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Jan 24 • 4 tweets • 2 min read
1/3 "We report reduction in proportion of hospitalisations and deaths from SARS-CoV-2 infections during the Omicron variant dominated wave in Malawi, in the context of high SARS-CoV-2 seroprevalence and low COVID-19 vaccination coverage."

thelancet.com/journals/eclin…
2/3 "These findings suggest that COVID-19 vaccination policy in high seroprevalence settings may need to be amended from mass campaigns to targeted vaccination of reported at-risk populations."
3/3 What about vaccine non-responders? What about those who have not seroconverted despite exposure? How many of the study participants were reinfected? How many are victims of viral reservoirs and/or viral persistence? What about latent post-acute sequelae of #SARSCoV2?
#Malawi #COVID19 #CovidIsNotOver #Omicron

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More from @TaNaishaJ

TaNaisha NOT MILD Lee Profile picture
Jan 25
1/9 Exciting work from Simona Nitti and colleagues... good news for #space #weather forecasting/predictions and correlated #disaster #preparedness, #bioterrorism, #pandemic preparedness, #power #outages, #cybersecurity, etc.

academic.oup.com/mnras/article-…

#heliobiology
2/9 "#Coronal #holes (#CHs) are the source of #high-#speed #streams (#HSSs) in the #solar #wind, whose interaction with the slow solar wind creates #corotating #interaction #regions (#CIRs) in the #heliosphere."
3/9 "Whenever the CIRs hit the #Earth, they can cause #geomagnetic #storms. We develop a method to predict the strength of CIR/HSS-driven geomagnetic storms directly from #solar #observations using the CH areas and associated #magnetic #field #polarity."
Read 9 tweets
TaNaisha NOT MILD Lee Profile picture
Jan 25
1/4 "In this cohort study, more #severe acute illness, a higher #Charlson #Comorbidity #Index score, and being #unvaccinated were associated with a higher risk of reporting #COVID19 symptoms lasting 28 days or more."

#Unvaccinated and #immune naive or #convalescent?
2/4 "Participants with #COVID19 were more likely to seek medical care for #diabetes, #pulmonary, #neurological, and #mental health–related #illness for at least 6 months after onset compared with their pre-#COVID #baseline health care use patterns."
3/4 "These findings may inform the risk-benefit ratio of COVID-19 #vaccination #policy."

#SARSCoV2 #CovidIsNotOver #PASC #LongCovid

All were not checked for viral reservoirs and/or persistence, not tested in upper and lower respiratory tract and in the gastrointestinal tract.
Read 4 tweets
TaNaisha NOT MILD Lee Profile picture
Jan 25
1/5 Fascinating work from Jae-Hyun Yang and colleagues on #mammalian #aging, published in Cell...

An abstract thread 🧵...

"All living things experience an increase in #entropy, manifested as a loss of #genetic and #epigenetic information."

cell.com/cell/fulltext/…
2/5 "In #yeast, #epigenetic information is lost over time due to the relocalization of #chromatin-modifying proteins to #DNA breaks, causing cells to lose their identity, a hallmark of yeast #aging."
3/5 "Using a system called “#ICE” (#inducible changes to the #epigenome), we find that the act of faithful #DNA #repair advances aging at #physiological, #cognitive, and #molecular #levels, including #erosion of the #epigenetic #landscape,..."
Read 5 tweets
TaNaisha NOT MILD Lee Profile picture
Jan 25
1/14 #Men and #women experience disease differently. This is reminiscent of #SyndromeX and other chronic disease like #MECFS, #slow #virus manifestations, and even #LongCovid and post-acute sequelae of #SARSCoV2.

A thread summary article 🧵

anu.edu.au/news/all-news/….
2/14 "#Women are up to 75 per cent more likely to experience #adverse #reactions to #prescription #drugs than #men because of a range of differences in #traits between the #sexes, according to a new study from The #Australian #National #University (#ANU)."
3/14 "The researchers believe more should be done to take this into account when treating #diseases."
Read 16 tweets
TaNaisha NOT MILD Lee Profile picture
Jan 24
1/4 "... findings suggest #organizational #priorities can potentially #disturb #natural #patterns of #gestation and #birth #timing..."

journals.plos.org/plosone/articl…
2/4 "... with a potential to improve U.S. #perinatal #outcomes with organizational models that more closely resemble those of #England and the #Netherlands."
3/4 "In the U.S., however, a decidedly different pattern emerged. #Vaginal #births without #induction or #augmentation in U.S. hospitals were far more likely to occur during #standard #working #hours."

#infant #neonates #prenatal #perinatal #health #outcomes #maternal
Read 4 tweets
TaNaisha NOT MILD Lee Profile picture
Jan 24
1/3 "While one of #Geotail’s two #data #recorders failed in 2012, the second continued to work until experiencing an #anomaly on June 28, 2022. After attempts to remotely repair the recorder failed, the mission operations were ended on November 28, 2022"

nasa.gov/feature/goddar…
2/4 "With an orbit that took it as far as 120,000 miles from Earth at times, #Geotail helped provide complementary data from remote parts of the #magnetosphere to give scientists a complete picture of how events seen in one area affect other regions."
3/4 "#Geotail also paired with observations on the ground to confirm the location and mechanisms of how #aurora form."

#magnetosphere
Read 6 tweets

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