Discover and read the best of Twitter Threads about #nervous
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#1 #Covid19 #Supplement thread for #LongCovid #LongHaul #PostCovid. This may help, if you suffer from #fatigue #brainfog #jointpain #inflammation #weakness #depression #anxiety #SOB #clots #fibrosis #myocarditis #heartattack #stroke #alz #memory frontiersin.org/articles/10.33…
#2 B-COMPLEX/MULTI VITAMIN. Buy a liposomal or other form that increases bio-availability. Take 1 capsule w/Breakfast and Lunch. If you have stomach upset, try sublingual (under tongue) EZ Melt B-Complex in AM & Multi w/iron for Dinner. amazon.com/Liposomal-Meth…
#3 OMEGA 3s. Fish Oil, Krill Oil, Algae Oil are all good sources of Omega 3. Be careful the EPA/DHA ratio. EPA helps with inflammation/DHA helps with cognition. You need both! Opt for a 1:1 or 2:1 ratio of DHA to EPA (2:1 ratio eg. 800 DHA/400EPA) amazon.com/3Care-Concentr…
Sometimes I hear people dismiss the possible role of a persistent #pathogen (such as a herpesvirus) in the development of a chronic #disease b/c the same pathogen can be found in healthy people
2/ I see it differently 👉 While the presence/absence of a persistent pathogen in a patient with chronic symptoms matters, the real question is: what is the pathogen doing? Is its ACTIVITY different in patients vs. healthy people?
@jenbrea Hey! So I'm getting to the point where I could write a long paper about potential overlapping connections b/t #Alzheimer's and #MECFS, but I'll summarize a few top trends in this thread! First, I brainstormed often on topic with the late Rob Moir
@jenbrea 2/ Rob’s research (done w/ Rudy Tanzi + Will Eimer at Harvard) forms the core of a potential ongoing paradigm shift in Alzheimer’s - namely that #amyloid beta may be an antimicrobial peptide that forms in response to pathogens in #brain tissue: pubmed.ncbi.nlm.nih.gov/30001512/
@jenbrea 3/ To better understand that research, read this #interview I did with Rob before he passed away last year from glioblastoma. Key to ME/CFS is his work indicates that amyloid may form in response to herpesviruses like HSV1 in the Alzheimer’s brain: microbeminded.com/2017/12/18/int…
@sickanddamned @__ice9 @GemzME @Cov19longtail @VirusesImmunity @MBVanElzakker Walker hi - I very much disagree that #Borrelia or #EBV are typically ” long gone” in infected patients who develop chronic symptoms.
@sickanddamned @__ice9 @GemzME @Cov19longtail @VirusesImmunity @MBVanElzakker 2/ There is a large body of literature showing that even if such #organisms cannot be found in blood, they can persist in certain tissues or the central #nervous system where they are very hard to identify clinically
@sickanddamned @__ice9 @GemzME @Cov19longtail @VirusesImmunity @MBVanElzakker 3/ This is particularly obvious w/ EBV which is a #herpesvirus. Herpesviruses almost never “clear” after #infection, and symptom resolution is due to the immune system’s ability to contain the #virus in a non-replicating state
So, Spritze bekommen. Kleiner Pieks nur, mal sehen, ob er etwas bringt.
Scheint etwas besser geworden zu sein.
Ryan I take issue with your rash conclusion that #COVID-19 cannot survive in a persistent form in certain #LongCovid patients, and it's unfair to say that people studying the topic or discussing the possibility of COVID-19 chronic persistence are spreading rumors or causing harm!
2/ First, there is no way for you to *know* that #COVID-19 cannot persist in a latent/chronic form in certain patients. The #virus has only existed for a short time, meaning few studies on persistence have even been able to be conducted
3/ Second, have you noted all the cell types/body sites #COVID-19 can infect? (below). Have you obtained samples from all such sites in #LongCovid cases + searched for the #virus in a persistent form? (studies of cerebrospinal fluid, tissue biopsy etc?) nature.com/articles/s4159…
Cool paper detailing what body sites, cell types, symptoms #COVID-19 has been connected to thus far 👉 But one thing: everyone knows that most persistent #viral (and #bacterial) pathogens are capable of #infecting/driving an equally extensive # of #symptoms, right?
