Discover and read the best of Twitter Threads about #Mild

Most recents (19)

Mit der #SARS-CoV-2 #Omicron-Variante infizierte #Kinder können neurologische Komplikationen entwickeln - Unsere (Hamster) Studie deutet darauf hin, dass SARS-CoV-2 das #Gehirn in jungen Jahren ua in bis zu 75% durch neuronale Degeneration beeinträchtigt. #genaumeinHumor #mild
Modell: Intranasale Infektion mit SARS-CoV-2 Omicron-Varianten kann entzündliche Hirnschäden bei jungen Hamstern hervorrufen.
Frisch abgesetzte Hamster wiesen eine höhere Viruslast im Gehirn, eine signifikant erhöhte Liquorkonzentration von TNF-α und CXCL10 sowie entzündliche Schäden auf, darunter eine leichte Meningitis und eine parenchymale Gefäßstauung, und das ....
Read 8 tweets
1/2 Compelling share from @oliver_phil...

"Remarkably, previously #hospitalized and #nonhospitalized patients remained with decreased numbers of CD1c+ #myeloid DCs and pDCs seven months after #SARSCoV2 #infection."

#COVID19 IS NOT #mild
2/2 "Moreover, the expression of #dendritic #cell (DC) markers such as #CD86 and #CD4 were only restored in previously #nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed."

Read 5 tweets
"Sinds eind maart 2022 waren er vrijwel iedere week meer doden dan verwacht, constateert het CBS. Rond die periode begon een griepgolf die ongeveer drie maanden duurde".

@nos: omicron golf begon precies die periode…
in voorjaar 2022 was er een bescheiden #griepgolf die niet eens boven de epidemische grens uit kwam @Nivel_research

tegelijkertijd was er een grote #omicron golf, met steeds minder betrouwbare "Test-data" omdat de PCR na april in veel gevallen niet meer nodig was in die tijd
de @who maakt zich grote zorgen over de nog steeds voortdurende sterfte aan #COVID19

wellicht ons #NieuweNormaal?

Read 5 tweets
Even #mild #COVID #infection increases risk of #blood #clots and #death

A study in the UK found that mild (non-hospitalized) infections led to a 2.7x higher risk of blood clots and 10.2x higher risk of death compared to controls (… ). H/T: @LauraMiers 🧵1/ Chart showing hazard ratio of mortality and various cardiova
The study looked at 17,871 COVID-19 cases in the UK between March 2020 and March 2021. People hospitalized *for* COVID-19 were at even higher risk:
118.0x = All-cause Death
27.6 = Venous Thromboembolism (blood clots)
21.6x = Heart Failure
17.5x = Stroke

14.9x = Atrial Fibrillation (AF)
13.6x = Pericarditis
9.9x = Myocardial Infarction (heart attack)

Read 22 tweets
Plain text:

#Children and/or #teenagers are not the 'drivers' of the 'infections'. Not even day care centers or schools.

The drivers of the #infections, currently #RSV, #influenza and #corona #SARSCoV2 , are #adults in the western world. They go to restaurants, clubs, bars,
football stadiums, concerts, and always without #FFP2 !

Because in the western world, wearing a #mask is seen as something bad and is accordingly badmouthed. It is conveyed how, for example, only very #anxious people would wear a mask. Or wearing a mask is exaggerated, after all
everything is #harmless and #mild. Practically just a #sniffle! (No, #RSV, #influenza + #corona #SARSCoV2 are not harmless #colds)!

