exposes those who are not interested in smoking .. (3/21)
Read 23 tweets
NEXT :: COPD - Oriole Roca.
Evidence : NIV is great for acute COPD. The classic from Laurent Brochard
but if beyond 24 hours. alternative is High flow nasal cannulae.
@ESICM NIV failure - intubat the patient, COPD patient intubated, Vol Control, 7ml/kg PBW, I:E = 1:4 , RR 20. Then patient is "hypotensive". why?
Read 20 tweets
(1/9) #COPD is extremely common among people who use heroin. We studied treatment and outcomes in this important patient group. Diagnosis is often late, and the risk of exacerbations is double that of other patients. New research in @BMJMedicine…
(2/9) We studied a large cohort of >100k people with a history of using heroin and other illicit opioids in England. In this cohort, the rate of death with a primary cause of COPD was 15x greater than for people of the same age in the general population.
(3/9) Approximately 4,000 people in this cohort were diagnosed with COPD by their GP. We matched each with 5 other patients of the same age and sex at the same GP surgery who were also diagnosed with COPD, but did not use illicit opioids.
Read 11 tweets
Bench to bed series: Lung COPD part 3/3
#scRNAseq paper: Human distal airways contain a multipotent secretory cell that can regenerate alveoli
1. RASCs (new cell-type) + #stemcell properties in distal airways 2. faulty RASC-to-AT2 transformation in COPD
#Bioinformatics #meded Image
Read 4 tweets
Today, @AsthmaIreland made a public statement in support of Minister @EamonRyan's proposed Solid Fuel Regulations. We called on all parties to support the regulations in a bid to end the 1,300 premature deaths caused annually by fine particle emissions from burning solid fuels.
The new regulations would ban smoky coal and wet wood, and prohibiting the commercial sale of sod turf, will save lives, but provide for continued turf extraction by those with turbary rights and distribution within small communities. @Dept_ECC
Air pollution can cause as well as exacerbate #chronicillness like #COPD, #asthma, heart disease and #stroke, #cancer, #diabetes and #dementia. Irish clinical research also links spikes in air pollution with increased hospital admissions for asthma and heart disease @roinnslainte
Read 10 tweets
The Wife is at the hospital for emergency tests (not COVID). I am trying to work, which feels impossible.
I would very much appreciate prayers from those who pray and healing energy from those who don't. (I'm religious, she's an atheist.) Thank you.
We got another test result update today from our fab primary practice. The Wife has no lung disease,which was a serious concern,as she is a recovered smoker & has had a severe lingering cough for months since she had a fall at school in late Nov.(that caused the rib fractures).
We are still waiting on another round of test results due next week on other symptomology, but knowing that The Wife does not have COPD or lung cancer is huge. Thank you again for all your support and well wishes. We are both so appreciative.
Read 4 tweets
🧵on basic #inhaler technique b/c we can all do better educating our #copd #asthma patients 🫁

Studies show inhaler error is common & many pts aren’t taught how to use their inhalers properly

↑💊 ≠ always the answer

#MedTwitter #MedStudentTwitter #Tweetorial
Step 1: Actually ask how they use their inhaler😅

With so many types, it’s not surprising pts & providers get confused 😵‍💫

Esp in clinic, ⏰ is tight. But only takes a min to explain

Also pharmacists/RTs are amazing! I <3 using them when able

Let’s first discuss the common inhaler devices. Which one was used in the clip above?

Read 23 tweets
If nicotine vapes ("e-cigarettes") are, in fact, safer than smoking, and help smokers quit, they are (obviously) profoundly different from recreational drugs like alcohol, caffeine & cannabis.

So, what if we just ask ex-smokers who vape how they're doing?

Among ex-smokers who quit by switching to nicotine vapes, 93% say their health improved. 62% say "improved dramatically." The 5% who said "no change" said "I was healthy to begin with."

Healthier. This is so different from daily screaming headlines.
Among ex-smokers who quit by switching to nicotine vapes ("e-cigarettes"), 90% say they now have fewer and less sever lung infections. We're healthier. Does no one care?

Confirmed by these peer-reviewed studies.……
Read 7 tweets
World class ⁦@ClevelandClinic⁩ Hospital Medicine Grand Rounds - Update in #HospitalMedicine by Dr. Jessica Donato! A rising star! ⁦@BIDMC_IM⁩ ⁦@HarvardHospMed⁩ ⁦@CWRUSOM⁩ ⁦@SocietyHospMed
Is postop #afib associated w increased risk for CVA/TIA?
Is one #DOAC better than other for #afib?
Read 21 tweets
Listen to this and let’s reflect as a respiratory community how we can emulate #cardiology and transform outcomes in #asthma, #COPD, #bronchiectasis, #ILD +other chronic #respiratory diseases over the NEXT 50 years. This accompanies a great @nejm Perspective by @EricTopol. Think:
Cross-disciplinary interchange of ideas...integration of basic science and translational research...technological innovation...EBM...large cohorts...policy change...huge collaborative trials...adequate research funding...genetic insights...drug development... life-course...
...precision determinants of health...biomarkers...AI...

Respiratory #pulmonology - we need to be more bold.
Read 3 tweets
#McKinsey Data visualizations from "Charting the Path to the Next Normal". "Globally, governments allocated a stunning $10 trillion for #economic #stimulus in just two months. That was triple what they spent during the entire 2008–09 financial #crisis."…
"#Digital became the way to get many things done—from visits to doctors to shopping to #socializing. The reliance by Asian governments & businesses on six digital & mobile technologies would become a model for the world."