2/ For example, in this interview, Dharam Ablashi (who co-discovered the #virus HHV6) explains how HHV6 has been shown capable of contributing to #cancers, type 1 #diabetes, Hashimoto’s, #MS, HPA-axis dysregulation, ME/CFS, Alzheimer’s, neuroinflammation..microbeminded.com/2020/06/28/int…
3/ ..and that the HHV6 can survive in
#microglia, astrocytes, macrophage, neurons/nerves, #pancreatic islet cells, the lung, gut epithelial cells, the #liver etc etc etc!
#microglia, astrocytes, macrophage, neurons/nerves, #pancreatic islet cells, the lung, gut epithelial cells, the #liver etc etc etc!
I study the illness #ME/CFS - a neuroinflammatory condition that usually begins w/ a #viral infection (sometimes a #respiratory infection!). I have argued for years that infecting #pathogens tied to the illness might persist in the central nervous system (CNS) of such patients
2/ While I realize this article is talking about acute #infection and #COVID19 - it explains that #SARS-CoV-2 “might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths:”
the-scientist.com/news-opinion/l…
the-scientist.com/news-opinion/l…
3/ Matt Anderson, (one of my favorite Beth Israel pathologists!) states, “Some of the purely respiratory symptoms that you might attribute to the #disease, the inability to get air into the #lungs, might actually be defects in #respiration controlled by the #nervous system.” 
Incredible new study 👉 Demonstrates that #gut-innervating nociceptor #neurons modulate several layers of GI physiology including regulation of #Payers Patch M cells + small intestine microbial communities + defense against enteric pathogen Salmonella: sciencedirect.com/science/articl…
2/ Overall the study expands the role of the #nervous system in host defense and suggests that “manipulation of #neurons and their mediators could be a target for therapies to treat inflammatory and #infectious diseases”
3/ For more info on the study check out this press release which describes the findings in more simple terms: news.harvard.edu/gazette/story/…
The gene ApoE impacts mobilization + redistribution of #lipids and cholesterol during neuronal growth and repair 👉 Using a murine model of acute hematogenous HSV-1 #infection, this team found that viral neuroinvasion was reduced in mice lacking ApoE compared to wild-type mice
2/2 In the mice, ApoE dose was directly linked to the Herpes Simplex-1 DNA concentration detected in the #nervous system. ApoE4 was also more efficient than ApoE3 in promoting colonization of the brain by HSV-1.
3/3 Team says: “If an interaction between ApoE and HSV-1 has anything to do with #Alzheimer’s this may occur during latency” and “The relationship between these two risk factors for ALzheimer’s could be of great importance in the pathogenesis of this disease.”
#WSV2019 #Welcome_reception
Panel #discussion of the #prospective #plans of @WSVirology
#USA @uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc
Panel #discussion of the #prospective #plans of @WSVirology
#USA @uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc
@uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc #WSV2019 | #Janusz_Paweska | Wonderful Presentation of #South_African #mobile_laboratory_response to #Ebola outbreak in #West_Africa in the first meeting of WSV @WSVirology, #Stockholm 2019
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc @edrybicki
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc @edrybicki
@uppsalauni @karolinskainst @ESCMID @ESCVirology @swedishvirology @SLU_Virology @RedMexVirologia @sareengalbraith @rosamdelangel @foodsafetynews @VirolColombia @AusVirologySoc @edrybicki #WSV2019 | Prof. #Ziad_Memish | #MERS_CoV an emerging #virus from the #ArabianPeninsula in the first meeting of WSV@WSVirology, #Stockholm 2019
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc #coronavirus #SaudiNationalDay #SaudiArabia @Alfaisaluniv
ws-virology.org
@VirolColombia @RedMexVirologia @AusVirologySoc #coronavirus #SaudiNationalDay #SaudiArabia @Alfaisaluniv