So if you are looking for someone to #blame for the infection, you should pause for a moment and think about your own #behavior.
Read 8 tweets
#covidlong #PEC #inegalites
@ArsBretagne je suis profondément choquée de la description - partielle et donc partialle, que fait le professeur en charge de l'unité #CL dans cette vidéo que @OuestFrance diffuse.
Même si elle évoque le retentissement sur la vie professionnelle et familiale des patients concernés, évoquer des *symptômes pas sévères en soi" (sic) est déplacé. Surtout pour une professionnelle qui doit savoir que la chronisisation des #SFPI/#SFPV (symptôme de fatigue post
viral / infectieux) va être facilitée par une réadaptation à l'effort que les patients ne toléreraient pas. A cet égard, son équipe pluridisciplinaire doit veiller à modifier les soins si des #MPE (malaises post effort) se déclarent. Parce que ces MPE sont le symptôme
🧵 3
Read 7 tweets
Small thread on why I think we will see a bigger outbreak of #monkeypox d/t #COVID19 .We know Covid causes T cell response suppression in some & also complement mediated injury leading to effective reduction in levels of complements (hypocomplementemia) ctd)@fitterhappierAJ ctd)
2/n We know for a fact that at least in kids the complement induced injury caused hypocomplementemia in young , this was one of the pathways of acute liver injury in some kids , if the complement system is exhausted
doi: 10.1097/INF.0000000000002804. PMID: 32639461.
@medriva @VirusesImmunity @britsocimm @KunstJonas @ManojShukul @Kanupriya78 @kumarmanish9 @RonaldKlain @G_LaryeaAdjei @amrit_lohia 3/n We also know that #Covid causes direct infection of T cells and leads to lymphopenia , we need to understand that post #Covid the T lymphocytes arent there to save infection ctd) .
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Les effets connus et documentés du #CovidIsNotOver aka #COVID19 à long terme. Thread traduit ⏬⏬⏬
1/ Désormais les sequelles du #covid19 sur le coeur, le cerveau, les poumons, le système vasculaire, le système sensoriel, les reins etc..sont de mieux en mieux compris.
1/ Encore aujourd'hui, toute certitude qu'une infection massive de la population est "OK" est un pari - pari dont les coûts à long terme sont inconnus
Read 18 tweets
The story of #Mild #Omicron Part 1
Long Thread -Story of 8 countries
Italy- Deaths due to Omicron have been higher than Delta by miles and almost reaching prevaccination levels .Vaccines were released around end December- Early January in most countries #OmicronIsNotMild ctd)
Ctd2)Denmark is second country- Again the Delta was decimated by the vaccines BUT with the Omicron the deaths have reached almost pre vaccine deaths #OmicronIsNotMild, #Omicron, #OmicronVariant , Also the Danes like others opened up after reaching good vaccination levels .
Ctd3) Country 3- Canada -Here too #Omicron crossed the deaths due to Delta by miles , reaching number of deaths before vaccination, in fact overshooting that number
#OmicronIsNotMild , needless to say the Canadians are fed up because it is #Mild in the media
Read 12 tweets
Day 3 of #Omicron symptoms was my worst so far, with fatigue & a very heavy head, alongside sneezing. My tight chest, feeling of reduced lung capacity and tickly lung sensation had subsided slightly, as did the coughing, that had become painful on Day 2 #Oximeter down to 96%... I slept a lot on Day 3.

But now it's 1am on Day 4 and I feel full of life. Fatigue gone. No more headache. Slight wheeze still, Oximeter 96%; no appetite, but sense of smell and taste are fine.

Wonder whether the worst is over, as I'm double AZ-jabbed plus Pfizer-boosted?
I can't find evidence of people relapsing into worsening symptoms post-Day 3, but my lungs are my weakness... Am I good right now because I slept so much over the last 3 days?

Tomorrow I begin my participation in the @UniofOxford #Molnupiravir (antiviral) trial.

Link follows... ImageImageImage
Read 45 tweets

🚨In Italia 🇮🇹 record di ospedalizzazioni per #COVID19 per la fascia 0-9 anni‼️

👉Eppure vogliono convincerci che #Omicron sia #mild e che tutto vada per il meglio...


🚨In Italia 🇮🇹 record di ospedalizzazioni per #COVID19 per la fascia 10-19 anni‼️


🚨In Italia 🇮🇹 record di ospedalizzazioni per #COVID19 per la fascia 20-29 anni‼️

Read 4 tweets
met de nadruk op "*wanneer* #omikron eenmaal verdwijnt er voor heel wat weken en maanden een periode van wijdverbreide immuniteit zal zijn"

WHO: einde pandemie in Europa mogelijk in zicht via @NOS
de periode ná #omicron zal er prima uit zien
alleen: de weg ernaar toe?
hoeveel ziektelast gaat #omicron geven? #longCOVID?
het verspreidt zich zo snel, dat het inderdaad niet is tegen te houden.
deze tijd lijkt me niet fijn voor mensen met een kwetsbare gezondheid. Voor wie #omicron helemaal niet #mild gaat zijn: door chemokuur of afweeronderdrukkende medicatie.
Read 13 tweets
VE vs omicron
"Among those who had
received 2 doses of AstraZeneca, there was no effect against #Omicron (against symptomatic disease) from 20 weeks after the second dose."

That's among those who have completed their 2nd #COVISHIELD (AZ) dose before Aug 22nd of 2021.
(1/8) Image
#HCWs were vaccinated earliest in India, with majority completing their second dose of AZ as early as April 2021. (That's >35 weeks since 2nd dose)

They currently face greatest exposure risk as noted in many large outbreaks in hospitals and affect delivery of healthcare.
(2/8) Image
At-risk population were vaccinated next in India, and so were the elderly. Vaccine efficacy has shown to have more profound immune waning in elderly individuals.