#4IR #5G #GreatReset #telehealth
#McKinsey is a World Economic Forum strategic partner.
On Jan 25-29, "The #Davos Agenda", will focus on "the future of work, accelerating stakeholder capitalism, & the Fourth Industrial Revolution." #Social, #human & "natural capital".

Read 7 tweets
What Skerrit is saying in regard to not bringing #tobacco under the prescription model is complete rubbish. The @TGAgovau site explicitly mentions novel #nicotine products - #SLT & #HTP.
Huh.. @hollieahughes just said they're due to report by /18th/ December. I'd thought it was the 1st of December.
Emily Banks 'sum total of world experience' .. yeah, with some heavy #CherryPicking.
The Oz #ANTZ /all/ seem to be loving 'the #GatewayEffect' which is a 'real thing'.. 🙄
Read 137 tweets
Absolutely. Buzzing.

Zoom call with @SFoodbanks, @IanByrneMP, and @Kartik__Raj #righttofood (wow)

These guys are REAL heroes and they dont even know it - their hard work and passion keeps families afloat, and dignity intact, and here's a thread about the importance of this:
2 Adversity hits the poorest hardest - and that includes natural disasters, accidents like Titanic, and austerity: cuts per head are highest for places with the sickest people, especially in the North. Infants of families who are in poverty are more likely to die.
3 We know from @CPAGUK and others that rates of child poverty are unacceptably high - around 1 in 3 kids pre covid, and who knows what now... and that poverty impacts the things we take for granted - birthday presents, school uniform, and even food
Read 13 tweets
My system has been firing for hours since I first saw this thread show up in my feed. I feel absolutely furious that people are misrepresenting #ACEsScience as determinant & dismissing it as unethical & faulty. No one with any reputability is saying "I am my ACEs." #WhyITalkACEs
Maybe you haven't been affected by your experience of #ACEs Maybe you had enough mitigating experiences of #BCEs or #PCEs Maybe you pulled yourself up by your bootstraps. Maybe you were able to access resources in early adulthood to prevent or redirect long term effects.
Maybe the effects of your #ACEs and #ChildhoodToxicStress just haven't shown up in your physiology yet. #Cancer #HeartDisease #Diabetes #COPD #Obesity #AutoimmuneDisease #Suicide #Depression have all been shown to also occur in people with histories of #ChildAbuse #ChildNeglect
Read 13 tweets
#CO2 #Rückatmung unter der #Maske - ein Mythos ?
Nein, wahrlich nicht. Hier ein relativ aktuelles Video aus Österreich, es gab schon seit Monaten diverse Videos im Internet dazu, die den Anstieg der CO2 Konzentration auf das 30-50fache innerhalb weniger
Minuten belegen. Die Luft enthält im Freien rund 0,04% CO2 und im Körper wird durch #Sauerstoff und deren Umwandlung in Energie in den Zellen CO2 erzeugt und über die Ausatmung entsorgt (enthält das 100-fache mit rund 4,0%). Bereits in Innenräumen hat man erhöhtes CO2 und der
der Grenzwert auch im Arbeitsschutz liegt bei 0,5% für Dauerexposition oder 1,0% in einer 15 Minuten Periode. Das gilt für Arbeitsplätze, an denen eine höhere CO2 Exposition möglich und wahrscheinlich ist, zeigt aber, wie gefährlich CO2 eingeschätzt wird.…
Read 6 tweets
#COPD=3rd leading cause of death🌍 Symptoms mean exercise is hard but essential for health‼️ My thesis = Experiences of using apps&wearables for monitoring #physicalactivity: People with #ChronicObstructivePulmonaryDisease & healthcare practitioners⌚️📱1/3 #CovUniTweCon @CU_ReCap Image
2/3 Activity monitors are widely used to try & increase activity, but do they really work?🤔Apparently they can increase motivation & awareness of #physicalactivity 📱⌚️I’ve interviewed people with #COPD about their experiences of using apps & wearables🗣️💭#CovUniTweCon @CU_ReCap Image
3/3 Then I spoke to healthcare practitioners about what they think of #COPD patients using tech (📱⌚️) in practice 🗣️ From understanding experiences, we can improve interventions using apps/wearables & hopefully increase activity levels for better health👍 #CovUniTweCon @CU_ReCap Image
Read 3 tweets
Excited to share our work using single-cell RNA sequencing to profile the lung parenchyma in advanced COPD. Follow 🧵for highlights and new #COPD insights…
Manuscript is co-authored with @jmcdonou, w/ leadership from @KaminskiMed @YalePCCSM and Ivan Rosas @bcmhouston and important contributions from Taylor Adams, Neeha Kothapalli @Yale @ptimshel @jonas_schupp @caroymalo @JLGomezMD @SergioPoli @mauchioccioli & others not on twitter
We identified major cell types from 15 control donor lungs and 17 explanted lungs from COPD patients requiring transplant and builds on the previous study by Adams et al…
Read 11 tweets
Impressive work by @ahti_Ams.
A dashboard which predicts (or visualises) hospital admissions and ICU admissions as the #SARSCoV2 infection rate goes up.
Granular view of all #Dutch municipalities.
#covid19nl Image
This dashboard enables you to see the course of #covid19 based on the risk factors in that particular region or municipality.
Risk factors- #age, livability index, multiple generations cohabiting, #asthma, #COPD and #diabetes type 2.
The basis for this dashboard is this research paper from @BMCMedicine from #UK.
Interesting risk prediction visualization @mzelst @edwinveldhuizen?…
Read 3 tweets
I'm very concerned about the rising rates of #COVID19 in AZ, TX, etc. So here is my rant about masks. 1/n
I'm a lung doctor and I feel like I know a lot about oxygen. For example, see here:…
Read 12 tweets

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