These populations are an urgent priority, to prevent severe disease & death (The 2x dose still does that well).
Read 10 tweets
Da mesi scrivo su cose per me evidenti ma che sembrano incomprensibili agli altri.
Che il virus fosse airborne era evidente sin dall'inizio, che il virus provochi patologie multisistemiche è ormai palese: ma i concetti vengono ignorati,"rifiutati"
Tutto ciò che si vuol sentire è: "il virus è morto", " è solo un raffreddore", "tanto ora il vaccino mi protegge", " i bambini sono al sicuro" ecc
Ma sono solo confortevoli falsità
Permettiamo che il desiderio alteri la realtà
Può essere politicamente comodo ma non certo sicuro
Mai è stato➡️ chiaramente detto alle persone che il #SARSCoV2 e tutti i suo derivati, #delta, #Omicron e quanti ne verranno sono virus che hanno impatto non solo nell'immediato ma anche a lungo termine
Anche se nei casi asintomatici o paucisintomatici
Come accade per altri virus
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#Impfstoffe, #Booster #Covax & #Kommunikation:

1) #AstraZeneca: #EMA STIKO und #Massenmedien, haben diesen Impfstoff so #kaputt #geredet, dass er ab Juli mehr unter die Leute zu bringen war. Es musste verdammt viel #weggeschmissen worden, statt #kreuzgeimpft (AZ+mRNA)

Obwohl sich abgezeichnet hat, dass eine #Erstimpfung mit #AstraZeneca und eine zeitlich verzögerte #zweite_Impfung mit einem mRNA Impfstoff, einer 2xmRNA Impfung mindestens gleichwertig ist, wurde dieses #heterologe_Impfschema kaum angewendet, da keine STIKO Empfehlung.

Die Schutzwirkung durch das #heterologe_Prime_Boost_Schema mit AZ + mRNA / #Kreuzimpfung, ist höher, und hält deutlich länger an als zweimal AZ
Dennoch hat man zweimal AZ mit kurzem Abstand zwischen beiden Dosen an Die verimpft, die überhaupt noch AZ imfwillig.

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Während der Pandemie haben wir uns an die Vorstellung gewöhnt, dass die meisten #COVID-Fälle „#milde #Verläufe sind.
Zb die #CDC sagt, dass 80 % der symptomatischen #SARSCov2 Infektionen einen "milden Verlauf" haben.
Manche denken: dann #kein Grund zur Sorge. Zurecht?
Im #allgemeinen #Sprachgebrauch beschreibt das Wort #mild idR etwas von #untergeordneter #Bedeutung.
Zum Beispiel wird #Erkältung oft als "#milde #Viruserkrankung" bezeichnet.
#Mild bedeutet also "durchaus evtl  unangenehm aber nicht weiter
von Bedeutung, keine große Sache"
Betrachten wir das Attribut "#mild" im Zusammenhang mit #Covid zeigt sich : #Allgemeiner #Sprachgebrauch und die #medizinische #Definition unterscheiden sich hier #signifikant, werden aber @vermischt, was zu #Verwirrung in der Kommunikation über den wahren Sachverhalt führt.
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Studie belegt #Modelle: Schulen treiben die Pandemie
Diese Studie zeigt, dass in der 2. #Welle der #Lockdown wenig brachte. Erst durch das zusätzliche Schliessen der Geschäfte und #Schulen setzte in Deutschland eine positive Wirkung ein #twlz #RKI #KMK…
Wissenschaftliche Evidence - #Schulen treiben die #Pandemie: Wie haben #RKI/#KMK nach 18 Monaten #Kitas und #Schulen aufgestellt? Keine #Raumluftkonzepte, nicht einmal #Hepaluftfilter, keine geeigneten Hygienepläne, kaum vorbereitet auf Distanzlernen #twlz
zur Krönung: Die #Maskenpflicht wird in den meisten Bundesländern - für die nicht pandemiegerechten #Kitas /#Schulen - aufgehoben. Anstatt #Raumluftkonzepte und #FFP3 beginnt nach den Sommerferien die nächste Runde Infektions-Roulette - diesmal mit #Delta
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Ultimate victims of media induced fear & politically correct #posturing will be our #children. "hygiene hypothesis: "when exposure to parasites, bacteria, & #viruses is limited early in life, children face a greater chance of [] allergies, asthma, & other #autoimmune diseases..." Image
Dec 10, 2020, Nature: "'#Children are very much adapted to respond — & very well equipped to respond — to new #viruses,' [] even when they are infected w/ #SARSCoV2, children are most likely to experience #mild or #asymptomatic illness." Image
"These children’s #immune systems see the #virus & mounts this really quick & effective immune response that shuts it down, before it has a chance to replicate to the point that it comes up positive on the swab diagnostic test",

Natural #Immunity is not a conspiracy theory.
Read 12 tweets
Delighted to be hosting Prof Brad Kurowski ⁦@CincyChildrens⁩ who is presenting his research on #child #braininjury at the ⁦@exeterpsych⁩ Spring Seminar
96.6% of #child #brainunjury are mild - Prof Brad Kurowski
Influences on recovery - individual factors (pre injury ability, genetics, sex, age)
Read 24 tweets

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